Title: Arsenic-induced apoptosis in the p53-proficient and p53-deficient cells through differential modulation of NFkB pathway.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180801
Title: Compensatory role of the Nrf2-ARE pathway against paraquat toxicity: Relevance of 26S proteasome activity.
Journal: Journal of pharmacological sciences 20151101
Title: The Food-Associated Ribotoxin Deoxynivalenol Modulates Inducible NO Synthase in Human Intestinal Cell Model.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150601
Title: Beta catenin is degraded by both caspase-3 and proteasomal activity during resveratrol-induced apoptosis in HeLa cells in a GSK3β-independent manner.
Journal: Indian journal of biochemistry & biophysics 20150201
Title: Resveratrol promotes degradation of the human bile acid transporter ASBT (SLC10A2).
Journal: The Biochemical journal 20140415
Title: Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor.
Journal: The Biochemical journal 20140215
Title: Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells.
Journal: PloS one 20140101
Title: Forskolin stimulation promotes urea transporter UT-A1 ubiquitination, endocytosis, and degradation in MDCK cells.
Journal: American journal of physiology. Renal physiology 20121101
Title: Δ⁹-tetrahydrocannabinol (Δ⁹-THC) exerts a direct neuroprotective effect in a human cell culture model of Parkinson's disease.
Journal: Neuropathology and applied neurobiology 20121001
Title: Chaperones, but not oxidized proteins, are ubiquitinated after oxidative stress.
Journal: Free radical biology & medicine 20121001
Title: Proteasome inhibition decreases inflammation in human endothelial cells exposed to lipopolysaccharide.
Journal: Journal of cardiovascular pharmacology 20121001
Title: [Enhanced activation of T lymphocytes by urease-deficient recombinant bacillus Calmette-Guérin producing heat shock protein 70-major membrane protein-II fusion protein].
Journal: Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20120901
Title: Expression of the ubiquitin proteasome system in neonatal rat gonocytes and spermatogonia: role in gonocyte differentiation.
Journal: Biology of reproduction 20120801
Title: Laminin-111 stimulates proliferation of mouse embryonic stem cells through a reduction of gap junctional intercellular communication via RhoA-mediated Cx43 phosphorylation and dissociation of Cx43/ZO-1/drebrin complex.
Journal: Stem cells and development 20120720
Title: Ubiquitin-proteasome system inhibitors and AMPK regulation in hepatic cold ischaemia and reperfusion injury: possible mechanisms.
Journal: Clinical science (London, England : 1979) 20120701
Title: Lys(203) and Lys(382) are essential for the proteasomal degradation of BACE1.
Journal: Current Alzheimer research 20120601
Title: Differential degradation of full-length and cleaved ataxin-7 fragments in a novel stable inducible SCA7 model.
Journal: Journal of molecular neuroscience : MN 20120601
Title: Increased expression of α-synuclein by SNCA duplication is associated with resistance to toxic stimuli.
Journal: Journal of molecular neuroscience : MN 20120601
Title: Diltiazem enhances the apoptotic effects of proteasome inhibitors to induce prostate cancer cell death.
Journal: The Journal of pharmacology and experimental therapeutics 20120601
Title: The effect of the NF-kappa B inhibitors curcumin and lactacystin on myogenic differentiation of rhabdomyosarcoma cells.
Journal: Differentiation; research in biological diversity 20120601
Title: The regulation of N-terminal Huntingtin (Htt552) accumulation by Beclin1.
Journal: Acta pharmacologica Sinica 20120601
Title: Diphenylarsinic acid promotes degradation of glutaminase C by mitochondrial Lon protease.
Journal: The Journal of biological chemistry 20120525
Title: Human tau may modify glucocorticoids-mediated regulation of cAMP-dependent kinase and phosphorylated cAMP response element binding protein.
Journal: Neurochemical research 20120501
Title: P53 and the proteasome regulate androgen receptor activity.
Journal: Cancer biology & therapy 20120501
Title: High sensitivity of embryonic stem cells to proteasome inhibitors correlates with low expression of heat shock protein and decrease of pluripotent cell marker expression.
