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13074-60-7,MFCD29034734
Catalog No.:AA000UTD

13074-60-7 | 2-Butenedioic acid, 2-ethyl-, (2Z)-

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  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA000UTD
Chemical Name:
2-Butenedioic acid, 2-ethyl-, (2Z)-
CAS Number:
13074-60-7
Molecular Formula:
C6H8O4
Molecular Weight:
144.1253
MDL Number:
MFCD29034734
SMILES:
CC/C(=C/C(=O)O)/C(=O)O
Properties
Computed Properties
 
Complexity:
180  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
Undefined Bond Stereocenter Count:
1  
XLogP3:
0.4  

Literature

Title: Characterization of a thermostable methylaspartate ammonia lyase from Carboxydothermus hydrogenoformans.

Journal: Applied microbiology and biotechnology 20120401

Title: Pharmacokinetics of anti-psoriatic fumaric acid esters in psoriasis patients.

Journal: Archives of dermatological research 20100901

Title: Fumaric acid dialkyl esters deprive cultured rat oligodendroglial cells of glutathione and upregulate the expression of heme oxygenase 1.

Journal: Neuroscience letters 20100507

Title: Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response.

Journal: PLoS biology 20100301

Title: Cut and paste: a novel method of re-attaching rectus muscles with cyanoacrylate during recessions in strabismus.

Journal: Indian journal of ophthalmology 20100101

Title: Fumaric Acid and its esters: an emerging treatment for multiple sclerosis.

Journal: Current neuropharmacology 20090301

Title: Fumaric acid and its derivatives in the treatment of psoriasis vulgaris: our experience in forty-one patients.

Journal: Acta dermatovenerologica Croatica : ADC 20090101

Title: Fumaric acid esters.

Journal: Clinics in dermatology 20080101

Title: Dimethylfumarate induces immunosuppression via glutathione depletion and subsequent induction of heme oxygenase 1.

Journal: The Journal of investigative dermatology 20070401

Title: Use of fumaric acid esters in psoriasis.

Journal: Indian journal of dermatology, venereology and leprology 20070101

Title: BG 12: BG 00012, BG 12/Oral Fumarate, FAG-201, second-generation fumarate derivative--Fumapharm/Biogen Idec.

Journal: Drugs in R&D 20050101

Title: Pharmacokinetics of oral fumarates in healthy subjects.

Journal: British journal of clinical pharmacology 20041001

Title: In vitro pharmacokinetics of anti-psoriatic fumaric acid esters.

Journal: BMC pharmacology 20040101

Title: Presystemic metabolism and intestinal absorption of antipsoriatic fumaric acid esters.

Journal: Biopharmaceutics & drug disposition 20030901

Title: Plausible molecular mechanism for activation by fumarate and electron transfer of the dopamine beta-mono-oxygenase reaction.

Journal: The Biochemical journal 20021001

Title: Treatment of disseminated granuloma annulare with fumaric acid esters.

Journal: BMC dermatology 20020101

Title: Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters.

Journal: BMC dermatology 20020101

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Tags:13074-60-7 Molecular Formula|13074-60-7 MDL|13074-60-7 SMILES|13074-60-7 2-Butenedioic acid, 2-ethyl-, (2Z)-