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Home Other Building Blocks 1242137-16-1
1242137-16-1,MFCD24386671
Catalog No.:AA009CB1

1242137-16-1 | N-desmethyl Enzalutamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
95%
in stock  
$129.00   $90.00
- +
10mg
95%
in stock  
$180.00   $126.00
- +
50mg
95%
in stock  
$720.00   $504.00
- +
100mg
98%
in stock  
$1,218.00   $853.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA009CB1
Chemical Name:
N-desmethyl Enzalutamide
CAS Number:
1242137-16-1
Molecular Formula:
C20H14F4N4O2S
Molecular Weight:
450.4094
MDL Number:
MFCD24386671
SMILES:
N#Cc1ccc(cc1C(F)(F)F)N1C(=S)N(C(C1=O)(C)C)c1ccc(c(c1)F)C(=O)N
Properties
Computed Properties
 
Complexity:
824  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
3.2  

Downstream Synthesis Route

[1]CurrentPatentAssignee:PFIZERINC-WO2010/99238,2010,A1Locationinpatent:Page/Pagecolumn34-35

[1]CurrentPatentAssignee:PFIZERINC-WO2010/99238,2010,A1Locationinpatent:Page/Pagecolumn35

[1]Zhou,Ai-Nan;Li,Bonan;Ruan,Lejun;Wang,Yeting;Duan,Gengli;Li,Jianqi[ChineseChemicalLetters,2017,vol.28,#2,p.426-430]

[1]Zhou,Ai-Nan;Li,Bonan;Ruan,Lejun;Wang,Yeting;Duan,Gengli;Li,Jianqi[ChineseChemicalLetters,2017,vol.28,#2,p.426-430]

2-((3-fluoro-4-(methoxycarbonyl)phenyl)amino)-2-methylpropanoicacid 
  1242137-16-1 

[1]Zhou,Ai-Nan;Li,Bonan;Ruan,Lejun;Wang,Yeting;Duan,Gengli;Li,Jianqi[ChineseChemicalLetters,2017,vol.28,#2,p.426-430]

Literature

Title: Gibbons JA, et al. Pharmacokinetic Drug Interaction Studies with Enzalutamide. Clin Pharmacokinet. 2015 Oct;54(10):1057-69.

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SDS
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