Home Other Building Blocks 125995-03-1
125995-03-1,MFCD00899262
Catalog No.:AA000QKT

125995-03-1 | Atorvastatin lactone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$46.00   $32.00
- +
5mg
95%
in stock  
$116.00   $81.00
- +
10mg
95%
in stock  
$180.00   $126.00
- +
25mg
≥95%
in stock  
$382.00   $267.00
- +
100mg
>95.0%(HPLC)
in stock  
$414.00   $290.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000QKT
Chemical Name:
Atorvastatin lactone
CAS Number:
125995-03-1
Molecular Formula:
C33H33FN2O4
Molecular Weight:
540.6245
MDL Number:
MFCD00899262
SMILES:
O[C@@H]1C[C@@H](CCn2c(C(C)C)c(c(c2c2ccc(cc2)F)c2ccccc2)C(=O)Nc2ccccc2)OC(=O)C1
Properties
Computed Properties
 
Complexity:
834  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
40  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  
XLogP3:
5.7  

Literature

Title: Evaluation of the anti-HIV activity of statins.

Journal: AIDS (London, England) 20051014

Title: Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20050401

Title: Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[2-(1H-pyrrol-1-yl)ethyl]-2H-pyran-2-one inhibitors of HMG-CoA reductase. 2. Effects of introducing substituents at positions three and four of the pyrrole nucleus.

Journal: Journal of medicinal chemistry 19910101

Title: Valesky RJ, et al. Automated enzyme inhibition assay method for the determination of atorvastatin-derived HMG-CoA reductase inhibitors in human plasma using radioactivity detection. J Pharmacol Toxicol Methods. 2008 Jan-Feb;57(1):61-9.

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SDS
Tags:125995-03-1 Molecular Formula|125995-03-1 MDL|125995-03-1 SMILES|125995-03-1 Atorvastatin lactone