Journal: BMB reports 20120501
Title: Design and synthesis of naphthoquinone derivatives as antiproliferative agents and 20S proteasome inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20120415
Title: The plasma membrane redox enzyme NQO1 sustains cellular energetics and protects human neuroblastoma cells against metabolic and proteotoxic stress.
Journal: Age (Dordrecht, Netherlands) 20120401
Title: Effects of phosphatase and proteasome inhibitors on Borealin phosphorylation and degradation.
Journal: Journal of biochemistry 20120401
Title: A critical role for the inducible proteasomal subunits LMP7 and MECL1 in cytokine production by activated murine splenocytes.
Journal: Pharmacology 20120401
Title: Proteasomal inhibition restores biological function of mis-sense mutated dysferlin in patient-derived muscle cells.
Journal: The Journal of biological chemistry 20120323
Title: Met kinase-dependent loss of the E3 ligase Cbl in gastric cancer.
Journal: The Journal of biological chemistry 20120309
Title: TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases.
Journal: Journal of cellular physiology 20120301
Title: Modeling mitochondrial dysfunctions in the brain: from mice to men.
Journal: Journal of inherited metabolic disease 20120301
Title: Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.
Journal: Biochimie 20120301
Title: Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase.
Journal: Journal of cell science 20120301
Title: An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid.
Journal: Nature communications 20120221
Title: Peroxisome proliferator-activated receptor-γ activation reduces cyclooxygenase-2 expression in vascular smooth muscle cells from hypertensive rats by interfering with oxidative stress.
Journal: Journal of hypertension 20120201
Title: Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade.
Journal: PLoS pathogens 20120201
Title: p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells.
Journal: PLoS biology 20120201
Title: The peptidases of Trypanosoma cruzi: digestive enzymes, virulence factors, and mediators of autophagy and programmed cell death.
Journal: Biochimica et biophysica acta 20120101
Title: Janus kinase 2--a novel negative regulator of estrogen receptor α function.
Journal: Cellular signalling 20120101
Title: Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1.
Journal: The Biochemical journal 20120101
Title: gp130 cytokines stimulate proteasomal degradation of tyrosine hydroxylase via extracellular signal regulated kinases 1 and 2.
Journal: Journal of neurochemistry 20120101
Title: Chromatin remodelling protein SMAR1 inhibits p53 dependent transactivation by regulating acetyl transferase p300.
Journal: The international journal of biochemistry & cell biology 20120101
Title: Effects of proteasome inhibitors on the nucleolar size of porcine oocytes.
Journal: The Journal of reproduction and development 20120101
Title: Functional processing of nuclear Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP-N): evidence for a critical role of proteolytic processing in the regulation of its catalytic activity, subcellular localization and substrate targeting in vivo.
Journal: Archives of biochemistry and biophysics 20120101
Title: M30, a brain permeable multitarget neurorestorative drug in post nigrostriatal dopamine neuron lesion of parkinsonism animal models.
Journal: Parkinsonism & related disorders 20120101
Title: Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum.
Journal: PloS one 20120101
Title: Human papillomavirus 18 E6 inhibits phosphorylation of p53 expressed in HeLa cells.
Journal: Cell & bioscience 20120101
Title: Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity.
Journal: Cell death & disease 20120101
Title: Translation of MMTV Gag requires nuclear events involving splicing motifs in addition to the viral Rem protein and RmRE.
Journal: Retrovirology 20120101
Title: Mammalian ste20-like kinase and SAV1 promote 3T3-L1 adipocyte differentiation by activation of PPARγ.
Journal: PloS one 20120101
Title: Protein carbonylation and aggregation precede neuronal apoptosis induced by partial glutathione depletion.
Journal: ASN neuro 20120101
Title: Internalization and down-regulation of the ALK receptor in neuroblastoma cell lines upon monoclonal antibodies treatment.
Journal: PloS one 20120101
Title: Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS.
