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1222800-79-4,MFCD28053518
Catalog No.:AA0016YY

1222800-79-4 | Ml324

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$46.00   $32.00
- +
5mg
≥95%
in stock  
$100.00   $70.00
- +
10mg
≥95%
in stock  
$156.00   $109.00
- +
25mg
98%
in stock  
$259.00   $182.00
- +
100mg
98%
in stock  
$656.00   $459.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0016YY
Chemical Name:
Ml324
CAS Number:
1222800-79-4
Molecular Formula:
C21H23N3O2
Molecular Weight:
349.4262
MDL Number:
MFCD28053518
SMILES:
CN(CCCNC(=O)c1ccc(cc1)c1cc(O)c2c(c1)cccn2)C
Properties
Computed Properties
 
Complexity:
449  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
3.1  

Literature

Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.

Journal: Bioorganic & medicinal chemistry letters 20130801

Title: Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

Journal: Cell 20060505

Title: Rai G, et al. Discovery of ML324, a JMJD2 demethylase inhibitor with demonstrated antiviral activity.

Title: Joy E. Kirkpatrick, et al. Inhibition of the histone demethylase KDM4B leads to activation of KDM1A, attenuates bacterial-induced pro-inflammatory cytokine release, and reduces osteoclastogenesis. Epigenetics. 2018; 13(5): 557–572.

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SDS
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