Title: Selective gene dependencies in MYCN-amplified neuroblastoma include the core transcriptional regulatory circuitry.
Journal: Nature genetics 20180901
Title: Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells.
Journal: The Journal of biological chemistry 20180216
Title: Inhibition of Bromodomain and Extraterminal Domain Family Proteins Ameliorates Experimental Renal Damage.
Journal: Journal of the American Society of Nephrology : JASN 20170201
Title: Bromodomain and Extraterminal Protein Inhibitor JQ1 Suppresses Thyroid Tumor Growth in a Mouse Model.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20170115
Title: The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.
Journal: Oncogene 20170105
Title: Design and characterization of bivalent BET inhibitors.
Journal: Nature chemical biology 20161201
Title: The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease.
Journal: Current Alzheimer research 20160901
Title: Antimyeloma activity of bromodomain inhibitors on the human myeloma cell line U266 by downregulation of MYCL.
Journal: Anti-cancer drugs 20160901
Title: BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members.
Journal: Molecular cancer therapeutics 20160901
Title: Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-β-dependent mechanisms.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20160802
Title: In Silico Analysis Guides Selection of BET Inhibitors for Triple-Negative Breast Cancer Treatment.
Journal: Molecular cancer therapeutics 20160801
Title: BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma.
Journal: Oncotarget 20160712
Title: Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells.
Journal: Molecular cancer therapeutics 20160601
Title: Nonselective inhibition of the epigenetic transcriptional regulator BET induces marked lymphoid and hematopoietic toxicity in mice.
Journal: Toxicology and applied pharmacology 20160601
Title: BET and BRAF inhibitors act synergistically against BRAF-mutant melanoma.
Journal: Cancer medicine 20160601
Title: Epigenetic reader BRD4 inhibition as a therapeutic strategy to suppress E2F2-cell cycle regulation circuit in liver cancer.
Journal: Oncotarget 20160531
Title: The Bromodomain Inhibitor JQ1 and the Histone Deacetylase Inhibitor Panobinostat Synergistically Reduce N-Myc Expression and Induce Anticancer Effects.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20160515
Title: The Bromodomain BET Inhibitor JQ1 Suppresses Tumor Angiogenesis in Models of Childhood Sarcoma.
Journal: Molecular cancer therapeutics 20160501
Title: BRD4 Regulates EZH2 Transcription through Upregulation of C-MYC and Represents a Novel Therapeutic Target in Bladder Cancer.
Journal: Molecular cancer therapeutics 20160501
Title: Keap1-Independent Regulation of Nrf2 Activity by Protein Acetylation and a BET Bromodomain Protein.
Journal: PLoS genetics 20160501
Title: Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1.
Journal: Oncotarget 20160426
Title: Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits BET Bromodomain Proteins.
Journal: Cancer research 20160415
Title: Inhibition of the acetyl lysine-binding pocket of bromodomain and extraterminal domain proteins interferes with adipogenesis.
Journal: Biochemical and biophysical research communications 20160415
Title: MYC regulates the antitumor immune response through CD47 and PD-L1.
Journal: Science (New York, N.Y.) 20160408
Title: MCM5 as a target of BET inhibitors in thyroid cancer cells.
Journal: Endocrine-related cancer 20160401
Title: Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas.
Journal: Cancer research 20160315
Title: The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models.
Journal: Oncogene 20160218
Title: Dual mTOR inhibitor MLN0128 suppresses Merkel cell carcinoma (MCC) xenograft tumor growth.
Journal: Oncotarget 20160209
Title: Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration.
Journal: Journal of hepatology 20160201
Title: CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer.
Journal: The Journal of clinical investigation 20160201
Title: Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer.
Journal: Nature 20160121
Title: Suppression of BRD4 inhibits human hepatocellular carcinoma by repressing MYC and enhancing BIM expression.
Journal: Oncotarget 20160119
Title: Inhibition of BRD4 suppresses tumor growth and enhances iodine uptake in thyroid cancer.
Journal: Biochemical and biophysical research communications 20160115
Title: Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.
Journal: Oncotarget 20160112
Title: Bromodomain and extra-terminal domain bromodomain inhibition prevents synovial inflammation via blocking IκB kinase-dependent NF-κB activation in rheumatoid fibroblast-like synoviocytes.
Journal: Rheumatology (Oxford, England) 20160101
Title: BET protein inhibitor JQ1 inhibits growth and modulates WNT signaling in mesenchymal stem cells.
