Name: Name:tert-Butyl 6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1h)-yl)-3-bromopicolinate
Brand: AABLOCKS
SKU: AA000KMB
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA000KMB

Chemical Name: tert-Butyl 6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1h)-yl)-3-bromopicolinate

CAS Number: 1235036-16-4

Molecular Formula: C27H25BrN4O3S

Molecular Weight: 565.4814

MDL Number: MFCD25542407

SMILES: O=C(c1cccc2c1CN(CC2)c1ccc(c(n1)C(=O)OC(C)(C)C)Br)Nc1nc2c(s1)cccc2

Properties

Downstream Synthesis Route

1235036-15-3

N-(benzodthiazol-2-yl)-1,2,3,4-tetrahydroisoquinoline-8-carboxamidedihydrochloride

1235036-16-4

[1]Patent:WO2010/80503,2010,A1.Locationinpatent:Page/Pagecolumn199-200

[2]Patent:WO2010/80503,2010,A1.Locationinpatent:Page/Pagecolumn233

[3]ACSMedicinalChemistryLetters,2014,vol.5,p.662-667

[4]Patent:US2013/96120,2013,A1.Locationinpatent:Paragraph0879;0880

[5]Patent:US2013/96121,2013,A1.Locationinpatent:Paragraph1225

[6]Patent:WO2014/28381,2014,A1.Locationinpatent:Page/Pagecolumn112

761446-45-1

1235036-16-4

1430750-27-8

[1]Patent:US2013/96121,2013,A1.Locationinpatent:Paragraph1226

929000-66-8

1235036-16-4

[1]Patent:US2013/96120,2013,A1

[2]Patent:US2013/96121,2013,A1

[3]Patent:WO2014/28381,2014,A1

[4]ACSMedicinalChemistryLetters,2014,vol.5,p.662-667

878798-87-9

1235036-16-4

[1]CurrentPatentAssignee:POTISEKSTEPHANIEL;ABBVIEINC-US2013/96121,2013,A1

[2]CurrentPatentAssignee:ABBVIEINC-WO2014/28381,2014,A1

[3]Koehler,MichaelF.T.;Bergeron,Philippe;Choo,EdnaF.;Lau,Kevin;Ndubaku,Chudi;Dudley,Danette;Gibbons,Paul;Sleebs,BradE.;Rye,CarlS.;Nikolakopoulos,George;Bui,Chinh;Kulasegaram,Sanji;Kersten,WilhelmusJ.A.;Smith,BrianJ.;Czabotar,PeterE.;Colman,PeterM.;Huang,DavidC.S.;Baell,JonathanB.;Watson,KeithG.;Hasvold,Lisa;Tao,Zhi-Fu;Wang,Le;Souers,AndrewJ.;Elmore,StevenW.;Flygare,JohnA.;Fairbrother,WayneJ.;Lessene,Guillaume[ACSMedicinalChemistryLetters,2014,vol.5,#6,p.662-667]

[4]CurrentPatentAssignee:ABBVIEINC-WO2016/94505,2016,A1

[5]CurrentPatentAssignee:ABBVIEINC-WO2017/214456,2017,A1CurrentPatentAssignee:ABBVIEINC-US2019/153107,2019,A1

1211589-43-3

1235036-16-4

[1]Patent:WO2016/94505,2016,A1

[2]Patent:WO2017/214456,2017,A1

[3]Patent:US2019/153107,2019,A1

1235036-16-4 | tert-Butyl 6-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1h)-yl)-3-bromopicolinate