Home Other Building Blocks 1187990-87-9
1187990-87-9,MFCD22572348
Catalog No.:AA0096QA

1187990-87-9 | Mk-8617

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$12.00   $8.00
- +
5mg
97%
in stock  
$27.00   $19.00
- +
10mg
97%
in stock  
$41.00   $29.00
- +
  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA0096QA
Chemical Name:
Mk-8617
CAS Number:
1187990-87-9
Molecular Formula:
C24H21N5O4
Molecular Weight:
443.4546
MDL Number:
MFCD22572348
SMILES:
COc1ccc(cc1)C(c1ccc(cc1)OC)NC(=O)c1cnc(nc1O)c1cccnn1
Properties
Computed Properties
 
Complexity:
730  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
7  
XLogP3:
2.4  

Literature

Title: Debenham JS, et al. Discovery of N-[Bis(4-methoxyphenyl)methyl-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide (MK-8617), an Orally Active Pan-Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase 1-3 (HIF PHD1-3) for the Treatment of Anemia. J Med Chem. 2016 Dec 22;59(24):11039-11049.

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SDS
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Tags:1187990-87-9 Molecular Formula|1187990-87-9 MDL|1187990-87-9 SMILES|1187990-87-9 Mk-8617