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121505-94-0,MFCD09997727
Catalog No.:AA00150T

121505-94-0 | N-Alpha-cbz-glycine n-methoxy-n-methylamide

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Price(USD)
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100mg
95%
in stock  
$159.00   $111.00
- +
250mg
95%
in stock  
$254.00   $178.00
- +
1g
95%
in stock  
$312.00   $219.00
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2g
95%
in stock  
$595.00   $417.00
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5g
95%
in stock  
$836.00   $585.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00150T
Chemical Name:
N-Alpha-cbz-glycine n-methoxy-n-methylamide
CAS Number:
121505-94-0
Molecular Formula:
C12H16N2O4
Molecular Weight:
252.2664
MDL Number:
MFCD09997727
SMILES:
COCNC(=O)CNC(=O)OCc1ccccc1
Properties
Computed Properties
 
Complexity:
277  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
1  

Downstream Synthesis Route

[1]Hioki,Kazuhito;Kobayashi,Hiroko;Ohkihara,Rumi;Tani,Shohei;Kunishima,Munetaka[ChemicalandPharmaceuticalBulletin,2004,vol.52,#4,p.470-472]

[2]Braun,Manfred;Waldmueller,Delia[Synthesis,1989,#11,p.856-858]

[3]Hooper,JoelF.;Seo,Sangwon;Truscott,FionaR.;Neuhaus,JamesD.;Willis,MichaelC.[JournaloftheAmericanChemicalSociety,2016,vol.138,#5,p.1630-1634]

[4]CurrentPatentAssignee:SHIONOGI&CO.,LTD.-EP1422218,2004,A1Locationinpatent:Page94

[5]Farese,Audrey;Patino,Nadia;Condom,Roger;Dalleu,Sandrine;Guedj,Roger[TetrahedronLetters,1996,vol.37,#9,p.1413-1416]

[6]Ooi,Takashi;Takeuchi,Mifune;Kato,Daisuke;Uematsu,Yukitaka;Tayama,Eiji;Sakai,Daiki;Maruoka,Keiji[JournaloftheAmericanChemicalSociety,2005,vol.127,#14,p.5073-5083]

[7]Claudel,Stéphanie;Olszewski,TomaszKrzysztof;Mutzenardt,Pierre;Aroulanda,Christie;Coutrot,Philippe;Grison,Claude[Tetrahedron,2006,vol.62,#8,p.1787-1798]

[8]Cai,Zhengjun;Chen,Bingyi;Cheng,Bao;Gu,Qiong;Guo,Junsong;Luo,Zhiteng;Xu,Jun;Yu,Ying;Zhou,Huihao[JournalofMedicinalChemistry,2022,vol.65,#7,p.5800-5820]

[9]Newton,GaryK.;Perrior,TrevorR.;Jenkins,Kerry;Major,MerielR.;Key,RebekahE.;Stewart,MarkR.;Firth-Clark,Stuart;Lloyd,StevenM.;Zhang,Jihui;Francis-Newton,NicolaJ.;Richardson,JonathanP.;Chen,Jie;Lai,Pei;Garrod,DavidR.;Robinson,Clive[JournalofMedicinalChemistry,2014,vol.57,#22,p.9447-9462]

[10]Tashiro,Shohei;Matsuoka,Koji;Minoda,Ai;Shionoya,Mitsuhiko[AngewandteChemie-InternationalEdition,2012,vol.51,#52,p.13123-13127][Angew.Chem.,2012,vol.124,#52,p.13300-13304,5]

[11]Sibi;Stessman;Schultz;Christensen;Lu;Marvin[SyntheticCommunications,1995,vol.25,#8,p.1255-1264]

[12]Kanai,Hayato;Yamada,Kuniyo;Kodama,Koichi;Ishida,Yasuhiro[Chirality,2022,vol.34,#2,p.295-305]

[13]CurrentPatentAssignee:BAYERAG;BROADINSTITUTE-WO2021/94434,2021,A1Locationinpatent:Page/Pagecolumn108-109

[14]CurrentPatentAssignee:MARPTHERAPEUTICS-US2009/221557,2009,A1Locationinpatent:Page/Pagecolumn119

[15]CurrentPatentAssignee:MIMETICA-WO2010/96853,2010,A1Locationinpatent:Page/Pagecolumn72-73

[16]CurrentPatentAssignee:MIMETICA-WO2010/96854,2010,A1Locationinpatent:Page/Pagecolumn88

[17]CurrentPatentAssignee:MIMETICA-US2012/141392,2012,A1Locationinpatent:Page/Pagecolumn41

[18]Vernall,AndreaJ.;Cassidy,Peter;Alewood,PaulF.[AngewandteChemie-InternationalEdition,2009,vol.48,p.5675-5678][Angew.Chem.,Int.Ed.,2009,vol.121,p.5785-5788]

[19]Locationinpatent:schemeortableGouault,Nicolas;LeRoch,Myriam;Cornee,Carole;David,Michele;Uriac,Philippe[JournalofOrganicChemistry,2009,vol.74,#15,p.5614-5617]

[20]Ueda,Hirofumi;Yamaguchi,Minami;Kameya,Hiroshi;Sugimoto,Kenji;Tokuyama,Hidetoshi[OrganicLetters,2014,vol.16,#18,p.4948-4951]

Literature
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SDS
Tags:121505-94-0 Molecular Formula|121505-94-0 MDL|121505-94-0 SMILES|121505-94-0 N-Alpha-cbz-glycine n-methoxy-n-methylamide