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1254053-84-3,MFCD28386208
Catalog No.:AA000NJW

1254053-84-3 | 2-Pyrazinecarboxamide, 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-, (2E)-2-butenedioate (2:1)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$96.00   $68.00
- +
5mg
95%
1 week  
$149.00   $104.00
- +
10mg
95%
1 week  
$197.00   $138.00
- +
25mg
95%
1 week  
$284.00   $199.00
- +
50mg
95%
1 week  
$388.00   $272.00
- +
100mg
95%
1 week  
$578.00   $404.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA000NJW
Chemical Name:
2-Pyrazinecarboxamide, 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-, (2E)-2-butenedioate (2:1)
CAS Number:
1254053-84-3
Molecular Formula:
C62H92N16O10
Molecular Weight:
1221.4951
MDL Number:
MFCD28386208
SMILES:
OC(=O)/C=C/C(=O)O.COc1cc(ccc1N1CCC(CC1)N1CCN(CC1)C)Nc1nc(NC2CCOCC2)c(nc1C(=O)N)CC.COc1cc(ccc1N1CCC(CC1)N1CCN(CC1)C)Nc1nc(NC2CCOCC2)c(nc1C(=O)N)CC
Properties
Computed Properties
 
Complexity:
904  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
1  
Formal Charge:
0  
Heavy Atom Count:
88  
Hydrogen Bond Acceptor Count:
24  
Hydrogen Bond Donor Count:
8  
Isotope Atom Count:
0  
Rotatable Bond Count:
20  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  

Literature

Title: ASP2215, a novel FLT3/AXL inhibitor: Preclinical evaluation in acute myeloid leukemia (AML). 2014 ASCO Annual Meeting.

Title: Mori M, et al. Gilteritinib, a FLT3/AXL inhibitor, shows antileukemic activity in mouse models of FLT3 mutated acute myeloid leukemia. Invest New Drugs. 2017 Oct;35(5):556-565.

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SDS
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Tags:1254053-84-3 Molecular Formula|1254053-84-3 MDL|1254053-84-3 SMILES|1254053-84-3 2-Pyrazinecarboxamide, 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-, (2E)-2-butenedioate (2:1)
Catalog No.: AA000NJW
1254053-84-3,MFCD28386208
1254053-84-3 | 2-Pyrazinecarboxamide, 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-, (2E)-2-butenedioate (2:1)
Pack Size： 1mg
Purity： 95%
1 week
$96.00 $68.00
Pack Size： 5mg
Purity： 95%
1 week
$149.00 $104.00
Pack Size： 10mg
Purity： 95%
1 week
$197.00 $138.00
Pack Size： 25mg
Purity： 95%
1 week
$284.00 $199.00
Pack Size： 50mg
Purity： 95%
1 week
$388.00 $272.00
Pack Size： 100mg
Purity： 95%
1 week
$578.00 $404.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA000NJW
Chemical Name: 2-Pyrazinecarboxamide, 6-ethyl-3-[[3-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]amino]-5-[(tetrahydro-2H-pyran-4-yl)amino]-, (2E)-2-butenedioate (2:1)
CAS Number: 1254053-84-3
Molecular Formula: C62H92N16O10
Molecular Weight: 1221.4951
MDL Number: MFCD28386208
SMILES: OC(=O)/C=C/C(=O)O.COc1cc(ccc1N1CCC(CC1)N1CCN(CC1)C)Nc1nc(NC2CCOCC2)c(nc1C(=O)N)CC.COc1cc(ccc1N1CCC(CC1)N1CCN(CC1)C)Nc1nc(NC2CCOCC2)c(nc1C(=O)N)CC
Properties
Complexity: 904  
Covalently-Bonded Unit Count: 3  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 1  
Formal Charge: 0  
Heavy Atom Count: 88  
Hydrogen Bond Acceptor Count: 24  
Hydrogen Bond Donor Count: 8  
Isotope Atom Count: 0  
Rotatable Bond Count: 20  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
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