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1215493-56-3,MFCD25976845
Catalog No.:AA009CBS

1215493-56-3 | Rg2833

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$7.00   $5.00
- +
5mg
98%
in stock  
$15.00   $11.00
- +
10mg
98%
in stock  
$21.00   $15.00
- +
250mg
95%
in stock  
$189.00   $132.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009CBS
Chemical Name:
Rg2833
CAS Number:
1215493-56-3
Molecular Formula:
C20H25N3O2
Molecular Weight:
339.4314
MDL Number:
MFCD25976845
SMILES:
O=C(Nc1ccccc1N)CCCCCNC(=O)c1ccc(cc1)C
Properties
Computed Properties
 
Complexity:
419  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
8  
XLogP3:
2.8  

Literature

Title: Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model.

Journal: PloS one 20100101

Title: Rai M, et al. Two new pimelic diphenylamide HDAC inhibitors induce sustained frataxin upregulation in cells from Friedreich's ataxia patients and in a mouse model. PLoS One. 2010, 5(1), e8825.

Title: Sandi C, et al. Prolonged treatment with pimelic o-aminobenzamide HDAC inhibitors ameliorates the disease phenotype of a Friedreich ataxia mouse model. Neurobiol Dis. 2011, 42(3), 496-505.

Title: Johnston TH, et al. RGFP109, a histone deacetylase inhibitor attenuates L-DOPA-induced dyskinesia in the MPTP-lesioned marmoset: a proof-of-concept study. Parkinsonism Relat Disord. 2013, 19(2), 260-264.

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SDS
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Tags:1215493-56-3 Molecular Formula|1215493-56-3 MDL|1215493-56-3 SMILES|1215493-56-3 Rg2833