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Home Pyridines 1270084-92-8
1270084-92-8
Catalog No.:AA01KKA2

1270084-92-8 | 3-Phenyl-4-propyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol

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Purity
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Price(USD)
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50mg
95%
in stock  
$381.00   $267.00
- +
100mg
95%
in stock  
$519.00   $363.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01KKA2
Chemical Name:
3-Phenyl-4-propyl-1-(pyridin-2-yl)-1H-pyrazol-5-ol
CAS Number:
1270084-92-8
Molecular Formula:
C17H17N3O
Molecular Weight:
279.3364
SMILES:
CCCc1c([nH]n(c1=O)c1ccccn1)c1ccccc1
Properties

Downstream Synthesis Route

[1]Bae,YunSoo;Choi,YoonMi;Kamma,KoteswaraR.;Kim,Chong-Hyeak;Lee,Kee-In;Sadu,VenkataS.[JournalofMolecularStructure,2020,vol.1215]

[2]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-EP2682392,2014,A2Locationinpatent:Paragraph0077-0080

[3]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-US2014/128418,2014,A1Locationinpatent:Paragraph0189;0190;0191;0192

[4]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-EP2889032,2015,A1Locationinpatent:Paragraph0038;0039;0040;0041

[5]CurrentPatentAssignee:APTABIOTHERAPEUTICSINC-WO2019/88444,2019,A1Locationinpatent:Paragraph89-92

[6]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-US2012/220550,2012,A1Locationinpatent:Page/Pagecolumn20

[7]CurrentPatentAssignee:APTABIOTHERAPEUTICSINC-KR101856444,2018,B1Locationinpatent:Paragraph0093-0094;0099-0100

258841-42-8    1270084-92-8   
1-(pyridin-2-yl)-3-phenyl-4-propyl-1H-5-(isopropyloxycarbonyloxymethyloxy)pyrazole 

[1]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-EP2682392,2014,A2Locationinpatent:Paragraph0086-0089

[2]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-US2014/128418,2014,A1Locationinpatent:Paragraph0203;0204;0205;0206

1270084-92-8   
1-(pyridin-2-yl)-3-phenyl-4-propyl-1H-pyrazol-5-olhydrogenchloride 

[1]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-EP2682392,2014,A2Locationinpatent:Paragraph0085

[2]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-US2014/88152,2014,A1Locationinpatent:Paragraph0537-0540

[3]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-US2014/128418,2014,A1Locationinpatent:Paragraph0200;0201;0202

[4]CurrentPatentAssignee:EWHAWOMANSUNIVERSITY-EP2889032,2015,A1Locationinpatent:Paragraph0042;0043;0044

[5]CurrentPatentAssignee:APTABIOTHERAPEUTICSINC-KR101856444,2018,B1Locationinpatent:Paragraph0096-0097;0101-0102

[6]CurrentPatentAssignee:APTABIOTHERAPEUTICSINC-WO2019/88444,2019,A1Locationinpatent:Paragraph94-97

258841-42-8    1270084-92-8   
1-(pyridin-2-yl)-3-phenyl-4-propyl-1H-5-(isopropyloxycarbonyloxymethyloxy)pyrazole 
 
1-isopropyloxycarbonyloxymethyl-2-(2-pyridinyl)-4-propyl-5-phenyl-1,2-dihydro-3H-pyrazol-3-one 

[1]Bae,YunSoo;Choi,YoonMi;Kamma,KoteswaraR.;Kim,Chong-Hyeak;Lee,Kee-In;Sadu,VenkataS.[JournalofMolecularStructure,2020,vol.1215]

Literature

Title: Kwon G, et al. A novel pan-Nox inhibitor, APX-115, protects kidney injury in streptozotocin-induced diabetic mice: possible role of peroxisomal and mitochondrial biogenesis. Oncotarget. 2017 Jun 16;8(43):74217-74232.

Title: Cha JJ, et al. APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury. Lab Invest. 2017 Apr;97(4):419-431.

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