Home Other Building Blocks 1204317-86-1
1204317-86-1,MFCD30533433
Catalog No.:AA01EO7D

1204317-86-1 | Edasalonexent

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
1 week  
$527.00   $369.00
- +
10mg
98%
1 week  
$812.00   $569.00
- +
25mg
98%
1 week  
$1,416.00   $991.00
- +
50mg
98%
1 week  
$2,209.00   $1,547.00
- +
100mg
98%
1 week  
$2,987.00   $2,091.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EO7D
Chemical Name:
Edasalonexent
CAS Number:
1204317-86-1
Molecular Formula:
C31H42N2O3
Molecular Weight:
490.6768
MDL Number:
MFCD30533433
SMILES:
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)NCCNC(=O)c1ccccc1O
Properties
Computed Properties
 
Complexity:
762  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
6  
Heavy Atom Count:
36  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
18  
XLogP3:
7.1  

Literature

Title: Hammers DW, et al. Disease-modifying effects of orally bioavailable NF-κB inhibitors in dystrophin-deficient muscle. JCI Insight. 2016 Dec 22;1(21):e90341.

Title: Donovan JM, et al. A Novel NF-κB Inhibitor, Edasalonexent (CAT-1004), in Development as a Disease-Modifying Treatment for Patients With Duchenne Muscular Dystrophy: Phase 1 Safety, Pharmacokinetics, and Pharmacodynamics in Adult Subjects. J Clin Pharmacol. 2017 May;57(5):627-639.

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SDS
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