+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Amines 1234480-46-6
1234480-46-6,MFCD30742941
Catalog No.:AA000KI6

1234480-46-6 | 6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$22.00   $15.00
- +
5mg
97%
in stock  
$74.00   $52.00
- +
10mg
97%
in stock  
$140.00   $98.00
- +
25mg
97%
in stock  
$321.00   $225.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000KI6
Chemical Name:
6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-
CAS Number:
1234480-46-6
Molecular Formula:
C24H27N7O2
Molecular Weight:
445.5169
MDL Number:
MFCD30742941
SMILES:
COc1cc(ccc1Nc1ncc2c(n1)n(C)c1ccccc1c(=O)[nH]2)N1CCN(CC1)C
Properties
Computed Properties
 
Complexity:
673  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
2.9  

Downstream Synthesis Route

[1]Chen,Bailing;Feru,Frederic;Feutrill,John;Gero,ThomasW.;Gray,NathanaelS.;Groendyke,BrianJ.;Li,Bin;Li,Zhengnian;Pang,Kevin;Powell,ChelseaE.;Scott,DavidA.;Szabo,Hilary[BioorganicandMedicinalChemistryLetters,2020,vol.30,#4]

[2]Locationinpatent:schemeortableDeng,Xianming;Yang,Qingkai;Kwiatkowski,Nicholas;Sim,Taebo;McDermott,Ultan;Settleman,JeffreyE.;Lee,Jiing-Dwan;Gray,NathanaelS.[ACSMedicinalChemistryLetters,2011,vol.2,#3,p.195-200]

[1]Deng,Xianming;Yang,Qingkai;Kwiatkowski,Nicholas;Sim,Taebo;McDermott,Ultan;Settleman,JeffreyE.;Lee,Jiing-Dwan;Gray,NathanaelS.[ACSMedicinalChemistryLetters,2011,vol.2,#3,p.195-200]

[2]Chen,Bailing;Feru,Frederic;Feutrill,John;Gero,ThomasW.;Gray,NathanaelS.;Groendyke,BrianJ.;Li,Bin;Li,Zhengnian;Pang,Kevin;Powell,ChelseaE.;Scott,DavidA.;Szabo,Hilary[BioorganicandMedicinalChemistryLetters,2020,vol.30,#4]

[1]ACSMedicinalChemistryLetters,2011,vol.2,p.195-200

Literature

Title: Maxson JE, et al. Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1234480-46-6
1234480-50-2

1234480-50-2

 2222635-15-4

2222635-15-4

 2108526-77-6

2108526-77-6
Building Blocks
More >
Tags:1234480-46-6 Molecular Formula|1234480-46-6 MDL|1234480-46-6 SMILES|1234480-46-6 6H-Pyrimido[4,5-b][1,4]benzodiazepin-6-one, 5,11-dihydro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-11-methyl-