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120068-36-2,MFCD01938707
Catalog No.:AA008RI9

120068-36-2 | FIPRONIL-SULFONE

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Purity
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20mg
2 weeks  
$555.00   $389.00
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50mg
2 weeks  
$845.00   $592.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008RI9
Chemical Name:
FIPRONIL-SULFONE
CAS Number:
120068-36-2
Molecular Formula:
C12H4Cl2F6N4O2S
Molecular Weight:
453.1472
MDL Number:
MFCD01938707
SMILES:
N#Cc1nn(c(c1S(=O)(=O)C(F)(F)F)N)c1c(Cl)cc(cc1Cl)C(F)(F)F
Properties
Computed Properties
 
Complexity:
706  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
4.7  

Literature

Title: The nuclear receptors pregnane X receptor and constitutive androstane receptor contribute to the impact of fipronil on hepatic gene expression linked to thyroid hormone metabolism.

Journal: Biochemical pharmacology 20131001

Title: CYP450-dependent biotransformation of the insecticide fipronil into fipronil sulfone can mediate fipronil-induced thyroid disruption in rats.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20120501

Title: Thyroid function tests in persons with occupational exposure to fipronil.

Journal: Thyroid : official journal of the American Thyroid Association 20110701

Title: Chemical residence time and hydrological conditions influence treatment of fipronil in vegetated aquatic mesocosms.

Journal: Journal of environmental quality 20110101

Title: Quantification of fipronil and its metabolite fipronil sulfone in rat plasma over a wide range of concentrations by LC/UV/MS.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100715

Title: Is the mechanisms of fipronil-induced thyroid disruption specific of the rat: Re-evaluation of fipronil thyroid toxicity in sheep?

Journal: Toxicology letters 20100504

Title: The insecticide fipronil and its metabolite fipronil sulphone inhibit the rat alpha1beta2gamma2L GABA(A) receptor.

Journal: British journal of pharmacology 20081101

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