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1219739-36-2,MFCD31696597
Catalog No.:AA01EN3H

1219739-36-2 | Ex229

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
95%
in stock  
$42.00   $30.00
- +
10mg
95%
in stock  
$64.00   $45.00
- +
25mg
95%
in stock  
$108.00   $76.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA01EN3H
Chemical Name:
Ex229
CAS Number:
1219739-36-2
Molecular Formula:
C24H18ClN3O3
Molecular Weight:
431.8710
MDL Number:
MFCD31696597
SMILES:
Clc1cc2nc([nH]c2cc1c1ccc2c(c1)ccn2C)Oc1ccc(c(c1)C(=O)O)C
Properties

Downstream Synthesis Route
Methyl5-6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yloxy}-2-methylbenzoate 
  1219739-36-2 

[1]CurrentPatentAssignee:MERCK&COINC-US2010/81643,2010,A1Locationinpatent:Page/Pagecolumn101

[2]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

[1]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

[1]JournalofMedicinalChemistry,2017,vol.60,p.9040-9052

[1]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

[1]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

Literature

Title: Xiao B, et al. Structural basis of AMPK regulation by small molecule activators. Nat Commun. 2013;4:3017.

Title: Bultot L, et al. Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle. Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E706-E719.

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SDS
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Tags:1219739-36-2 Molecular Formula|1219739-36-2 MDL|1219739-36-2 SMILES|1219739-36-2 Ex229
Catalog No.: AA01EN3H
1219739-36-2,MFCD31696597
1219739-36-2 | Ex229
Pack Size： 5mg
Purity： 95%
in stock
$42.00 $30.00
Pack Size： 10mg
Purity： 95%
in stock
$64.00 $45.00
Pack Size： 25mg
Purity： 95%
in stock
$108.00 $76.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA01EN3H
Chemical Name: Ex229
CAS Number: 1219739-36-2
Molecular Formula: C24H18ClN3O3
Molecular Weight: 431.8710
MDL Number: MFCD31696597
SMILES: Clc1cc2nc([nH]c2cc1c1ccc2c(c1)ccn2C)Oc1ccc(c(c1)C(=O)O)C
Properties
Downstream Synthesis Route
Methyl5-6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yloxy}-2-methylbenzoate 
  1219739-36-2 

[1]CurrentPatentAssignee:MERCK&COINC-US2010/81643,2010,A1Locationinpatent:Page/Pagecolumn101

[2]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

1635-61-6    1219739-36-2 

[1]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

335349-57-0    1219739-36-2 

[1]JournalofMedicinalChemistry,2017,vol.60,p.9040-9052

1219741-20-4    1219739-36-2 

[1]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

1219741-21-5    1219739-36-2 

[1]Lan,Ping;Romero,F.Anthony;Wodka,Dariusz;Kassick,AndrewJ.;Dang,Qun;Gibson,Tony;Cashion,Daniel;Zhou,Gaochao;Chen,Yuli;Zhang,Xiaoping;Zhang,Aihua;Li,Ying;Trujillo,MariaE.;Shao,Qing;Wu,Margaret;Xu,Shiyao;He,Huaibing;Mackenna,Deidre;Staunton,Jocelyn;Chapman,KevinT.;Weber,Ann;Sebhat,IyassuK.;Makara,GergelyM.[JournalofMedicinalChemistry,2017,vol.60,#21,p.9040-9052]

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309288-92-4
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57294-98-1
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32630-92-5
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