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121264-04-8,MFCD00153814
Catalog No.:AA007QFO

121264-04-8 | ICI-204,448 hydrochloride

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Purity
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5mg
≥98%(HPLC)
in stock  
$243.00   $170.00
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10mg
≥98%(HPLC)
in stock  
$454.00   $318.00
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25mg
≥98%(HPLC)
in stock  
$695.00   $487.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007QFO
Chemical Name:
ICI-204,448 hydrochloride
CAS Number:
121264-04-8
Molecular Formula:
C23H27Cl3N2O4
Molecular Weight:
501.8305
MDL Number:
MFCD00153814
SMILES:
OC(=O)COc1cccc(c1)C(N(C(=O)Cc1ccc(c(c1)Cl)Cl)C)CN1CCCC1.Cl
Properties
Computed Properties
 
Complexity:
602  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
9  
Undefined Atom Stereocenter Count:
1  

Literature

Title: Effects of peripheral μ, δ, and Κ-opioid receptor agonists on the levels of anxiety and motor activity of rats.

Journal: Bulletin of experimental biology and medicine 20120901

Title: Effects of peripherally restricted κ opioid receptor agonists on pain-related stimulation and depression of behavior in rats.

Journal: The Journal of pharmacology and experimental therapeutics 20120301

Title: Subcutaneous, intrathecal and periaqueductal grey administration of asimadoline and ICI-204448 reduces tactile allodynia in the rat.

Journal: European journal of pharmacology 20071114

Title: Assay principle for modulators of protein-protein interactions and its application to non-ATP-competitive ligands targeting protein kinase A.

Journal: Analytical chemistry 20061215

Title: Mu and kappa opioid receptor agonists antagonize icilin-induced wet-dog shaking in rats.

Journal: European journal of pharmacology 20061010

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Effect of exogenous kappa-opioid receptor activation in rat model of myocardial infarction.

Journal: Journal of cardiovascular pharmacology 20040301

Title: Kappa opioid agonist-induced changes in IOP: correlation with 3H-NE release and cAMP accumulation.

Journal: Experimental eye research 20010801

Title: Elevation of atrial natriuretic peptide levels in aqueous humor of the rabbit by kappa opioid receptor agonists.

Journal: Neuropeptides 20010101

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Tags:121264-04-8 Molecular Formula|121264-04-8 MDL|121264-04-8 SMILES|121264-04-8 ICI-204,448 hydrochloride