Catalog No.:AA009WMF

1279034-84-2 | 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8h)-one hydrochloride

Name: Name:6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8h)-one hydrochloride
Brand: AABLOCKS
SKU: AA009WMF
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

Availability

Price(USD)

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1mg

98%

2 weeks

$100.00 $70.00

- +

2mg

98%

2 weeks

$135.00 $94.00

- +

5mg

98%

2 weeks

$231.00 $162.00

- +

10mg

98%

2 weeks

$360.00 $252.00

- +

25mg

98%

2 weeks

$565.00 $396.00

- +

50mg

98%

2 weeks

$1,030.00 $721.00

- +

100mg

98%

2 weeks

$1,491.00 $1,044.00

- +

Technical Information
Properties
Literature
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Technical Information
Properties
Literature

Technical Information

Catalog Number:

AA009WMF

Chemical Name:

6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8h)-one hydrochloride

CAS Number:

1279034-84-2

Molecular Formula:

C25H31ClN8OS

Molecular Weight:

527.0846

MDL Number:

MFCD22420809

SMILES:

CC1=NC2=C(C(=N1)NC3=NNC4=C3CN(C4(C)C)C(=O)NC(CN(C)C)C5=CC=CC=C5)SC=C2.Cl

Properties

Literature

Title: Murray, Brion W., et al. Small-molecule p21-activated kinase inhibitor PF3758309 is a potent inhibitor of oncogenic signaling and tumor growth. Proceedings of the National Academy of Sciences of the United States of America (2010), 107(20), 9446-9451, S94.

Title: Zhao ZS, et al. Do PAKs make good drug targets? F1000 Biol Rep. 2010 Sep 23;2:70.

Title: Ryu BJ, et al. PF-3758309, p21-activated kinase 4 inhibitor, suppresses migration and invasion of A549 human lung cancer cells via regulation of CREB, NF-κB, and β-catenin signalings. Mol Cell Biochem. 2014 Apr;389(1-2):69-77.

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