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1330286-50-4,MFCD08274465
Catalog No.:AA009WOV

1330286-50-4 | (3S)-Trichloromethyl-cis-tetrahydropyrrolo[1,2-c]oxazol-1-one

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
≥ 97% (NMR)
in stock  
$162.00   $114.00
- +
1g
≥ 97% (NMR)
in stock  
$310.00   $217.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA009WOV
Chemical Name:
(3S)-Trichloromethyl-cis-tetrahydropyrrolo[1,2-c]oxazol-1-one
CAS Number:
1330286-50-4
Molecular Formula:
C7H8Cl3NO2
Molecular Weight:
244.5029
MDL Number:
MFCD08274465
SMILES:
O=C1O[C@H](N2[C@@H]1CCC2)C(Cl)(Cl)Cl
Properties
Computed Properties
 
Complexity:
240  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
XLogP3:
2.5  

Downstream Synthesis Route

[1]Su,Bo;Cai,Chunlong;Wang,Qingmin[JournalofOrganicChemistry,2012,vol.77,#18,p.7981-7987]

[2]CurrentPatentAssignee:APTINYXINC.-WO2017/201283,2017,A1Locationinpatent:Page/Pagecolumn34

[3]CurrentPatentAssignee:ABBVIEINC-WO2020/263847,2020,A1Locationinpatent:Paragraph00154-00155

[4]CurrentPatentAssignee:ABBVIEINC-WO2020/263848,2020,A1Locationinpatent:Paragraph00293-00294

[5]CurrentPatentAssignee:APTINYXINC.-WO2017/201285,2017,A1Locationinpatent:Page/Pagecolumn33

[6]KAsperowicz-Frankowska,Katarzyna;Kolesińska,Beata;Gzik,Anna;Jastrzabek,Konrad;Kamiński,ZbigniewJ.[Actapoloniaepharmaceutica,2018,vol.75,#4,p.921-927]

[7]CurrentPatentAssignee:ASTRAZENECAPLC-WO2019/159120,2019,A1Locationinpatent:Page/Pagecolumn35

[8]CurrentPatentAssignee:AMGENINC-WO2014/152127,2014,A1Locationinpatent:Paragraph00304;00305

[1]Wang,Hexiang;Ren,Bo;Liu,Ye;Jiang,Beibei;Guo,Yin;Wei,Min;Luo,Lusong;Kuang,Xianzhao;Qiu,Ming;Lv,Lei;Xu,Hong;Qi,Ruipeng;Yan,Huibin;Xu,Dexu;Wang,Zhiwei;Huo,Chang-Xin;Zhu,Yutong;Zhao,Yuan;Wu,Yiyuan;Qin,Zhen;Su,Dan;Tang,Tristin;Wang,Fan;Sun,Xuebing;Feng,Yingcai;Peng,Hao;Wang,Xing;Gao,Yajuan;Liu,Yong;Gong,Wenfeng;Yu,Fenglong;Liu,Xuesong;Wang,Lai;Zhou,Changyou[JournalofMedicinalChemistry,2020,vol.63,#24,p.15541-15563]

Literature
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SDS
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Tags:1330286-50-4 Molecular Formula|1330286-50-4 MDL|1330286-50-4 SMILES|1330286-50-4 (3S)-Trichloromethyl-cis-tetrahydropyrrolo[1,2-c]oxazol-1-one