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[2]Keenan,RichardM.;Weinstock,Joseph;Finkelstein,JosephA.;Franz,RobertG.;Gaitanopoulos,DimitriE.;etal.[JournalofMedicinalChemistry,1993,vol.36,#13,p.1880-1892]
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[1]SyntheticCommunications,1993,vol.23,p.3231-3248
[2]SyntheticCommunications,1993,vol.23,p.3231-3248
[1]Wittenberger;Tasker;Sorensen;Donner[SyntheticCommunications,1993,vol.23,#22,p.3231-3248]
[2]Weinstock,Joseph;Keenan,RichardM.;Samanen,James;Hempel,Judith;Finkelstein,JosephA.;etal.[JournalofMedicinalChemistry,1991,vol.34,#4,p.1514-1517]
[3]Weinstock,Joseph;Keenan,RichardM.;Samanen,James;Hempel,Judith;Finkelstein,JosephA.;etal.[JournalofMedicinalChemistry,1991,vol.34,#4,p.1514-1517]
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[2]CurrentPatentAssignee:HETERODRUGSLIMITED-WO2008/78330,2008,A1Locationinpatent:Page/Pagecolumn8-9
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Title: Determination of eprosartan mesylate and hydrochlorothiazide in tablets by derivative spectrophotometric and high-performance liquid chromatographic methods.
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Title: Antihypertensive effects and safety of eprosartan: a meta-analysis of randomized controlled trials.
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Title: Blood pressure responses to hypertension treatment and trends in cognitive function in patients with initially difficult-to-treat hypertension: a retrospective subgroup analysis of the Observational Study on Cognitive Function and SBP Reduction (OSCAR) study.
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Title: [The use of melatonin for correction of sleep disturbances in assembly-line shift workers with arterial hypertension].
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Title: Effect of eprosartan-based therapy on systolic blood pressure and total cardiovascular risk in a large international population: preliminary report of the observational POWER study.
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Title: Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
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Title: CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.
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Title: The effect of eprosartan on reflex sympathetic activation in sodium restricted patients with essential hypertension.
Journal: Journal of the American Society of Hypertension : JASH 20110101
Title: Liquid chromatographic method for the simultaneous determination of eprosartan and hydrochlorothiazide in tablets and human plasma.
Journal: Journal of AOAC International 20110101
Title: Eprosartan-based hypertension therapy, systolic arterial blood pressure and cognitive function: analysis of Middle East data from the OSCAR study.
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Title: Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
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Title: Advanced glycation end-products, anti-hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction.
Journal: European journal of heart failure 20100401
Title: Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters.
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Title: Characterization of a novel impurity in bulk drug eprosartan by ESI/MS(n) and NMR.
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Title: Effects of eprosartan on diastolic function and neurohormones in patients with hypertension and diastolic dysfunction.
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Title: Development and validation of a high-performance liquid chromatographic method for determination of eprosartan in bulk drug and tablets.
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Title: Comparative effects of telmisartan and eprosartan on insulin sensitivity in the treatment of overweight hypertensive patients.
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Title: Cost-utility analysis of eprosartan compared to enalapril in primary prevention and nitrendipine in secondary prevention in Europe--the HEALTH model.
Journal: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20090901
Title: Effect of the multitargeted receptor tyrosine kinase inhibitor, ABT-869 [N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea], on blood pressure in conscious rats and mice: reversal with antihypertensive agents and effect on tumor growth inhibition.
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Title: Hemodynamic and cardiac effects of chronic eprosartan and moxonidine therapy in stroke-prone spontaneously hypertensive rats.
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Title: Angiotensin receptor blockers and secondary stroke prevention: the MOSES study.
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Title: Superoxide dismutase and catalase anti-oxidant activity in leucocyte lysates from hypertensive patients: effects of eprosartan treatment.
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Title: Costs of eprosartan versus diuretics for treatment of hypertension in a geriatric population: an observational, open-label, multicentre study.
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Title: [The use of melaxen in combined therapy of arterial hypertension in subjects occupied in assembly line production].
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Title: Eprosartan: a review of its use in hypertension.
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Journal: Cardiovascular & hematological agents in medicinal chemistry 20081001
Title: Effects of hypertension therapy based on eprosartan on systolic arterial blood pressure and cognitive function: primary results of the Observational Study on Cognitive function And Systolic Blood Pressure Reduction open-label study.
Journal: Journal of hypertension 20080801
Title: Effects of eprosartan on mitochondrial membrane potential and H2O2 levels in leucocytes in hypertension.
