Home Other Building Blocks 125256-00-0
125256-00-0,MFCD02376000
Catalog No.:AA000NB8

125256-00-0 | Fatostatin

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$19.00   $14.00
- +
5mg
98%
in stock  
$54.00   $38.00
- +
10mg
98%
in stock  
$85.00   $60.00
- +
25mg
98%
in stock  
$135.00   $95.00
- +
100mg
98%
in stock  
$261.00   $183.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA000NB8
Chemical Name:
Fatostatin
CAS Number:
125256-00-0
Molecular Formula:
C18H18N2S
Molecular Weight:
294.4139
MDL Number:
MFCD02376000
SMILES:
CCCc1nccc(c1)c1scc(n1)c1ccc(cc1)C
Properties
Computed Properties
 
Complexity:
314  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
3  
Rotatable Bond Count:
4  
XLogP3:
4.8  

Downstream Synthesis Route

[1]Tani,Satoshi;Uehara,TakahiroN.;Yamaguchi,Junichiro;Itami,Kenichiro[ChemicalScience,2013,vol.5,#1,p.123-135]

C23H19NOS 
  125256-00-0 

[1]Tani,Satoshi;Uehara,TakahiroN.;Yamaguchi,Junichiro;Itami,Kenichiro[ChemicalScience,2013,vol.5,#1,p.123-135]

[1]Tani,Satoshi;Uehara,TakahiroN.;Yamaguchi,Junichiro;Itami,Kenichiro[ChemicalScience,2013,vol.5,#1,p.123-135]

[1]JournalofMedicinalChemistry,2014,vol.57,p.6572-6582

[1]Bellale,Eknath;Naik,Maruti;Vb,Varun;Ambady,Anisha;Narayan,Ashwini;Ravishankar,Sudha;Ramachandran,Vasanthi;Kaur,Parvinder;McLaughlin,Robert;Whiteaker,James;Morayya,Sapna;Guptha,Supreeth;Sharma,Sreevalli;Raichurkar,Anandkumar;Awasthy,Disha;Achar,Vijayshree;Vachaspati,Prakash;Bandodkar,Balachandra;Panda,Manoranjan;Chatterji,Monalisa[JournalofMedicinalChemistry,2014,vol.57,#15,p.6572-6582]

Literature

Title: An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer.

Journal: Nature genetics 20180201

Title: Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins.

Journal: Journal of medicinal chemistry 20110714

Title: A small molecule that blocks fat synthesis by inhibiting the activation of SREBP.

Journal: Chemistry & biology 20090828

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SDS
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