Journal: PloS one 20120101
Title: Differential regulation of cutaneous oncoprotein HPVE6 by wtp53, mutant p53R248W and ΔNp63α is HPV type dependent.
Journal: PloS one 20120101
Title: Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6.
Journal: PloS one 20120101
Title: Engagement of ubiquitination and de-ubiquitination at rostral ventrolateral medulla in experimental brain death.
Journal: Journal of biomedical science 20120101
Title: Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus.
Journal: Journal of neuroinflammation 20120101
Title: Escape from the Phagosome: The Explanation for MHC-I Processing of Mycobacterial Antigens?
Journal: Frontiers in immunology 20120101
Title: Cross-presentation of cell-associated antigens by mouse splenic dendritic cell populations.
Journal: Frontiers in immunology 20120101
Title: Nicotinic acetylcholine receptor agonists attenuate septic acute kidney injury in mice by suppressing inflammation and proteasome activity.
Journal: PloS one 20120101
Title: Phosphorylation of nicastrin by SGK1 leads to its degradation through lysosomal and proteasomal pathways.
Journal: PloS one 20120101
Title: MAVS ubiquitination by the E3 ligase TRIM25 and degradation by the proteasome is involved in type I interferon production after activation of the antiviral RIG-I-like receptors.
Journal: BMC biology 20120101
Title: Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2.
Journal: PloS one 20120101
Title: Novel strategies for immunotherapy in multiple myeloma: previous experience and future directions.
Journal: Clinical & developmental immunology 20120101
Title: AMPA receptor trafficking in homeostatic synaptic plasticity: functional molecules and signaling cascades.
Journal: Neural plasticity 20120101
Title: Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer.
Journal: PloS one 20120101
Title: Release of Full-Length PrP(C) from Cultured Neurons Following Neurotoxic Challenges.
Journal: Frontiers in neurology 20120101
Title: γ-Secretase and presenilin mediate cleavage and phosphorylation of vascular endothelial growth factor receptor-1.
Journal: The Journal of biological chemistry 20111209
Title: p53-Independent up-regulation of a TRAIL receptor DR5 by proteasome inhibitors: a mechanism for proteasome inhibitor-enhanced TRAIL-induced apoptosis.
Journal: Biochemical and biophysical research communications 20111209
Title: Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cells.
Journal: Biochemical and biophysical research communications 20111202
Title: Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons.
Journal: Neurotoxicology 20111201
Title: Proteasome inhibitor lactacystin augments natural killer cell cytotoxicity of myeloma via downregulation of HLA class I.
Journal: Biochemical and biophysical research communications 20111111
Title: TRAIL promotes caspase-dependent pro-inflammatory responses via PKCδ activation by vascular smooth muscle cells.
Journal: Cell death & disease 20111101
Title: Stereospecific total syntheses of proteasome inhibitors omuralide and lactacystin.
Journal: The Journal of organic chemistry 20111021
Title: P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism.
Journal: Oncogene 20111013
Title: Protection of neuronal calcium sensor 1 protein in cells treated with paclitaxel.
Journal: The Journal of biological chemistry 20111007
Title: Nrf2/HO-1 pathway activation by manganese is associated with reactive oxygen species and ubiquitin-proteasome pathway, not MAPKs signaling.
Journal: Journal of applied toxicology : JAT 20111001
Title: Animal models of Parkinson's disease: a source of novel treatments and clues to the cause of the disease.
Journal: British journal of pharmacology 20111001
Title: New betulinic acid derivatives as potent proteasome inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20111001
Title: Chlamydia trachomatis co-opts the FGF2 signaling pathway to enhance infection.
Journal: PLoS pathogens 20111001
Title: RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity.
Journal: The Journal of biological chemistry 20110916
Title: The human papillomavirus E6 oncogene represses a cell adhesion pathway and disrupts focal adhesion through degradation of TAp63β upon transformation.
Journal: PLoS pathogens 20110901
Title: Targeting of a chlamydial protease impedes intracellular bacterial growth.
Journal: PLoS pathogens 20110901
Title: Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta.
