Home Carboxes 117414-74-1
117414-74-1,MFCD00878116
Catalog No.:AA000E70

117414-74-1 | 2-Piperazinecarboxylic acid, 4-[(2E)-3-phosphono-2-propenyl]-, (2R)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥98%
in stock  
$761.00   $533.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000E70
Chemical Name:
2-Piperazinecarboxylic acid, 4-[(2E)-3-phosphono-2-propenyl]-, (2R)-
CAS Number:
117414-74-1
Molecular Formula:
C8H15N2O5P
Molecular Weight:
250.1889
MDL Number:
MFCD00878116
SMILES:
OC(=O)[C@@H]1NCCN(C1)C/C=C/P(=O)(O)O
Properties
Computed Properties
 
Complexity:
326  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
4  
XLogP3:
-7  

Literature

Title: CCK-induced reduction of food intake and hindbrain MAPK signaling are mediated by NMDA receptor activation.

Journal: Endocrinology 20120601

Title: Reduction of food intake by cholecystokinin requires activation of hindbrain NMDA-type glutamate receptors.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20110801

Title: An examination of NMDA receptor contribution to conditioned responding evoked by the conditional stimulus effects of nicotine.

Journal: Psychopharmacology 20110101

Title: NMDA NR2 receptors participate in CCK-induced reduction of food intake and hindbrain neuronal activation.

Journal: Brain research 20090417

Title: Blockade of hindbrain NMDA receptors containing NR2 subunits increases sucrose intake.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20090401

Title: Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit.

Journal: American journal of physiology. Endocrinology and metabolism 20080701

Title: Importance of screening logs in clinical trials for severe traumatic brain injury.

Journal: Neurosurgery 20080601

Title: Lowered brain stimulation reward thresholds in rats treated with a combination of caffeine and N-methyl-D-aspartate but not alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate or metabotropic glutamate receptor-5 receptor antagonists.

Journal: Behavioural pharmacology 20060601

Title: Effects of modulators of N-methyl-D-aspartate receptor-mediated neurotransmission on diazepam discrimination in rats.

Journal: Life sciences 20040528

Title: Synthesis and anticonvulsant activity of novel bicyclic acidic amino acids.

Journal: Journal of medicinal chemistry 20030703

Title: Inactivation of amino acid receptors in medullary reticular formation modulates and suppresses ingestion and rejection responses in the awake rat.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030701

Title: Involvement of glutamate receptors within the central nucleus of the amygdala in naloxone-precipitated morphine withdrawal-induced conditioned place aversion in rats.

Journal: Japanese journal of pharmacology 20020401

Title: The competitive NMDA receptor antagonist CPPene stimulates NREM sleep and eating in rats.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020301

Title: Effects of the NMDA receptor antagonist, D-CPPene, on sensitization to the operant decrement produced by naloxone in morphine-treated rats.

Journal: Behavioural pharmacology 20010401

Title: NMDA receptor antagonists do not block the development of sensitization of catalepsy, but make its expression state-dependent.

Journal: Behavioural pharmacology 20010401

Title: Thermal sterilization of heat-sensitive products using high-temperature short-time sterilization.

Journal: Journal of pharmaceutical sciences 20010301

Title: Evaluation of HIV-1 Tat induced neurotoxicity in rat cortical cell culture.

Journal: Journal of neurovirology 20010201

Title: N6-cyclohexyladenosine and 3-(2-carboxypiperazine-4-yl)-1-propenyl-1-phosphonic acid enhance the effect of antiepileptic drugs against induced seizures in mice.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20010101

Title: Effects of some excitatory amino acid antagonists on imipenem-induced seizures in DBA/2 mice.

Journal: Brain research 19950206

Title: [Effects of antagonists of NMDA receptor on methamphetamine-induced decrease in the dopamine uptake sites in the rat striatum and on the behavioral sensitization].

Journal: [Hokkaido igaku zasshi] The Hokkaido journal of medical science 19930501

Title: Competitive and noncompetitive N-methyl-D-aspartate antagonists protect dopaminergic and serotonergic neurotoxicity produced by methamphetamine in various brain regions.

Journal: Journal of neural transmission. General section 19930101

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 117414-74-1
Tags:117414-74-1 Molecular Formula|117414-74-1 MDL|117414-74-1 SMILES|117414-74-1 2-Piperazinecarboxylic acid, 4-[(2E)-3-phosphono-2-propenyl]-, (2R)-