Journal: Journal of human hypertension 20080701
Title: Eprosartan modulates the reflex activation of the sympathetic nervous system in sodium restricted healthy humans.
Journal: British journal of clinical pharmacology 20080601
Title: Spectral and polarographic determination of eprosartan. Kinetic studies of the oxidation of eprosartan using a platinum electrode.
Journal: Die Pharmazie 20080601
Title: Effect of telmisartan on nitric oxide--asymmetrical dimethylarginine system: role of angiotensin II type 1 receptor gamma and peroxisome proliferator activated receptor gamma signaling during endothelial aging.
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Title: Separation and quantitation of several angiotensin II receptor antagonist drugs in human urine by a SPE-HPLC-DAD method.
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Title: Selenosartans: novel selenophene analogues of milfasartan and eprosartan.
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Title: Effectiveness of eprosartan in diabetic hypertensive patients.
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Title: Comparison of monotherapy versus combination antihypertensive therapy in elderly patients with essential hypertension.
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Journal: Kardiologiia 20080101
Title: [Effect of eprosartan on thrombocytes aggregative capacity in patients with arterial hypertension and metabolic syndrome].
Journal: Klinicheskaia meditsina 20080101
Title: Eprosartan in the primary prevention of cardiac allograft vascular disease: a double-blind prospectively randomized study using intravascular ultrasound.
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Title: Unique dual mechanism of action of eprosartan: effects on systolic blood pressure, pulse pressure, risk of stroke and cognitive decline.
Journal: Expert review of cardiovascular therapy 20071101
Title: Introduction: The pharmacological profile of eprosartan--implications for cerebrovascular and cardiovascular risk reduction.
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Title: Angiotensin blockade with eprosartan: vascular and functional implications.
Journal: Current medical research and opinion 20071101
Title: Observational Study on Cognitive function And systolic blood pressure Reduction (OSCAR): preliminary analysis of 6-month data from > 10,000 patients and review of the literature.
Journal: Current medical research and opinion 20071101
Title: Risk reduction by preventing stroke: need for blockade of angiotensin II and catecholamines?
Journal: Current medical research and opinion 20071101
Title: Pharmacokinetics and urinary excretion of eprosartan in Chinese healthy volunteers of different gender.
Journal: Die Pharmazie 20071001
Title: An update on non-peptide angiotensin receptor antagonists and related RAAS modulators.
Journal: Life sciences 20070802
Title: Effects of different AT1-receptor antagonists in the therapy of severe heart failure pretreated with ACE inhibitors.
Journal: Acta cardiologica 20070801
Title: Changes in fibrinolytic activity after angiotensin II receptor blockade in therapy-resistant hypertensive patients.
Journal: Journal of thrombosis and haemostasis : JTH 20070701
Title: Determination of eprosartan in human plasma and urine by LC/MS/MS.
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Title: [Role of the renin-angiotensin system on the sympathetic response induced by the cold pressor test in humans].
Journal: Investigacion clinica 20070601
Title: Small artery structure adapts to vasodilatation rather than to blood pressure during antihypertensive treatment.
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Title: Rationale, design and methods of the OSCAR study: observational study on cognitive function and systolic blood pressure reduction in hypertensive patients.
Journal: Fundamental & clinical pharmacology 20070401
Title: Effect of AT(1) angiotensin II receptor antagonists on the sympathetic response to a cold pressor test in healthy volunteers.
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Title: Eprosartan in secondary prevention of stroke: the economic evidence.
Journal: Cardiovascular journal of Africa 20070101
Title: [The effectiveness of eprosartan in patients with chronic glomerulonephritis].
Journal: Klinicheskaia meditsina 20070101
Title: Effects of eprosartan on serum metabolic parameters in patients with essential hypertension.
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Title: [Stress-associated hypertension in the work place: results of the STARLET project].
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Title: [Not all antihypertensive agents protect equally well].
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Title: Validation of a solid phase extraction-high performance liquid chromatographic method for the determination of eprosartan in human plasma.
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Title: Effect of eprosartan on the sympathetic response to cold pressor test in healthy volunteers.
Journal: Autonomic neuroscience : basic & clinical 20060630
Title: Does the MOSES study provide sufficient evidence for Eprosartan against Nitrendipine?
Journal: Stroke 20060601
Title: Effect of angiotensin II receptor blockade on autonomic nervous system function in patients with essential hypertension.