Journal: Stem cell research & therapy 20160101
Title: BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1.
Journal: Theranostics 20160101
Title: BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell.
Journal: PloS one 20160101
Title: BET Bromodomain Suppression Inhibits VEGF-induced Angiogenesis and Vascular Permeability by Blocking VEGFR2-mediated Activation of PAK1 and eNOS.
Journal: Scientific reports 20160101
Title: BRD4 is a novel therapeutic target for liver fibrosis.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20151222
Title: Therapeutic targeting of BET protein BRD4 delays murine lupus.
Journal: International immunopharmacology 20151201
Title: Epigenetic Readers of Lysine Acetylation Regulate Cocaine-Induced Plasticity.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20151111
Title: The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition.
Journal: Oncotarget 20151027
Title: Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells.
Journal: Oncotarget 20151020
Title: BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells.
Journal: Oncotarget 20151020
Title: EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling.
Journal: Molecular cell 20151015
Title: Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression.
Journal: Molecular cancer therapeutics 20151001
Title: BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice.
Journal: Nature neuroscience 20151001
Title: Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
Journal: Nature medicine 20151001
Title: Complete hematologic response of early T-cell progenitor acute lymphoblastic leukemia to the γ-secretase inhibitor BMS-906024: genetic and epigenetic findings in an outlier case.
Journal: Cold Spring Harbor molecular case studies 20151001
Title: Inhibition of Super-Enhancer Activity in Autoinflammatory Site-Derived T Cells Reduces Disease-Associated Gene Expression.
Journal: Cell reports 20150929
Title: Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib.
Journal: Blood 20150924
Title: BET inhibitor resistance emerges from leukaemia stem cells.
Journal: Nature 20150924
Title: Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6.
Journal: Nucleic acids research 20150918
Title: Bromodomain and extraterminal inhibition blocks tumor progression and promotes differentiation in neuroblastoma.
Journal: Surgery 20150901
Title: Imiquimod-induced psoriasis-like skin inflammation is suppressed by BET bromodomain inhibitor in mice through RORC/IL-17A pathway modulation.
Journal: Pharmacological research 20150901
Title: BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses.
Journal: Chembiochem : a European journal of chemical biology 20150901
Title: Bromodomain-Containing Protein 4: The Epigenetic Origin of Pulmonary Arterial Hypertension.
Journal: Circulation research 20150828
Title: CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20150825
Title: Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition.
Journal: Oncotarget 20150814
Title: Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.
Journal: Human molecular genetics 20150715
Title: Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies.
Journal: Nucleic acids research 20150713
Title: BET inhibitor OTX015 targets BRD2 and BRD4 and decreases c-MYC in acute leukemia cells.
Journal: Oncotarget 20150710
Title: Synergistic induction of cell death in haematological malignancies by combined phosphoinositide-3-kinase and BET bromodomain inhibition.
Journal: British journal of haematology 20150701
Title: Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion.
Journal: Oncotarget 20150630
Title: BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia.
Journal: Molecular cell 20150618
Title: Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4.
Journal: Chemistry & biology 20150618
Title: A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies.
Journal: Oncogene 20150601
Title: Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma.
Journal: International journal of cancer 20150501
Title: BET bromodomain inhibition suppresses graft-versus-host disease after allogeneic bone marrow transplantation in mice.
Journal: Blood 20150423
Title: Deacetylase inhibitors repress STAT5-mediated transcription by interfering with bromodomain and extra-terminal (BET) protein function.
Journal: Nucleic acids research 20150420
Title: Nanog requires BRD4 to maintain murine embryonic stem cell pluripotency and is suppressed by bromodomain inhibitor JQ1 together with Lefty1.
Journal: Stem cells and development 20150401
Title: Inhibition of BET proteins impairs estrogen-mediated growth and transcription in breast cancers by pausing RNA polymerase advancement.
Journal: Breast cancer research and treatment 20150401
Title: Inhibiting STAT5 by the BET bromodomain inhibitor JQ1 disrupts human dendritic cell maturation.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20150401
Title: [Mechanism of Notch1 Pathway in SUP-B15 Cell Apoptosis Induced by JQ1].
Journal: Zhongguo shi yan xue ye xue za zhi 20150401
Title: JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer.
Journal: Oncotarget 20150330
Title: The MZF1/c-MYC axis mediates lung adenocarcinoma progression caused by wild-type lkb1 loss.