Journal: The Journal of biological chemistry 20110819
Title: [Expression and regulation of androgen receptor in the androgen-independent conversion of prostate cancer cells].
Journal: Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20110818
Title: Crosstalk between Nodal/activin and MAPK p38 signaling is essential for anterior-posterior axis specification.
Journal: Current biology : CB 20110809
Title: Changes in iron-regulatory gene expression occur in human cell culture models of Parkinson's disease.
Journal: Neurochemistry international 20110801
Title: Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase.
Journal: Parasitology 20110801
Title: The Parkinson's disease protein LRRK2 impairs proteasome substrate clearance without affecting proteasome catalytic activity.
Journal: Cell death & disease 20110801
Title: Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.
Journal: PLoS pathogens 20110801
Title: γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage.
Journal: Chemical research in toxicology 20110718
Title: Novel cell- and tissue-based assays for detecting misfolded and aggregated protein accumulation within aggresomes and inclusion bodies.
Journal: Cell biochemistry and biophysics 20110701
Title: Proteasomal degradation of myocardin is required for its transcriptional activity in vascular smooth muscle cells.
Journal: Journal of cellular physiology 20110701
Title: [Content of chaperon Hsp70 in dopaminergic neurons of the black substance increases in proteasome dysfunstion].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20110701
Title: Valosin-containing protein gene mutations: cellular phenotypes relevant to neurodegeneration.
Journal: Journal of molecular neuroscience : MN 20110601
Title: PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.
Journal: American journal of physiology. Cell physiology 20110601
Title: LPS-induced formation of immunoproteasomes: TNF-α and nitric oxide production are regulated by altered composition of proteasome-active sites.
Journal: Cell biochemistry and biophysics 20110601
Title: Identification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells.
Journal: PLoS pathogens 20110601
Title: Mitogen-activated protein kinase kinase 1 (MEK1) stabilizes MyoD through direct phosphorylation at tyrosine 156 during myogenic differentiation.
Journal: The Journal of biological chemistry 20110527
Title: The role of the proteasome in the generation of MHC class I ligands and immune responses.
Journal: Cellular and molecular life sciences : CMLS 20110501
Title: Functional 20S proteasomes in mature human red blood cells.
Journal: Experimental biology and medicine (Maywood, N.J.) 20110501
Title: [Effect of epigallocatechin gallate on lactacystin-induced PC12 cell injury].
Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20110501
Title: Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis.
Journal: Experimental cell research 20110415
Title: Semi-high throughput method of measuring proteasome inhibition in vitro and in cultured cells.
Journal: Cell biology and toxicology 20110401
Title: Lactacystin, a proteasome inhibitor, enhances BMP-induced osteoblastic differentiation by increasing active Smads.
Journal: Biochemical and biophysical research communications 20110401
Title: Synthesis and proteasome inhibition of lithocholic acid derivatives.
Journal: Bioorganic & medicinal chemistry letters 20110401
Title: Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling.
Journal: Cell 20110401
Title: The neuroprotective effect of modified Yeoldahanso-tang via autophagy enhancement in models of Parkinson's disease.
Journal: Journal of ethnopharmacology 20110324
Title: Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation.
Journal: The Journal of biological chemistry 20110318
Title: Opioid-induced down-regulation of RGS4: role of ubiquitination and implications for receptor cross-talk.
Journal: The Journal of biological chemistry 20110311
Title: Does 1-(R)-aminoindan possess neuroprotective properties against experimental Parkinson's disease?
Journal: Antioxidants & redox signaling 20110301
Title: Long-term aversive taste memory requires insular and amygdala protein degradation.
Journal: Neurobiology of learning and memory 20110301
Title: Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis.
Journal: Cell death & disease 20110301
Title: A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system.
Journal: PLoS pathogens 20110301
Title: The role of monoubiquitination in endocytic degradation of human ether-a-go-go-related gene (hERG) channels under low K+ conditions.
Journal: The Journal of biological chemistry 20110225
Title: Transcription factor IIS cooperates with the E3 ligase UBR5 to ubiquitinate the CDK9 subunit of the positive transcription elongation factor B.
