Title: The BET inhibitor JQ1 selectively impairs tumour response to hypoxia and downregulates CA9 and angiogenesis in triple negative breast cancer.
Journal: Oncogene 20170105
Title: Antimyeloma activity of bromodomain inhibitors on the human myeloma cell line U266 by downregulation of MYCL.
Journal: Anti-cancer drugs 20160901
Title: Bromodomain and extraterminal (BET) proteins regulate biliary-driven liver regeneration.
Journal: Journal of hepatology 20160201
Title: BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1.
Journal: Theranostics 20160101
Title: BRD4 is a novel therapeutic target for liver fibrosis.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20151222
Title: Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib.
Journal: Blood 20150924
Title: BET bromodomain inhibition suppresses graft-versus-host disease after allogeneic bone marrow transplantation in mice.
Journal: Blood 20150423
Title: GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1.
Journal: Scientific reports 20150101
Title: Blockade of oncogenic IκB kinase activity in diffuse large B-cell lymphoma by bromodomain and extraterminal domain protein inhibitors.
Journal: Proceedings of the National Academy of Sciences of the United States of America 20140805
Title: Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1.
Journal: Oncotarget 20140601
Title: Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors.
Journal: Oncogene 20140529
Title: Potent antimyeloma activity of the novel bromodomain inhibitors I-BET151 and I-BET762.
Journal: Blood 20140130
Title: Discovery, Design, and Optimization of Isoxazole Azepine BET Inhibitors.
Journal: ACS medicinal chemistry letters 20130912
Title: Optimization of 3,5-dimethylisoxazole derivatives as potent bromodomain ligands.
Journal: Journal of medicinal chemistry 20130425
Title: From ApoA1 upregulation to BET family bromodomain inhibition: discovery of I-BET151.
Journal: Bioorganic & medicinal chemistry letters 20120415
Title: Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides.
Journal: Journal of medicinal chemistry 20120126
Title: Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia.
Journal: Nature 20111002
