Catalog No.:AA01XGWN

1234510-46-3 | TRV-120027

Name: Name:TRV-120027
Brand: AABLOCKS
SKU: AA01XGWN
Availability: InStock
Rating: 90 (10 reviews)

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1mg

99%

1 week

$177.00 $124.00

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5mg

99%

1 week

$447.00 $313.00

- +

10mg

99%

1 week

$685.00 $480.00

- +

Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA01XGWN

Chemical Name:

TRV-120027

CAS Number:

1234510-46-3

Molecular Formula:

C43H67N13O10

Molecular Weight:

926.0732

SMILES:

CNCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(=O)O)C)Cc1nc[nH]c1)[C@H](CC)C)Cc1ccc(cc1)O)C(C)C)CCCNC(=N)N

Properties

Literature

Title: Boerrigter G, et al. TRV120027, a novel β-arrestin biased ligand at the angiotensin II type I receptor, unloads the heart and maintains renal function when added to furosemide in experimental heart failure.Circ Heart Fail. 2012 Sep 1;5(5):627-34. Epub 2012 Aug 13.

Title: Liu CH, et al. Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling.Nat Commun. 2017 Feb 9;8:14335.

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