Journal: The Journal of biological chemistry 20110218
Title: Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability.
Journal: Oncogene 20110217
Title: Processing of optineurin in neuronal cells.
Journal: The Journal of biological chemistry 20110204
Title: Up-regulation of endoplasmic reticulum stress-related genes during the early phase of treatment of cultured cortical neurons by the proteasomal inhibitor lactacystin.
Journal: Journal of cellular physiology 20110201
Title: Pathogenic VCP/TER94 alleles are dominant actives and contribute to neurodegeneration by altering cellular ATP level in a Drosophila IBMPFD model.
Journal: PLoS genetics 20110201
Title: What has the study of the K3 and K5 viral ubiquitin E3 ligases taught us about ubiquitin-mediated receptor regulation?
Journal: Viruses 20110201
Title: Tripeptidyl peptidase II serves as an alternative to impaired proteasome to maintain viral growth in the host cells.
Journal: FEBS letters 20110103
Title: Glucocorticoid-induced activation of caspase-8 protects the glucocorticoid-induced protein Gilz from proteasomal degradation and induces its binding to SUMO-1 in murine thymocytes.
Journal: Cell death and differentiation 20110101
Title: Wnt3a regulates tumor necrosis factor-α-stimulated interleukin-6 release in osteoblasts.
Journal: Molecular and cellular endocrinology 20110101
Title: Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms.
Journal: Environmental health perspectives 20110101
Title: Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathways.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101
Title: Inhibition of all-trans-retinoic acid-induced proteasome activation potentiates the differentiating effect of retinoid in acute myeloid leukemia cells.
Journal: Molecular carcinogenesis 20110101
Title: β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency.
Journal: Diabetes 20110101
Title: Regulation of posttranscriptional modification as a possible therapeutic approach for retinal neuroprotection.
Journal: Journal of ophthalmology 20110101
Title: Effects of proteasome inhibitors on rat renal fibrosis in vitro and in vivo.
Journal: Nephrology (Carlton, Vic.) 20110101
Title: Steroids up-regulate p66Shc longevity protein in growth regulation by inhibiting its ubiquitination.
Journal: PloS one 20110101
Title: Perturbation with intrabodies reveals that calpain cleavage is required for degradation of huntingtin exon 1.
Journal: PloS one 20110101
Title: The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease.
Journal: International journal of molecular sciences 20110101
Title: Senescence marker protein 30 (SMP30) expression in eukaryotic cells: existence of multiple species and membrane localization.
Journal: PloS one 20110101
Title: Evolution of extra-nigral damage predicts behavioural deficits in a rat proteasome inhibitor model of Parkinson's disease.
Journal: PloS one 20110101
Title: Thiazole antibiotic thiostrepton synergize with bortezomib to induce apoptosis in cancer cells.
Journal: PloS one 20110101
Title: Resveratrol protects leukemic cells against cytotoxicity induced by proteasome inhibitors via induction of FOXO1 and p27Kip1.
Journal: BMC cancer 20110101
Title: Trafficking defect and proteasomal degradation contribute to the phenotype of a novel KCNH2 long QT syndrome mutation.
Journal: PloS one 20110101
Title: A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 1.
Journal: PloS one 20110101
Title: Photodynamic treatment induces an apoptotic pathway involving calcium, nitric oxide, p53, p21-activated kinase 2, and c-Jun N-terminal kinase and inactivates survival signal in human umbilical vein endothelial cells.
Journal: International journal of molecular sciences 20110101
Title: Inverse baseline expression pattern of the NEP/neuropeptides and NFκB/proteasome pathways in androgen-dependent and androgen-independent prostate cancer cells.
Journal: Cancer cell international 20110101
Title: HGF/c-met/Stat3 signaling during skin tumor cell invasion: indications for a positive feedback loop.
Journal: BMC cancer 20110101
Title: Firefly luciferase and RLuc8 exhibit differential sensitivity to oxidative stress in apoptotic cells.
