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1228111-63-4
Catalog No.:AA01NCBV

1228111-63-4 | PF-04634817

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
>98.00%
3 weeks  
$418.00   $293.00
- +
5mg
>98.00%
3 weeks  
$667.00   $467.00
- +
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Technical Information
Catalog Number:
AA01NCBV
Chemical Name:
PF-04634817
CAS Number:
1228111-63-4
Molecular Formula:
C25H36F3N5O3
Molecular Weight:
511.5802
SMILES:
CC(C)C1(CCC(C1)NC2CCOCC2OC)C(=O)N3CC4CC3CN4C5=NC=NC(=C5)C(F)(F)F
Properties

Literature

Title: Tesch GH, et al. Combined inhibition of CCR2 and ACE provides added protection against progression of diabetic nephropathy in Nos3-deficient mice.Am J Physiol Renal Physiol. 2019 Dec 1;317(6):F1439-F1449.

Title: Gale JD, et al. A CCR2/5 Inhibitor, PF-04634817, Is Inferior to Monthly Ranibizumab in the Treatment of Diabetic Macular Edema. Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2659-2669.

Title: Gale JD, et al. Effect of PF-04634817, an Oral CCR2/5 Chemokine Receptor Antagonist, on Albuminuria in Adults with Overt Diabetic Nephropathy. Kidney Int Rep. 2018 Aug 3;3(6):1316-1327.

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