Catalog No.:AA009YW0

1215868-94-2 | AMG-8718

Name: Name:AMG-8718
Brand: AABLOCKS
SKU: AA009YW0
Rating: 90 (10 reviews)

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Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA009YW0

Chemical Name:

AMG-8718

CAS Number:

1215868-94-2

Molecular Formula:

C25H19FN4O3

Molecular Weight:

442.4418

MDL Number:

MFCD28902223

SMILES:

CC1(COC1)C#CC2=CC3=C(N=C2)OC4=C(C35COC(=N5)N)C=C(C=C4)C6=C(N=CC=C6)F

Properties

Literature

Title: Dineen TA,et al. Inhibitors of β-site amyloid precursor protein cleaving enzyme (BACE1): identification of (S)-7-(2-fluoropyridin-3-yl)-3-((3-methyloxetan-3-yl)ethynyl)-5'H-spiro[chromeno,3-bpyridine-5,4'-oxazol-2'-amine (AMG-8718). J Med Chem. 2014 Dec 11;57(23):9811-31.

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