Journal: Oncogene 20150326
Title: BRAD4 plays a critical role in germinal center response by regulating Bcl-6 and NF-κB activation.
Journal: Cellular immunology 20150301
Title: Epstein-Barr virus oncoprotein super-enhancers control B cell growth.
Journal: Cell host & microbe 20150211
Title: Bromodomain inhibition by JQ1 suppresses lipopolysaccharide-stimulated interleukin-6 secretion in multiple myeloma cells.
Journal: Cytokine 20150201
Title: Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers.
Journal: Oncotarget 20150201
Title: An in-tumor genetic screen reveals that the BET bromodomain protein, BRD4, is a potential therapeutic target in ovarian carcinoma.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20150106
Title: Inhibition of bromodomain proteins for the treatment of human diffuse large B-cell lymphoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20150101
Title: GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1.
Journal: Scientific reports 20150101
Title: RNA sequencing reveals distinct mechanisms underlying BET inhibitor JQ1-mediated modulation of the LPS-induced activation of BV-2 microglial cells.
Journal: Journal of neuroinflammation 20150101
Title: BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cells.
Journal: Scientific reports 20150101
Title: Direct and indirect targeting of MYC to treat acute myeloid leukemia.
Journal: Cancer chemotherapy and pharmacology 20150101
Title: Perturbation biology nominates upstream-downstream drug combinations in RAF inhibitor resistant melanoma cells.
Journal: eLife 20150101
Title: Dual transcriptome sequencing reveals resistance of TLR4 ligand-activated bone marrow-derived macrophages to inflammation mediated by the BET inhibitor JQ1.
Journal: Scientific reports 20150101
Title: Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth.
Journal: Drug design, development and therapy 20150101
Title: BET protein inhibitor JQ1 attenuates Myc-amplified MCC tumor growth in vivo.
Journal: Cancer research 20141201
Title: BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones.
Journal: Nature structural & molecular biology 20141201
Title: Chemical biology. A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes.
Journal: Science (New York, N.Y.) 20141031
Title: NF-κB directs dynamic super enhancer formation in inflammation and atherogenesis.
Journal: Molecular cell 20141023
Title: PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies.
Journal: Nature 20141009
Title: BET protein antagonist JQ1 is synergistically lethal with FLT3 tyrosine kinase inhibitor (TKI) and overcomes resistance to FLT3-TKI in AML cells expressing FLT-ITD.
Journal: Molecular cancer therapeutics 20141001
Title: Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20140805
Title: 'Minimalist' cyclopropene-containing photo-cross-linkers suitable for live-cell imaging and affinity-based protein labeling.
Journal: Journal of the American Chemical Society 20140716
Title: Inducible STAT3 NH2 terminal mono-ubiquitination promotes BRD4 complex formation to regulate apoptosis.
Journal: Cellular signalling 20140701
Title: BET Inhibitor JQ1 Blocks Inflammation and Bone Destruction.
Journal: Journal of dental research 20140701
Title: An epigenomic approach to therapy for tamoxifen-resistant breast cancer.
Journal: Cell research 20140701
Title: Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition.
Journal: Nature medicine 20140701
Title: Activation of SOX2 expression by BRD4-NUT oncogenic fusion drives neoplastic transformation in NUT midline carcinoma.
Journal: Cancer research 20140615
Title: Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer.
Journal: Nature 20140612
Title: Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1.
Journal: Oncotarget 20140601
Title: Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors.
Journal: Oncogene 20140529
Title: Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20140515
Title: MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia.
Journal: Cancer cell 20140512
Title: Brd4 maintains constitutively active NF-κB in cancer cells by binding to acetylated RelA.
Journal: Oncogene 20140501
Title: Highly active combination of BRD4 antagonist and histone deacetylase inhibitor against human acute myelogenous leukemia cells.
Journal: Molecular cancer therapeutics 20140501
Title: Targeting STAT5 in hematologic malignancies through inhibition of the bromodomain and extra-terminal (BET) bromodomain protein BRD2.
Journal: Molecular cancer therapeutics 20140501
Title: Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma.
Journal: Oncotarget 20140501
Title: Therapeutic targeting of c-Myc in T-cell acute lymphoblastic leukemia, T-ALL.
Journal: Oncotarget 20140501
Title: The bromodomain protein BRD4 regulates the KEAP1/NRF2-dependent oxidative stress response.
Journal: Cell death & disease 20140401
Title: Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.
