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1264-62-6,MFCD00084692
Catalog No.:AA000SO1

1264-62-6 | Erythromycin, 2'-(ethyl butanedioate)

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1g
98%(HPLC)
in stock  
$48.00   $34.00
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5g
98%(HPLC)
in stock  
$115.00   $80.00
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25g
98%(HPLC)
in stock  
$445.00   $312.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000SO1
Chemical Name:
Erythromycin, 2'-(ethyl butanedioate)
CAS Number:
1264-62-6
Molecular Formula:
C43H75NO16
Molecular Weight:
862.0527
MDL Number:
MFCD00084692
SMILES:
CCOC(=O)CCC(=O)OC1C(OC(CC1N(C)C)C)OC1C(C)C(OC2OC(C)C(C(C2)(C)OC)O)C(C)C(=O)OC(CC)C(C(C(C(=O)C(CC1(C)O)C)C)O)(C)O
NSC Number:
756758
Properties
Computed Properties
 
Complexity:
1450  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
18  
Heavy Atom Count:
60  
Hydrogen Bond Acceptor Count:
17  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
14  
XLogP3:
3.4  

Literature

Title: Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models.

Journal: Toxicology and applied pharmacology 20170301

Title: Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action.

Journal: PloS one 20140101

Title: Effects of curcumin on the pharmacokinetics of tamoxifen and its active metabolite, 4-hydroxytamoxifen, in rats: possible role of CYP3A4 and P-glycoprotein inhibition by curcumin.

Journal: Die Pharmazie 20120201

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Sensitive determination of tilmicosin, erythromycin ethylsuccinate and clindamycin by CE with electrochemiluminescence detection using azithromycin as internal standard and its applications.

Journal: Journal of separation science 20100501

Title: Comparison of the effect of azithromycin versus erythromycin on antroduodenal pressure profiles of patients with chronic functional gastrointestinal pain and gastroparesis.

Journal: Digestive diseases and sciences 20100301

Title: [Specific ototoxic effects of monomycin in immature animals].

Journal: Vestnik otorinolaringologii 20090101

Title: Pharmacokinetics of erythromycin after the administration of intravenous and various oral dosage forms to dogs.

Journal: Journal of veterinary pharmacology and therapeutics 20081201

Title: Multiple aphthoid syphilitic chancres of the oral cavity.

Journal: International journal of STD & AIDS 20080701

Title: Familial cases presenting very early onset autosomal dominant Alzheimer's disease with I143T in presenilin-1 gene: implication for genotype-phenotype correlation.

Journal: Neurogenetics 20080201

Title: SCN5A R1193Q polymorphism associated with progressive cardiac conduction defects and long QT syndrome in a Chinese family.

Journal: Journal of medical genetics 20080201

Title: [Erythromycin ethylsuccinate obtaining possibilities].

Journal: Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20080101

Title: Femtosecond IR spectroscopy of peroxycarbonate photodecomposition: S1-lifetime determines decarboxylation rate.

Journal: The journal of physical chemistry. A 20071011

Title: Mechanism for the degradation of erythromycin A and erythromycin A 2'-ethyl succinate in acidic aqueous solution.

Journal: The journal of physical chemistry. A 20071011

Title: Antibiotics for whooping cough (pertussis).

Journal: The Cochrane database of systematic reviews 20070718

Title: Nondestructive quantitative analysis of erythromycin ethylsuccinate powder drug via short-wave near-infrared spectroscopy combined with radial basis function neural networks.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070701

Title: Construction of universal quantitative models for determination of roxithromycin and erythromycin ethylsuccinate in tablets from different manufacturers using near infrared reflectance spectroscopy.

Journal: Journal of pharmaceutical and biomedical analysis 20060503

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Simultaneous determination of erythromycin ethylsuccinate and its metabolite erythromycin in human plasma using liquid chromatography-electrospray ionization mass spectrometry for clinical study.

Journal: Journal of pharmaceutical and biomedical analysis 20060224

Title: A validated spectrofluorometric assay for the determination of certain macrolide antibiotics in pharmaceutical formulations and spiked biological fluids.

Journal: Journal of AOAC International 20060101

Title: Antibiotics for whooping cough (pertussis).

Journal: The Cochrane database of systematic reviews 20050125

Title: Pharmacokinetics of erythromycin ethylsuccinate after intragastric administration to healthy foals.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20020101

Title: Open-Label, parallel-group, multicenter, randomized study of cefprozil versus erythromycin in children with group A streptococcal pharyngitis/tonsillitis.

Journal: Clinical therapeutics 20011101

Title: Synergistic anti-Pneumocystis carinii effects of erythromycin and sulfisoxazole.

Journal: Journal of acquired immune deficiency syndromes 19910101

Title: Prolonged cholestasis and disappearance of interlobular bile ducts following chlorpropamide and erythromycin ethylsuccinate. Case of drug interaction?

Journal: Liver 19881201

Title: Gustafsson A, et al. The association of erythromycin ethylsuccinate with acute colitis in horses in Sweden. Equine Vet J. 1997 Jul;29(4):314-8.

Title: Feng YC, et al. Construction of universal quantitative models for determination of roxithromycin and erythromycin ethylsuccinate in tablets from different manufacturers using near infrared reflectance spectroscopy. J Pharm Biomed Anal. 2006 May 3;41(2):373-84.

Title: Komuro I, et al. Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBPbeta. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12509-14.

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Tags:1264-62-6 Molecular Formula|1264-62-6 MDL|1264-62-6 SMILES|1264-62-6 Erythromycin, 2'-(ethyl butanedioate)