Home Other Building Blocks 1315451-25-2
1315451-25-2,MFCD22123244
Catalog No.:AA00A1DH

1315451-25-2 | Nav1.7 blocker 24

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
99%
in stock  
$333.00   $233.00
- +
50mg
99%
in stock  
$1,158.00   $810.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00A1DH
Chemical Name:
Nav1.7 blocker 24
CAS Number:
1315451-25-2
Molecular Formula:
C20H16Cl2F3N3O3
Molecular Weight:
474.2605
MDL Number:
MFCD22123244
SMILES:
CC1=C(C(=NO1)C2=C(C=CC=C2Cl)Cl)CC(=O)NCC3=CN=C(C=C3)OCC(F)(F)F
Properties
Computed Properties
 
Complexity:
592  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
4.7  

Literature

Title: Novel bioactivation mechanism of reactive metabolite formation from phenyl methyl-isoxazoles.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20121101

Title: Activation of nociceptin/orphanin FQ peptide receptors disrupts visual but not auditory sensorimotor gating in BALB/cByJ mice: comparison to dopamine receptor agonists.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120101

Title: Phenyl isoxazole voltage-gated sodium channel blockers: structure and activity relationship.

Journal: Bioorganic & medicinal chemistry letters 20110701

Title: Pharmacological characterization of the nociceptin/orphanin FQ receptor non peptide antagonist Compound 24.

Journal: European journal of pharmacology 20090701

Title: Activation of phospholipases A2 and D of a human neuroblastoma cell line (LA-N-2) by N-dodecyl-L-lysine amide (compound 24), a putative G protein activator: characteristics of inhibition by (-)-nicotine.

Journal: Neurochemical research 20021201

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 1315451-25-2
Tags:1315451-25-2 Molecular Formula|1315451-25-2 MDL|1315451-25-2 SMILES|1315451-25-2 Nav1.7 blocker 24