Journal: American journal of physiology. Heart and circulatory physiology 20060401
Title: Effects of eprosartan on target organ protection.
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Title: Morbidity and mortality after stroke--eprosartan compared with nitrendipine for secondary prevention: principal results of a prospective randomized controlled study (MOSES).
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Title: MOSES raises questions.
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Title: Atenolol and eprosartan: differential effects on central blood pressure and aortic pulse wave velocity.
Journal: American journal of hypertension 20060201
Title: Effects of antihypertensive treatment with angiotensin II receptor blockers on lipid profile: an open multi-drug comparison trial.
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Title: [An AT-II blocker in patients with type II diabetes and arterial hypertension].
Journal: Klinicheskaia meditsina 20060101
Title: Preventing cerebrovascular and cardiovascular events after stroke: eprosartan or nitrendipine?
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Journal: Kardiologiia 20060101
Title: Molecular characterization of new selective peroxisome proliferator-activated receptor gamma modulators with angiotensin receptor blocking activity.
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Journal: American journal of physiology. Heart and circulatory physiology 20051001
Title: Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy?
Journal: Journal of hypertension 20051001
Title: Haemodynamic effects of eprosartan and valsartan in hypertensive patients during isometric and mental stress.
Journal: Journal of hypertension 20051001
Title: Analysis of recent papers in hypertension. An angiotensin receptor blocker is more effective than a calcium channel blocker in secondary stroke prevention.
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Title: Adrenal angiotensin: origin and site of generation.
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Title: Pharmacophore, drug metabolism, and pharmacokinetics models on non-peptide AT1, AT2, and AT1/AT2 angiotensin II receptor antagonists.
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Title: Morbidity and Mortality After Stroke, Eprosartan Compared with Nitrendipine for Secondary Prevention: principal results of a prospective randomized controlled study (MOSES).
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Title: [Effect of a combination of teveten and prestarium in patients with chronic heart failure].
Journal: Georgian medical news 20050601
Title: Effectiveness and safety of eprosartan on pulse pressure for the treatment of hypertensive patients.
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Title: Effect of eprosartan on catecholamines and peripheral haemodynamics in subjects with insulin-induced hypoglycaemia.
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Title: Losartan increases bradykinin levels in hypertensive humans.
Journal: Circulation 20050125
Title: Eprosartan (Teveten) offers new opportunities to prevent a second stroke.
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Title: [Cerebral hemodynamics and endothelium function in patients with cerebrovascular pathology treated by teveten].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20050101
Title: Angiotensin receptor blockade and arterial compliance in chronic kidney disease: a pilot study.
Journal: American journal of nephrology 20050101
Title: Eprosartan: a review of its use in the management of hypertension.
Journal: Drugs 20050101
Title: Plasma vascular endothelial growth factor, angiopoietin-2, and soluble angiopoietin receptor tie-2 in diabetic retinopathy: effects of laser photocoagulation and angiotensin receptor blockade.
Journal: The British journal of ophthalmology 20041201
Title: Effect of eprosartan on pulse pressure and blood pressure components in patients with isolated systolic hypertension.
Journal: Blood pressure. Supplement 20041201
Title: Moxonidine normalizes sympathetic hyperactivity in patients with eprosartan-treated chronic renal failure.
Journal: Journal of the American Society of Nephrology : JASN 20041101
Title: New tools, old challenges: the emerging role of angiotensin receptor blockers in the treatment of the systolic hypertension epidemic.
Journal: The Canadian journal of cardiology 20041001
Title: Eprosartan mesylate effectively reduces systolic and diastolic blood pressure in a Canadian primary care setting.
Journal: The Canadian journal of cardiology 20041001
Title: The angiotensin receptor blocker eprosartan mesylate reduces pulse pressure in isolated systolic hypertension.
Journal: The Canadian journal of cardiology 20041001
Title: The effect of treatment with eprosartan on pulse pressure: factors predicting response.
Journal: The Canadian journal of cardiology 20041001
Title: Once-daily eprosartan mesylate in the treatment of elderly patients with isolated systolic hypertension: data from a 13-week double-blind, placebo-controlled, parallel, multicenter study.
Journal: Journal of human hypertension 20040901
Title: Effect of eprosartan on cytoplasmic free calcium mobilization, platelet activation, and microparticle formation in hypertension.
Journal: American journal of hypertension 20040901
Title: Effects of telmisartan compared with eprosartan on blood pressure control, glucose metabolism and lipid profile in hypertensive, type 2 diabetic patients: a randomized, double-blind, placebo-controlled 12-month study.
Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20040701
Title: A double blind randomized trial to compare the effects of eprosartan and enalapril on blood pressure, platelets, and endothelium function in patients with essential hypertension.
Journal: Japanese heart journal 20040701
Title: Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity.
Journal: Circulation 20040504
Title: [Anti-hypertensive effect of eprosartan in diabetic patients].
Journal: Anales de medicina interna (Madrid, Spain : 1984) 20040501
Title: Re: Heusser et al: elevation of sympathetic activity by eprosartan in young male subjects.
Journal: American journal of hypertension 20040301
Title: Eprosartan improves cardiac performance, reduces cardiac hypertrophy and mortality and downregulates myocardial monocyte chemoattractant protein-1 and inflammation in hypertensive heart disease.
Journal: Journal of hypertension 20040301
Title: Different prejunctional and postjunctional responses to angiotensin II and AT1-receptor inhibition: influence of maturation.
Journal: Journal of cardiovascular pharmacology 20040301
Title: Heat shock treatment protects against angiotensin II-induced hypertension and inflammation in aorta.
Journal: Cell stress & chaperones 20040301
Title: Potential renoprotective effects of the angiotensin receptor blocker eprosartan: a review of preliminary renal studies.
Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20040101
Title: [Effect of eprosartan on microcirculation and blood rheology in patients with hypertensive disease].
Journal: Kardiologiia 20040101
Title: [Comparison of eprosartan and captopril in left ventricular systolic dysfunction: relation of efficacy to myocardial viability].
Journal: Kardiologiia 20040101
Title: [Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of pharmacology and experience of use in arterial hypertension].
Journal: Kardiologiia 20040101
Title: Eprosartan dual action offers clinical benefit for elderly and overweight hypertensives.
Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20040101
Title: Eprosartan effect on fibrinolytic/hemostatic variables in arterial hypertension: a comparative study to losartan.
Journal: Drugs under experimental and clinical research 20040101
Title: Teveten (eprosartan) reduces future risk in hypertensive stroke patients.
Journal: Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners 20040101
Title: [Elevation pressure in morning hours in patients with essential hypertension: effect therapy with eprosartan for leading stress tests].
Journal: Kardiologiia 20040101
Title: Renal damage is not improved by blockade of endothelin receptors in primary renin-dependent hypertension.
Journal: Journal of hypertension 20031201
Title: Impaired neuronal and vascular responses to angiotensin II in a rabbit congestive heart failure model.
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Title: [Dosage equivalents of AT1-receptor antagonists available in Germany].
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Title: [Theoretical background of angiotensin II receptor blockade and its features in clinical pharmacology].
Journal: Orvosi hetilap 20030907
Title: AT1 antagonism by eprosartan lowers heart rate variability and baroreflex gain.
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Title: Elevation of sympathetic activity by eprosartan in young male subjects.
Journal: American journal of hypertension 20030801
Title: [When the goal values are more than 20/10 mmHg distant. High blood pressure is to be forced down from two sides immediately].
Journal: MMW Fortschritte der Medizin 20030710
Title: Cardiology patient page. Angiotensin receptor blockers.
Journal: Circulation 20030624
Title: Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites.
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Title: Pre- and postsynaptic inhibitory potencies of the angiotensin AT1 receptor antagonists eprosartan and candesartan.
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Title: Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification.
Journal: Journal of medicinal chemistry 20030227
Title: Effects of isosorbide mononitrate and AII inhibition on pulse wave reflection in hypertension.
Journal: Hypertension (Dallas, Tex. : 1979) 20030201
Title: Effects of angiotensin II receptor antagonism on the renal hemodynamic response to cardiovascular stress.
Journal: Kidney international 20030201
Title: Eprosartan for the treatment of hypertension.
Journal: Expert opinion on pharmacotherapy 20030101
Title: Effects of the AT1-receptor antagonist eprosartan on the progression of left ventricular dysfunction in dogs with heart failure.
Journal: British journal of pharmacology 20030101
Title: [Neurocirculatory dystonia (does this disease exist?)].
Journal: Kardiologiia 20030101
Title: [Antihypertensive treatment with eprosartan mesilate of patients in acute and late periods of ischemic stroke].
Journal: Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20030101
Title: Emerging role of angiotensin II type 1 receptor blockers for the treatment of endothelial dysfunction and vascular inflammation.
Journal: The Canadian journal of cardiology 20021201
Title: Clinical profile of eprosartan.
