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1239875-86-5,MFCD28963942
Catalog No.:AA000L88

1239875-86-5 | SGI-7079

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$42.00   $29.00
- +
2mg
98+%
in stock  
$70.00   $49.00
- +
25mg
≥98%
in stock  
$652.00   $456.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000L88
Chemical Name:
SGI-7079
CAS Number:
1239875-86-5
Molecular Formula:
C26H26FN7
Molecular Weight:
455.5299
MDL Number:
MFCD28963942
SMILES:
N#CCc1cccc(c1)c1nc(Nc2ccc(c(c2)F)N2CCN(CC2)C)nc2c1c(C)c[nH]2
Properties
Computed Properties
 
Complexity:
719  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
4.3  

Downstream Synthesis Route
Literature

Title: Wang X, et al. TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase. Cancer Res. 2013 Nov 1;73(21):6516-25.

Title: Byers LA, et al. An epithelial-mesenchymal transition gene signature predicts resistance to EGFR and PI3K inhibitors and identifies Axl as a therapeutic target for overcoming EGFR inhibitor resistance. Clin Cancer Res. 2013 Jan 1;19(1):279-90.

Title: Chenjing Zhu, et al. AXL receptor tyrosine kinase as a promising anti-cancer approach: functions, molecular mechanisms and clinical applications. Mol Cancer. 2019 Nov 4;18(1):153.

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Additional Info:
SDS
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