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119169-78-7,MFCD00864172
Catalog No.:AA000I6X

119169-78-7 | Epristeride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
99%
1 week  
$527.00   $369.00
- +
10mg
99
1 week  
$577.00   $404.00
- +
50mg
99
1 week  
$1,649.00   $1,154.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000I6X
Chemical Name:
Epristeride
CAS Number:
119169-78-7
Molecular Formula:
C25H37NO3
Molecular Weight:
399.5662
MDL Number:
MFCD00864172
SMILES:
OC(=O)C1=CC2=CC[C@@H]3[C@@H]([C@]2(CC1)C)CC[C@]1([C@H]3CC[C@@H]1C(=O)NC(C)(C)C)C
Properties
Computed Properties
 
Complexity:
788  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
5.1  

Literature

Title: Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor.

Journal: Bioorganic & medicinal chemistry letters 20110101

Title: Self organizing molecular field analysis on a series of human 5alpha-reductase inhibitors: unsaturated 3-carboxysteroid.

Journal: European journal of medicinal chemistry 20091201

Title: [Comparison of different drugs on the treatment of benign prostate hyperplasia].

Journal: Zhonghua wai ke za zhi [Chinese journal of surgery] 20070715

Title: [Effect of large-dosage of 5alpha-reductase inhibitors on the spermatogenesis of male rats].

Journal: Zhonghua nan ke xue = National journal of andrology 20050901

Title: Twelve-year follow up of a randomized prospective trial comparing bacillus Calmette-Guerin and epirubicin as adjuvant therapy in superficial bladder cancer.

Journal: International journal of urology : official journal of the Japanese Urological Association 20050501

Title: Comparative study of human steroid 5alpha-reductase isoforms in prostate and female breast skin tissues: sensitivity to inhibition by finasteride and epristeride.

Journal: Life sciences 20020531

Title: Effect of epristeride on the expression of IGF-1 and TGF-beta receptors in androgen-induced castrated rat prostate.

Journal: Experimental biology and medicine (Maywood, N.J.) 20011101

Title: Inhibition of regrowth of prostatic glandular cells by epristeride.

Journal: Acta pharmacologica Sinica 20010901

Title: Qian LH, et al. Inhibition of regrowth of prostatic glandular cells by epristeride. Acta Pharmacol Sin. 2001 Sep;22(9):847-50.

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