Home Thiazoles 1226056-71-8
1226056-71-8,MFCD16495823
Catalog No.:AA0017GM

1226056-71-8 | Thiazovivin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$25.00   $18.00
- +
5mg
98+%
in stock  
$41.00   $29.00
- +
100mg
99%(HPLC)
in stock  
$207.00   $145.00
- +
250mg
98+%
in stock  
$217.00   $152.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0017GM
Chemical Name:
Thiazovivin
CAS Number:
1226056-71-8
Molecular Formula:
C15H13N5OS
Molecular Weight:
311.3616
MDL Number:
MFCD16495823
SMILES:
O=C(c1csc(n1)Nc1ccncn1)NCc1ccccc1
Properties
Computed Properties
 
Complexity:
364  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
2.5  

Upstream Synthesis Route

[1]SyntheticCommunications,2013,vol.43,#21,p.2876-2882

Literature

Title: Resveratrol prevents AngII-induced hypertension via AMPK activation and RhoA/ROCK suppression in mice.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20140901

Title: Direct conversion of porcine embryonic fibroblasts into adipocytes by chemical molecules.

Journal: Cellular reprogramming 20120401

Title: A chemical platform for improved induction of human iPSCs.

Journal: Nature methods 20091101

Title: Xu Y, et al. Revealing a core signaling regulatory mechanism for pluripotent stem cell survival and self-renewal by small molecules. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8129-34.

Title: Park S, et al. Thiazovivin, a Rho kinase inhibitor, improves stemness maintenance of embryo-derived stem-like cells under chemically defined culture conditions in cattle. Anim Reprod Sci. 2015 Oct;161:47-57.

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SDS
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