Home Other Building Blocks 1259389-38-2
1259389-38-2,MFCD28167803
Catalog No.:AA009C68

1259389-38-2 | AMG 837 (calciuM hydrate)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$99.00   $69.00
- +
2mg
95%
1 week  
$116.00   $81.00
- +
5mg
95%
1 week  
$149.00   $104.00
- +
10mg
95%
1 week  
$197.00   $138.00
- +
25mg
95%
1 week  
$351.00   $246.00
- +
50mg
95%
1 week  
$644.00   $451.00
- +
100mg
95%
1 week  
$891.00   $624.00
- +
200mg
95%
1 week  
$1,195.00   $836.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009C68
Chemical Name:
AMG 837 (calciuM hydrate)
CAS Number:
1259389-38-2
Molecular Formula:
C52H42CaF6O7
Molecular Weight:
932.9541
MDL Number:
MFCD28167803
SMILES:
CC#CC(CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC=CC(=C2)C3=CC=C(C=C3)C(F)(F)F.CC#CC(CC(=O)[O-])C1=CC=C(C=C1)OCC2=CC=CC(=C2)C3=CC=C(C=C3)C(F)(F)F.O.[Ca+2]
Properties
Computed Properties
 
Complexity:
655  
Covalently-Bonded Unit Count:
4  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
66  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
12  

Literature

Title: Daniel CHL, et, al. AMG 837: a novel GPR40/FFA1 agonist that enhances insulin secretion and lowers glucose levels in rodents. PLoS One. 2011; 6(11): e27270.

Title: Houze JB, et, al. AMG 837: a potent, orally bioavailable GPR40 agonist. Bioorg Med Chem Lett. 2012 Jan 15; 22(2): 1267-70.

Title: Daniel CHL, et, al. Identification and pharmacological characterization of multiple allosteric binding sites on the free fatty acid 1 receptor. Mol Pharmacol. 2012 Nov;82(5):843-59.

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SDS
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Tags:1259389-38-2 Molecular Formula|1259389-38-2 MDL|1259389-38-2 SMILES|1259389-38-2 AMG 837 (calciuM hydrate)