Home Other Building Blocks 1263273-14-8
1263273-14-8,MFCD26142602
Catalog No.:AA01EOJI

1263273-14-8 | (1R,2S)-VU0155041

Pack Size
Purity
Availability
Price(USD)
Quantity
  
2mg
95%
1 week  
$104.00   $73.00
- +
5mg
95%
1 week  
$134.00   $94.00
- +
10mg
95%
1 week  
$170.00   $119.00
- +
25mg
95%
1 week  
$306.00   $214.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01EOJI
Chemical Name:
(1R,2S)-VU0155041
CAS Number:
1263273-14-8
Molecular Formula:
C14H15Cl2NO3
Molecular Weight:
316.1798
MDL Number:
MFCD26142602
SMILES:
O=C([C@H]1CCCC[C@H]1C(=O)O)Nc1cc(Cl)cc(c1)Cl
Properties
Computed Properties
 
Complexity:
367  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
3.4  

Literature

Title: Selective activation of group III metabotropic glutamate receptor subtypes produces different patterns of γ-aminobutyric acid immunoreactivity and glutamate release in the retina.

Journal: Journal of neuroscience research 20121201

Title: Allosteric modulation of the group III mGlu4 receptor provides functional neuroprotection in the 6-hydroxydopamine rat model of Parkinson's disease.

Journal: British journal of pharmacology 20120801

Title: Measures of anxiety, sensorimotor function, and memory in male and female mGluR4⁻/⁻ mice.

Journal: Behavioural brain research 20120401

Title: Opposing roles of mGluR8 in measures of anxiety involving non-social and social challenges.

Journal: Behavioural brain research 20110801

Title: Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators.

Journal: Journal of medicinal chemistry 20110728

Title: Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.

Journal: Molecular pharmacology 20081101

Title: Niswender CM, et al. Discovery, characterization, and antiparkinsonian effect of novel positiveallosteric modulators of metabotropic glutamate receptor 4. Mol Pharmacol. 2008 Nov;74(5):1345-58.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:1263273-14-8 Molecular Formula|1263273-14-8 MDL|1263273-14-8 SMILES|1263273-14-8 (1R,2S)-VU0155041