Name: Name:2(1H)-Isoquinolinecarboxylic acid, 8-[(2-benzothiazolylamino)carbonyl]-3,4-dihydro-, 1,1-dimethylethyl ester
Brand: AABLOCKS
SKU: AA009CJW
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA009CJW

Chemical Name: 2(1H)-Isoquinolinecarboxylic acid, 8-[(2-benzothiazolylamino)carbonyl]-3,4-dihydro-, 1,1-dimethylethyl ester

CAS Number: 1235034-71-5

Molecular Formula: C22H23N3O3S

Molecular Weight: 409.5013

MDL Number: MFCD30491841

SMILES: O=C(N1CCc2c(C1)c(ccc2)C(=O)Nc1nc2c(s1)cccc2)OC(C)(C)C

Properties

Downstream Synthesis Route

136-95-8

878798-87-9

1235034-71-5

[1]Tao,Zhi-Fu;Hasvold,Lisa;Wang,Le;Wang,Xilu;Petros,AndrewM.;Park,ChangH.;Boghaert,ErwinR.;Catron,NathanielD.;Chen,Jun;Colman,PeterM.;Czabotar,PeterE.;Deshayes,Kurt;Fairbrother,WayneJ.;Flygare,JohnA.;Hymowitz,SarahG.;Jin,Sha;Judge,RussellA.;Koehler,MichaelF.T.;Kovar,PeterJ.;Lessene,Guillaume;Mitten,MichaelJ.;Ndubaku,ChudiO.;Nimmer,Paul;Purkey,HansE.;Oleksijew,Anatol;Phillips,DarrenC.;Sleebs,BradE.;Smith,BrianJ.;Smith,MoreyL.;Tahir,StephenK.;Watson,KeithG.;Xiao,Yu;Xue,John;Zhang,Haichao;Zobel,Kerry;Rosenberg,SaulH.;Tse,Chris;Leverson,JoelD.;Elmore,StevenW.;Souers,AndrewJ.[ACSMedicinalChemistryLetters,2014,vol.5,#10,p.1088-1093]

[2]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2010/80503,2010,A1Locationinpatent:Page/Pagecolumn87-88

[3]CurrentPatentAssignee:POTISEKSTEPHANIEL;ABBVIEINC-US2013/96120,2013,A1Locationinpatent:Paragraph0876

[4]CurrentPatentAssignee:POTISEKSTEPHANIEL;ABBVIEINC-US2013/96121,2013,A1Locationinpatent:Paragraph1222

[5]CurrentPatentAssignee:ABBVIEINC-WO2014/28381,2014,A1Locationinpatent:Page/Pagecolumn111

[6]Koehler,MichaelF.T.;Bergeron,Philippe;Choo,EdnaF.;Lau,Kevin;Ndubaku,Chudi;Dudley,Danette;Gibbons,Paul;Sleebs,BradE.;Rye,CarlS.;Nikolakopoulos,George;Bui,Chinh;Kulasegaram,Sanji;Kersten,WilhelmusJ.A.;Smith,BrianJ.;Czabotar,PeterE.;Colman,PeterM.;Huang,DavidC.S.;Baell,JonathanB.;Watson,KeithG.;Hasvold,Lisa;Tao,Zhi-Fu;Wang,Le;Souers,AndrewJ.;Elmore,StevenW.;Flygare,JohnA.;Fairbrother,WayneJ.;Lessene,Guillaume[ACSMedicinalChemistryLetters,2014,vol.5,#6,p.662-667]

[7]CurrentPatentAssignee:ABBVIEINC-WO2016/94505,2016,A1Locationinpatent:Paragraph000384

[8]CurrentPatentAssignee:ABBVIEINC-WO2017/214456,2017,A1Locationinpatent:Page/Pagecolumn279

[9]CurrentPatentAssignee:ABBVIEINC-US2019/153107,2019,A1Locationinpatent:Paragraph0861

1235034-71-5 | 2(1H)-Isoquinolinecarboxylic acid, 8-[(2-benzothiazolylamino)carbonyl]-3,4-dihydro-, 1,1-dimethylethyl ester