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1332391-11-3
Catalog No.:AA01NV4Z

1332391-11-3 | N-Desmethyl-Apalutamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$284.00   $199.00
- +
5mg
95%
1 week  
$578.00   $404.00
- +
10mg
95%
1 week  
$808.00   $566.00
- +
25mg
95%
1 week  
$1,186.00   $830.00
- +
50mg
95%
1 week  
$1,612.00   $1,128.00
- +
100mg
95%
1 week  
$2,149.00   $1,504.00
- +
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  • Technical Information
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Technical Information
Catalog Number:
AA01NV4Z
Chemical Name:
N-Desmethyl-Apalutamide
CAS Number:
1332391-11-3
Molecular Formula:
C20H13F4N5O2S
Molecular Weight:
463.4081
SMILES:
N#Cc1ncc(cc1C(F)(F)F)N1C(=S)N(C2(C1=O)CCC2)c1ccc(c(c1)F)C(=O)N
Properties

Literature

Title: Pérez-Ruixo C, et al. Population Pharmacokinetics of Apalutamide and its Active Metabolite N-Desmethyl-Apalutamide in Healthy and Castration-Resistant Prostate Cancer Subjects. Clin Pharmacokinet. 2019 Aug 20.

Title: Smith MR, et al. Phase 2 Study of the Safety and Antitumor Activity of Apalutamide (ARN-509), a Potent Androgen Receptor Antagonist, in the High-risk Nonmetastatic Castration-resistant Prostate Cancer Cohort. Eur Urol. 2016 May 6. pii: S0302-2838(16)30133

Title: May MB, et al. Apalutamide: A new agent in the management of prostate cancer. J Oncol Pharm Pract. 2019 Dec;25(8):1968-1978.

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SDS
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Tags:1332391-11-3 Molecular Formula|1332391-11-3 MDL|1332391-11-3 SMILES|1332391-11-3 N-Desmethyl-Apalutamide