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1215085-92-9,MFCD25976946
Catalog No.:AA009CF8

1215085-92-9 | Glpg0492

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Purity
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1mg
≥98%
in stock  
$549.00   $384.00
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009CF8
Chemical Name:
Glpg0492
CAS Number:
1215085-92-9
Molecular Formula:
C19H14F3N3O3
Molecular Weight:
389.3280
MDL Number:
MFCD25976946
SMILES:
N#Cc1ccc(cc1C(F)(F)F)N1C(=O)N([C@](C1=O)(CO)c1ccccc1)C
Properties
Computed Properties
 
Complexity:
683  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
2.9  

Literature

Title: Nique F, et al. Identification of a 4-(hydroxymethyl)diarylhydantoin as a selective androgen receptor modulator. J Med Chem. 2012 Oct 11;55(19):8236-47.

Title: Cozzoli A, et al. GLPG0492, a novel selective androgen receptor modulator, improves muscle performance in the exercised-mdx mouse model of muscular dystrophy. Pharmacol Res. 2013 Jun;72:9-24.

Title: Blanqué R, et al. Characterization of GLPG0492, a selective androgen receptor modulator, in a mouse model of hindlimb immobilization. BMC Musculoskelet Disord. 2014 Sep 3;15:291.

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SDS
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