Journal: Cardiovascular drugs and therapy 20021201
Title: Drug points: Dysgeusia and burning mouth syndrome by eprosartan.
Journal: BMJ (Clinical research ed.) 20021130
Title: Prejunctional and postjunctional inhibitory actions of eprosartan and candesartan in the isolated rabbit mesenteric artery.
Journal: Journal of cardiovascular pharmacology 20020701
Title: Angiotensin converting enzyme inhibition and angiotensin II AT1-receptor blockade reduce the levels of asymmetrical N(G), N(G)-dimethylarginine in human essential hypertension.
Journal: American journal of hypertension 20020701
Title: [Therapy of hypertension. Why the systolic value is decisive].
Journal: MMW Fortschritte der Medizin 20020606
Title: AT1 blockers and uric acid metabolism: are there relevant differences?
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Title: The clinical profile of the angiotensin II receptor blocker eprosartan.
Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20020601
Title: [Irbesartan: a new possibility in the treatment of hypertension].
Journal: Orvosi hetilap 20020526
Title: Structure elucidation and conformational properties of eprosartan, a non peptide angiotensin II AT1 antagonist.
Journal: Journal of pharmaceutical and biomedical analysis 20020401
Title: The angiotensin type 1 receptor antagonist, eprosartan, attenuates the progression of renal disease in spontaneously hypertensive stroke-prone rats with accelerated hypertension.
Journal: The Journal of pharmacology and experimental therapeutics 20020401
Title: Effects of enalapril and eprosartan on the renal vascular nitric oxide system in human essential hypertension.
Journal: Kidney international 20020401
Title: Effects of eprosartan versus hydrochlorothiazide on markers of vascular oxidation and inflammation and blood pressure (renin-angiotensin system antagonists, oxidation, and inflammation).
Journal: The American journal of cardiology 20020315
Title: Brain angiotensinergic mediation of enhanced water consumption in lactating rats.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020301
Title: Efficacy of eprosartan in combination with HCTZ in patients with essential hypertension.
Journal: Journal of human hypertension 20020301
Title: Application of capillary zone electrophoresis to the screening of some angiotensin II receptor antagonists.
Journal: Electrophoresis 20020101
Title: [Significance of pharmacological blockade of angiotensin II type I receptors for correction of abnormal 24-hour blood pressure profile depending on its variability in patients with arterial hypertension stage II].
Journal: Terapevticheskii arkhiv 20020101
Title: Eprosartan: an angiotensin-II receptor antagonist for the management of hypertension.
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Title: Safety and tolerability of eprosartan in combination with hydrochlorothiazide.
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Title: [Policy of antihypertensive therapy in arterial hypertension in the elderly. II].
Journal: Klinicheskaia meditsina 20020101
Title: [Effect of eprosartan on left ventricular diastolic function and cerebral hemodynamics in patients with hypertension].
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Title: [Metabolic effects of angiotensin-II receptor blockers].
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Title: Inhibition of facilitation of sympathetic neurotransmission and angiotensin II-induced pressor effects in the pithed rat: comparison between valsartan, candesartan, eprosartan and embusartan.
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Title: Intrarenal angiotensin II: interstitial and cellular levels and site of production.
Journal: Kidney international 20011201
Title: Comparison of quality of life and cough on eprosartan and enalapril in people with moderate hypertension.
Journal: Journal of human hypertension 20011201
Title: Quality of life and cough on antihypertensive treatment: a randomised trial of eprosartan, enalapril and placebo.
Journal: Journal of human hypertension 20011201
Title: Evaluation of the 24-hour blood pressure effects of eprosartan in patients with systemic hypertension.
Journal: American journal of hypertension 20011201
Title: Angiotensin II antagonists in systolic blood pressure control.
Journal: Hospital medicine (London, England : 1998) 20011201
Title: Differentiation in the angiotensin II receptor 1 blocker class on autonomic function.
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Title: Potential of the angiotensin II receptor 1 blocker eprosartan in the management of patients with hypertension or heart failure.
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Title: Issues in hypertension: drug tolerability and special populations.
Journal: American journal of hypertension 20010701
Title: Pharmacology and clinical efficacy of angiotensin receptor blockers.
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Title: Eprosartan reduces cardiac hypertrophy, protects heart and kidney, and prevents early mortality in severely hypertensive stroke-prone rats.
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Title: Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi*--pi* interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists.
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Title: Differential effects of eprosartan and losartan at prejunctional angiotensin II receptors.
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