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1191995-00-2,MFCD22376579
Catalog No.:AA01V2RN

1191995-00-2 | Dorzagliatin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
97%
in stock  
$51.00   $36.00
- +
10mg
97%
in stock  
$75.00   $53.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01V2RN
Chemical Name:
Dorzagliatin
CAS Number:
1191995-00-2
Molecular Formula:
C22H27ClN4O5
Molecular Weight:
462.9266
MDL Number:
MFCD22376579
SMILES:
OC[C@@H](Cn1ccc(n1)NC(=O)[C@@H](N1CC(=CC1=O)Oc1ccccc1Cl)CC(C)C)O
Properties

Downstream Synthesis Route

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-US2009/264445,2009,A1Locationinpatent:Page/Pagecolumn60

Literature

Title: Zhu XX, et al. Dorzagliatin (HMS5552), a novel dual-acting glucokinase activator, improves glycaemic control and pancreatic β-cell function in patients with type 2 diabetes: A 28-day treatment study using biomarker-guided patient selection. Diabetes Obes Metab. 2018 Sep;20(9):2113-2120.

Title: Wang P, et al. Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus. J Diabetes Res. 2017;2017:5812607.

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