+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Other Building Blocks 1235403-62-9
1235403-62-9,MFCD28900736
Catalog No.:AA000KOS

1235403-62-9 | PF-05089771

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$73.00   $51.00
- +
5mg
98%
in stock  
$155.00   $109.00
- +
25mg
98% by HPLC
in stock  
$637.00   $446.00
- +
50mg
98% by HPLC
in stock  
$1,040.00   $728.00
- +
100mg
98% by HPLC
in stock  
$1,752.00   $1,227.00
- +
500mg
98% by HPLC
in stock  
$5,515.00   $3,861.00
- +
1000mg
98% by HPLC
in stock  
$8,787.00   $6,151.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000KOS
Chemical Name:
PF-05089771
CAS Number:
1235403-62-9
Molecular Formula:
C18H12Cl2FN5O3S2
Molecular Weight:
500.3540
MDL Number:
MFCD28900736
SMILES:
Clc1ccc(c(c1)c1c[nH]nc1N)Oc1cc(F)c(cc1Cl)S(=O)(=O)Nc1cscn1
Properties
Computed Properties
 
Complexity:
721  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
6  
XLogP3:
4.3  

Downstream Synthesis Route

[1]Patent:CN106243003,2016,A

[1]Patent:CN106243003,2016,A

Literature

Title: Alexandrou AJ, et al. Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release. PLoS One. 2016 Apr 6;11(4):e0152405.

Title: Theile JW, et al. The Selective Nav1.7 Inhibitor, PF-05089771, Interacts Equivalently with Fast and Slow Inactivated Nav1.7 Channels. Mol Pharmacol. 2016 Nov;90(5):540-548.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1235403-62-9
1430806-04-4

1430806-04-4
Building Blocks
More >
Tags:1235403-62-9 Molecular Formula|1235403-62-9 MDL|1235403-62-9 SMILES|1235403-62-9 PF-05089771