Journal: The Journal of biological chemistry 20140328
Title: Selective inhibition of BET bromodomain epigenetic signalling interferes with the bone-associated tumour vicious cycle.
Journal: Nature communications 20140319
Title: The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis.
Journal: Journal of leukocyte biology 20140301
Title: BET bromodomain inhibition of MYC-amplified medulloblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20140215
Title: c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.
Journal: Blood 20140213
Title: Regulation of MYC expression and differential JQ1 sensitivity in cancer cells.
Journal: PloS one 20140101
Title: Brd4 is essential for IL-1β-induced inflammation in human airway epithelial cells.
Journal: PloS one 20140101
Title: The histone deacetylase Hdac1 regulates inflammatory signalling in intestinal epithelial cells.
Journal: Journal of inflammation (London, England) 20140101
Title: Discovery and characterization of super-enhancer-associated dependencies in diffuse large B cell lymphoma.
Journal: Cancer cell 20131209
Title: Disruption of the MYC-miRNA-EZH2 loop to suppress aggressive B-cell lymphoma survival and clonogenicity.
Journal: Leukemia 20131201
Title: BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1.
Journal: Cancer medicine 20131201
Title: Efficacy of BET bromodomain inhibition in Kras-mutant non-small cell lung cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20131115
Title: BET bromodomain protein inhibition is a therapeutic option for medulloblastoma.
Journal: Oncotarget 20131101
Title: BET acetyl-lysine binding proteins control pathological cardiac hypertrophy.
Journal: Journal of molecular and cellular cardiology 20131001
Title: Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors.
Journal: ACS medicinal chemistry letters 20130912
Title: Assessment of Brd4 inhibition in idiopathic pulmonary fibrosis lung fibroblasts and in vivo models of lung fibrosis.
Journal: The American journal of pathology 20130801
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Identification of a novel BET bromodomain inhibitor-sensitive, gene regulatory circuit that controls Rituximab response and tumour growth in aggressive lymphoid cancers.
Journal: EMBO molecular medicine 20130801
Title: BET inhibition as a single or combined therapeutic approach in primary paediatric B-precursor acute lymphoblastic leukaemia.
Journal: Blood cancer journal 20130701
Title: BRD4 coordinates recruitment of pause release factor P-TEFb and the pausing complex NELF/DSIF to regulate transcription elongation of interferon-stimulated genes.
Journal: Molecular and cellular biology 20130601
Title: The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy.
Journal: Genes & development 20130601
Title: Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands.
Journal: Journal of medicinal chemistry 20130425
Title: Selective inhibition of tumor oncogenes by disruption of super-enhancers.
Journal: Cell 20130411
Title: Inhibition of BET bromodomain targets genetically diverse glioblastoma.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20130401
Title: BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20130401
Title: Targeting MYCN in neuroblastoma by BET bromodomain inhibition.
Journal: Cancer discovery 20130301
Title: Androgen receptor promotes ligand-independent prostate cancer progression through c-Myc upregulation.
Journal: PloS one 20130101
Title: Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells.
Journal: The Journal of biological chemistry 20121214
Title: BET bromodomain inhibition as a novel strategy for reactivation of HIV-1.
Journal: Journal of leukocyte biology 20121201
Title: Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20121120
Title: Reactivation of latent HIV-1 by inhibition of BRD4.
Journal: Cell reports 20121025
Title: Bromodomain and extra-terminal (BET) bromodomain inhibition activate transcription via transient release of positive transcription elongation factor b (P-TEFb) from 7SK small nuclear ribonucleoprotein.
Journal: The Journal of biological chemistry 20121019
Title: BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia.
Journal: Blood 20121004
Title: Small-molecule inhibition of BRDT for male contraception.
Journal: Cell 20120817
Title: Cancer research: Open ambition.
Journal: Nature 20120809
Title: Benzodiazepines and benzotriazepines as protein interaction inhibitors targeting bromodomains of the BET family.
Journal: Bioorganic & medicinal chemistry 20120315
Title: Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides.
Journal: Journal of medicinal chemistry 20120126
Title: Targeting MYC dependence in cancer by inhibiting BET bromodomains.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20111004
Title: BET bromodomain inhibition as a therapeutic strategy to target c-Myc.
Journal: Cell 20110916
Title: RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.
Journal: Nature 20110803
Title: Selective inhibition of BET bromodomains.
Journal: Nature 20101223
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