Journal: PloS one 20110101
Title: C-terminus glycans with critical functional role in the maturation of secretory glycoproteins.
Journal: PloS one 20110101
Title: Reduction of mutant huntingtin accumulation and toxicity by lysosomal cathepsins D and B in neurons.
Journal: Molecular neurodegeneration 20110101
Title: Parkin, A Top Level Manager in the Cell's Sanitation Department.
Journal: The open biochemistry journal 20110101
Title: p21(WAF1/CIP1) upregulation through the stress granule-associated protein CUGBP1 confers resistance to bortezomib-mediated apoptosis.
Journal: PloS one 20110101
Title: Negative regulation of interferon-β gene expression during acute and persistent virus infections.
Journal: PloS one 20110101
Title: NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.
Journal: Breast cancer research : BCR 20110101
Title: Analysis of proteasomal proteolysis during the in vitro metacyclogenesis of Trypanosoma cruzi.
Journal: PloS one 20110101
Title: The p53 tumor suppressor is stabilized by inhibitor of growth 1 (ING1) by blocking polyubiquitination.
Journal: PloS one 20110101
Title: The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells.
Journal: Molecular cancer 20110101
Title: Eeyarestatin 1 interferes with both retrograde and anterograde intracellular trafficking pathways.
Journal: PloS one 20110101
Title: Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons.
Journal: PloS one 20110101
Title: CDK5 is essential for soluble amyloid β-induced degradation of GKAP and remodeling of the synaptic actin cytoskeleton.
Journal: PloS one 20110101
Title: Betulinic acid inhibits colon cancer cell and tumor growth and induces proteasome-dependent and -independent downregulation of specificity proteins (Sp) transcription factors.
Journal: BMC cancer 20110101
Title: Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4.
Journal: Molecular cancer 20110101
Title: Protein C mutation (A267T) results in ER retention and unfolded protein response activation.
Journal: PloS one 20110101
Title: SVIP induces localization of p97/VCP to the plasma and lysosomal membranes and regulates autophagy.
Journal: PloS one 20110101
Title: In vivo RNAi screen reveals neddylation genes as novel regulators of Hedgehog signaling.
Journal: PloS one 20110101
Title: Human metapneumovirus inhibits IFN-β signaling by downregulating Jak1 and Tyk2 cellular levels.
Journal: PloS one 20110101
Title: The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation.
Journal: Molecular systems biology 20110101
Title: A ubiquitin independent degradation pathway utilized by a hepatitis B virus envelope protein to limit antigen presentation.
Journal: PloS one 20110101
Title: Suppression of nitric oxide induction and pro-inflammatory cytokines by novel proteasome inhibitors in various experimental models.
Journal: Lipids in health and disease 20110101
Title: The docking protein p130Cas regulates cell sensitivity to proteasome inhibition.
Journal: BMC biology 20110101
Title: Hakai reduces cell-substratum adhesion and increases epithelial cell invasion.
Journal: BMC cancer 20110101
Title: Substrate-favored lysosomal and proteasomal pathways participate in the normal balance control of insulin precursor maturation and disposal in β-cells.
Journal: PloS one 20110101
Title: A double-edged sword role for ubiquitin-proteasome system in brain stem cardiovascular regulation during experimental brain death.
Journal: PloS one 20110101
Title: Amorphous silica nanoparticles trigger nitric oxide/peroxynitrite imbalance in human endothelial cells: inflammatory and cytotoxic effects.
Journal: International journal of nanomedicine 20110101
Title: Postnatal proteasome inhibition induces neurodegeneration and cognitive deficiencies in adult mice: a new model of neurodevelopment syndrome.
Journal: PloS one 20110101
Title: Inhibition of nitric oxide in LPS-stimulated macrophages of young and senescent mice by δ-tocotrienol and quercetin.
Journal: Lipids in health and disease 20110101
Title: Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells.
Journal: Oncology 20110101
Title: The Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxia.
Journal: PloS one 20110101
Title: The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase.
