Title: Discovery of N6-phenyl-1H-pyrazolo[3,4-d]pyrimidine-3,6-diamine derivatives as novel CK1 inhibitors using common-feature pharmacophore model based virtual screening and hit-to-lead optimization.
Journal: European journal of medicinal chemistry 20121001
Title: Sonic Hedgehog dependent phosphorylation by CK1α and GRK2 is required for ciliary accumulation and activation of smoothened.
Journal: PLoS biology 20110601
Title: ATP-binding site of bacterial enzymes as a target for antibacterial drug design.
Journal: Journal of medicinal chemistry 20110224
Title: Crystal structures of two aminoglycoside kinases bound with a eukaryotic protein kinase inhibitor.
Journal: PloS one 20110101
Title: Neurite outgrowth of mature retinal ganglion cells and PC12 cells requires activity of CK1δ and CK1ε.
Journal: PloS one 20110101
Title: 3,4-Diaryl-isoxazoles and -imidazoles as potent dual inhibitors of p38alpha mitogen activated protein kinase and casein kinase 1delta.
Journal: Journal of medicinal chemistry 20091210
Title: In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction.
Journal: Journal of cell science 20090901
Title: Interfering with Wnt signalling alters the periodicity of the segmentation clock.
Journal: Developmental biology 20090601
Title: Upregulation of casein kinase 1epsilon in dorsal root ganglia and spinal cord after mouse spinal nerve injury contributes to neuropathic pain.
Journal: Molecular pain 20090101
Title: Circadian and pharmacological regulation of casein kinase I in the hamster suprachiasmatic nucleus.
Journal: Journal of genetics 20081201
Title: Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening.
Journal: Bioorganic & medicinal chemistry letters 20081015
Title: The selectivity of protein kinase inhibitors: a further update.
Journal: The Biochemical journal 20071215
Title: Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities.
Journal: Molecular cell 20050805
Title: Casein kinase I attenuates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by regulating the recruitment of fas-associated death domain and procaspase-8 to the death-inducing signaling complex.
Journal: Cancer research 20041101
Title: Crystallization and preliminary crystallographic analysis of 3'-aminoglycoside kinase type IIIa complexed with a eukaryotic protein kinase inhibitor, CKI-7.
Journal: Acta crystallographica. Section D, Biological crystallography 20041001
Title: Interactions between FGF and Wnt signals and Tbx3 gene expression in mammary gland initiation in mouse embryos.
Journal: Journal of anatomy 20040701
Title: Phosphorylation of clock protein PER1 regulates its circadian degradation in normal human fibroblasts.
Journal: The Biochemical journal 20040515
Title: Protein kinase CK1 from Trypanosoma cruzi.
Journal: Journal of protein chemistry 20030801
Title: Casein kinase 1 regulates connexin-43 gap junction assembly.
Journal: The Journal of biological chemistry 20021122
Title: Biochemical and enzymatic characterization of a partially purified casein kinase-1 like activity from Trypanosoma cruzi.
Journal: Parasitology international 20020301
Title: Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency.
Journal: Antiviral chemistry & chemotherapy 19990901
