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1185-57-5,MFCD00013099
Catalog No.:AA003NSA

1185-57-5 | Ammonium ferric citrate

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25g
20-22.5%Fe
in stock  
$24.00   $17.00
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100g
20-22.5%Fe
in stock  
$45.00   $32.00
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500g
20-22.5%Fe
in stock  
$107.00   $75.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003NSA
Chemical Name:
Ammonium ferric citrate
CAS Number:
1185-57-5
Molecular Formula:
C12H22FeN3O14
Molecular Weight:
488.1598
MDL Number:
MFCD00013099
SMILES:
[O-]C(=O)C(CC(=O)[O-])(CC(=O)[O-])O.[O-]C(=O)C(CC(=O)[O-])(CC(=O)[O-])O.[Fe+3].[NH4+].[NH4+].[NH4+]
UN Number:
3077
Properties
Properties
 
Form:
Solid  
MP:
>193°C (dec.)  
Solubility:
1200g/l  
Stability:
Hygroscopic  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
233  
Covalently-Bonded Unit Count:
3  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
5  

Literature

Title: Iron overload-induced calcium signals modulate mitochondrial fragmentation in HT-22 hippocampal neuron cells.

Journal: Toxicology 20160715

Title: Ferric ion could facilitate osteoclast differentiation and bone resorption through the production of reactive oxygen species.

Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20121101

Title: Iron excess limits HHIPL-2 gene expression and decreases osteoblastic activity in human MG-63 cells.

Journal: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20121001

Title: Iron and holotransferrin induce cAMP-dependent differentiation of Schwann cells.

Journal: Neurochemistry international 20121001

Title: α-Synuclein expression is modulated at the translational level by iron.

Journal: Neuroreport 20120620

Title: Iron overload inhibits calcification and differentiation of ATDC5 cells.

Journal: Journal of biochemistry 20120101

Title: Efficiency of ferritin as an MRI reporter gene in NPC cells is enhanced by iron supplementation.

Journal: Journal of biomedicine & biotechnology 20120101

Title: Ferritin heavy chain-mediated iron homoeostasis regulates expression of IL-10 in Chlamydia trachomatis-infected HeLa cells.

Journal: Cell biology international 20110801

Title: Increased cellular iron levels affect matrix metalloproteinase expression and phagocytosis in activated microglia.

Journal: Neuroscience letters 20110801

Title: HFE polymorphisms affect cellular glutamate regulation.

Journal: Neurobiology of aging 20110601

Title: Expression and iron-dependent regulation of succinate receptor GPR91 in retinal pigment epithelium.

Journal: Investigative ophthalmology & visual science 20110501

Title: Serum hepcidin and macrophage iron correlate with MCP-1 release and vascular damage in patients with metabolic syndrome alterations.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20110301

Title: Redox control of iron regulatory protein 2 stability.

Journal: FEBS letters 20110218

Title: Iron overload triggers redox-sensitive signals in human IMR-32 neuroblastoma cells.

Journal: Neurotoxicology 20110101

Title: Lysosomal proteolysis is the primary degradation pathway for cytosolic ferritin and cytosolic ferritin degradation is necessary for iron exit.

Journal: Antioxidants & redox signaling 20101001

Title: Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter.

Journal: Haematologica 20100801

Title: Effects of iron chelators, iron salts, and iron oxide nanoparticles on the proliferation and the iron content of oligodendroglial OLN-93 cells.

Journal: Neurochemical research 20100801

Title: Prospective comparative study of negative oral contrast agents for magnetic resonance cholangiopancreatography.

Journal: Japanese journal of radiology 20100201

Title: Paradoxical role of prion protein aggregates in redox-iron induced toxicity.

Journal: PloS one 20100101

Title: Defining juxtapapillary diverticulum with 3D segmented trueFISP MRCP: comparison with conventional MRCP sequences with an oral negative contrast agent.

Journal: Japanese journal of radiology 20091201

Title: Curcumin reduces the toxic effects of iron loading in rat liver epithelial cells.

Journal: Liver international : official journal of the International Association for the Study of the Liver 20090101

Title: Influence of HFE variants and cellular iron on monocyte chemoattractant protein-1.

Journal: Journal of neuroinflammation 20090101

Title: Gentian violet and ferric ammonium citrate disrupt Pseudomonas aeruginosa biofilms.

Journal: The Laryngoscope 20081101

Title: Iron increases MMP-9 expression through activation of AP-1 via ERK/Akt pathway in human head and neck squamous carcinoma cells.

Journal: Oral oncology 20080601

Title: [Elimination of bowel fluid artifact on abdominal DWI using oral contrast agent ferric ammonium citrate].

Journal: Nihon Hoshasen Gijutsu Gakkai zasshi 20080520

Title: Iron-chelator complexes as iron sources for early developing human erythroid precursors.

Journal: Translational research : the journal of laboratory and clinical medicine 20080201

Title: Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron.

Journal: BMC gastroenterology 20080101

Title: Divalent metal transporter 1 up-regulation is involved in the 6-hydroxydopamine-induced ferrous iron influx.

