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1200133-34-1,MFCD25541650
Catalog No.:AA008THQ

1200133-34-1 | Vch-916

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
1 week  
$163.00   $114.00
- +
5mg
98%
1 week  
$289.00   $202.00
- +
10mg
98%
1 week  
$368.00   $258.00
- +
50mg
98%
1 week  
$1,003.00   $702.00
- +
100mg
98%
1 week  
$1,797.00   $1,258.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008THQ
Chemical Name:
Vch-916
CAS Number:
1200133-34-1
Molecular Formula:
C26H36KNO4S
Molecular Weight:
497.7316
MDL Number:
MFCD25541650
SMILES:
COC1CCC(CC1)N(c1cc(sc1C(=O)[O-])C1=CCCCC1)C(=O)C1CCC(CC1)C.[K+]
Properties
Computed Properties
 
Complexity:
700  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
6  

Literature

Title: Ludmila Gerber, Tania M. Welzel, Stefan Zeuzem. New therapeutic strategies in HCV: polymerase inhibitors. Liver International. 2013,33(s1): 85-92

Title: Abdelrahman S. Mayhoub. Hepatitis C RNA-dependent RNA polymerase inhibitors: A review of structure-activity and resistance relationships; different scaffolds and mutations. Bioorganic & Medicinal Chemistry. 2012, 20 (10): 3150-3161.

Title: Debasis Dasa, Jian Honga, Shu-Hui Chena, et al. Recent advances in drug discovery of benzothiadiazine and related analogs as HCV NS5B polymerase inhibitors. Bioorganic & Medicinal Chemistry. 2011, 19(16): 4690-4703

Title: Pierre L Beaulieu. Recent advances in the development of NS5B polymerase inhibitors for the treatment of hepatitis C virus infection. Informahealthcare. 2009, 19(2): 145-164

Title: Safety,Tolerability and Pharmacokinetics of Multiple Ascending Doses of VCH 916 in Subjects With Chronic Hep C Infection

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SDS
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Tags:1200133-34-1 Molecular Formula|1200133-34-1 MDL|1200133-34-1 SMILES|1200133-34-1 Vch-916