Journal: Journal of neuroscience research 20071101

Title: [Oral ferric ammonium citrate solution in MRCP for diagnosing low-level obstructive jaundice].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20070401

Title: Apoptosis induced by crocidolite asbestos in human lung epithelial cells involves inactivation of Akt and MAPK pathways.

Journal: Apoptosis : an international journal on programmed cell death 20070201

Title: Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity.

Journal: Journal of neuroscience research 20060815

Title: Iron regulatory protein-independent regulation of ferritin synthesis by nitrogen monoxide.

Journal: The FEBS journal 20060801

Title: The influence of gallium and other metal ions on the uptake of non-transferrin-bound iron by rat hepatocytes.

Journal: Biochimie 20060601

Title: Enhanced contrast of bacteriophage plaques in Salmonella with ferric ammonium citrate and sodium thiosulfate (FACST) and tetrazolium red (TZR).

Journal: Journal of microbiological methods 20060501

Title: Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A.

Journal: Toxicology 20060116

Title: Iron loading inhibits ferroportin1 expression in PC12 cells.

Journal: Neurochemistry international 20051201

Title: Divalent metal transporter-1 decreases metal-related injury in the lung.

Journal: American journal of physiology. Lung cellular and molecular physiology 20050901

Title: Increased iron-induced oxidative stress and toxicity in scrapie-infected neuroblastoma cells.

Journal: Neuroscience letters 20050715

Title: Iron salts perturb biofilm formation and disrupt existing biofilms of Pseudomonas aeruginosa.

Journal: Chemistry & biology 20050701

Title: Effects of extracellular iron concentration on calcium absorption and relationship between Ca2+ and cell apoptosis in Caco-2 cells.

Journal: World journal of gastroenterology 20050521

Title: Iron absorption by human subjects from different iron fortification compounds added to Thai fish sauce.

Journal: European journal of clinical nutrition 20050501

Title: Changed iron regulation in scrapie-infected neuroblastoma cells.

Journal: Brain research. Molecular brain research 20050218

Title: The potential of encapsulated iron compounds in food fortification: a review.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20041101

Title: Modulation of iron on mitochondrial aconitase expression in human prostatic carcinoma cells.

Journal: Molecular and cellular biochemistry 20041001

Title: Pharmacological but not physiological concentrations of melatonin reduce iron-induced neuronal death in rat cerebral cortex.

Journal: Neuroscience letters 20040527

Title: Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin.

Journal: Blood 20040315

Title: Iron accumulation, iron-mediated toxicity and altered levels of ferritin and transferrin receptor in cultured astrocytes during incubation with ferric ammonium citrate.

Journal: Journal of neurochemistry 20040301

Title: Expression of the SLC11A1 (NRAMP1) 5'-(GT)n repeat: opposite effect in the presence of -237C-->T.

Journal: Blood cells, molecules & diseases 20040101

Title: Human Abeta1-42 reduces iron-induced toxicity in rat cerebral cortex.

Journal: Journal of neuroscience research 20030801

Title: [Effect of iron on vasoconstriction in the isolated rat aorta].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20030625

Title: [Modulation of iron on the vasodilating effect of interleukin-2 in the isolated aortic ring].

Journal: Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20030601

Title: Relationships and distinctions in iron-regulatory networks responding to interrelated signals.

Journal: Blood 20030501

Title: Iron uptake and Nramp2/DMT1/DCT1 in human bronchial epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology 20020501

Title: Acquisition, storage and release of iron by cultured human hepatoma cells.

Journal: Journal of hepatology 20020101

Title: Numerous proteins in Mammalian cells are prone to iron-dependent oxidation and proteasomal degradation.

Journal: Developmental neuroscience 20020101

Title: Influence of interactions between temperature, ferric ammonium citrate and glycine betaine on the growth of Listeria monocytogenes in a defined medium.

Journal: Letters in applied microbiology 20020101

Title: Iron prevents ferritin turnover in hepatic cells.

Journal: The Journal of biological chemistry 20011228

Title: Absorption of unlabeled reduced iron of small particle size from a commercial source. A method to predict absorption of unlabeled iron compounds in humans.

Journal: Archivos latinoamericanos de nutricion 20010901

Title: Quantitative analysis of cell death and ferritin expression in response to cortical iron: implications for hypoxia-ischemia and stroke.

Journal: Brain research 20010713

Title: Increased release of arachidonic acid and eicosanoids in iron-overloaded cardiomyocytes.

Journal: Circulation 20010515

Title: Iron and gallium increase iron uptake from transferrin by human melanoma cells: further examination of the ferric ammonium citrate-activated iron uptake process.

Journal: Biochimica et biophysica acta 20010430

Title: Interferon-gamma and lipopolysaccharide regulate the expression of Nramp2 and increase the uptake of iron from low relative molecular mass complexes by macrophages.

Journal: European journal of biochemistry 20001101

Title: Shenglin Fang, et al. Effects of intracellular iron overload on cell death and identification of potent cell death inhibitors. Biochem Biophys Res Commun. 2018 Sep 3;503(1):297-303.

Title: Yu-Cheng Lai, et al. Towards protein production and application by using Chlorella species as circular economy. Bioresour Technol. 2019 Oct;289:121625.

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