Journal: PloS one 20110101
Title: Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.
Journal: The Journal of biological chemistry 20101224
Title: Cell cycle events mediate lactacystin-induced apoptotic death of neuronal PC12 cells.
Journal: Cell biology international 20101201
Title: Manganese-induced downregulation of astroglial glutamine transporter SNAT3 involves ubiquitin-mediated proteolytic system.
Journal: Glia 20101201
Title: Identification of p10 as a neurotoxic product generated from the proteolytic cleavage of the neuronal Cdk5 activator.
Journal: Journal of cellular biochemistry 20101201
Title: Metabolism and action of proteasome inhibitors in primary human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: NleC, a type III secretion protease, compromises NF-κB activation by targeting p65/RelA.
Journal: PLoS pathogens 20101201
Title: Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cells.
Journal: Aging 20101201
Title: Ammonium chloride and tunicamycin are novel toxins for dopaminergic neurons and induce Parkinson's disease-like phenotypes in medaka fish.
Journal: Journal of neurochemistry 20101201
Title: TGF-β induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid β plaques in Alzheimer's disease.
Journal: Cell death & disease 20101201
Title: [Sleep changes during degeneration of neurons in the substantia nigra induced by inhibitor of proteasomes lactacystin in rats].
Journal: Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20101201
Title: Selective susceptibility of human dopaminergic neural stem cells to dopamine-induced apoptosis.
Journal: Experimental neurobiology 20101201
Title: Identification of a lysosomal pathway regulating degradation of the bone morphogenetic protein receptor type II.
Journal: The Journal of biological chemistry 20101126
Title: Annexin A3 is associated with cell death in lactacystin-mediated neuronal injury.
Journal: Neuroscience letters 20101119
Title: Enhanced activation of T lymphocytes by urease-deficient recombinant bacillus Calmette-Guérin producing heat shock protein 70-major membrane protein-II fusion protein.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20101115
Title: Fatty acids regulate CREBh via transcriptional mechanisms that are dependent on proteasome activity and insulin.
Journal: Molecular and cellular biochemistry 20101101
Title: HTLV-1 evades type I interferon antiviral signaling by inducing the suppressor of cytokine signaling 1 (SOCS1).
Journal: PLoS pathogens 20101101
Title: Synthesis of α-amino acids based on chiral tricycloiminolactone derived from natural (+)-camphor.
Journal: Accounts of chemical research 20101019
Title: The proteasome regulates bacterial CpG DNA-induced signaling pathways in murine macrophages.
Journal: Shock (Augusta, Ga.) 20101001
Title: Expression of alternatively spliced CD45 isoforms by channel catfish clonal T and B cells is dependent on activation state of the cell and regulated by protein synthesis and degradation.
Journal: Developmental and comparative immunology 20101001
Title: Neuroprotection of pramipexole in UPS impairment induced animal model of Parkinson's disease.
Journal: Neurochemical research 20101001
Title: Proteasome inhibition in medaka brain induces the features of Parkinson's disease.
Journal: Journal of neurochemistry 20101001
Title: Proteasome inhibition modeling nigral neuron degeneration in Parkinson's disease.
Journal: Journal of neurochemistry 20101001
Title: Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit.
Journal: The Biochemical journal 20100915
Title: ARRDC3 suppresses breast cancer progression by negatively regulating integrin beta4.
Journal: Oncogene 20100909
Title: p53 Plays an important role in cell fate determination after exposure to microcystin-LR.
Journal: Environmental health perspectives 20100901
Title: Cbl-b enhances Runx2 protein stability and augments osteocalcin promoter activity in osteoblastic cell lines.
Journal: Journal of cellular physiology 20100901
Title: Effect of nuclear factor kappa B inhibition on L-NAME-induced hypertension and cardiovascular remodelling.
Journal: Journal of hypertension 20100901
Title: Low levels of mutant ubiquitin are degraded by the proteasome in vivo.
Journal: Journal of neuroscience research 20100815
Title: Novel D3 dopamine receptor-preferring agonist D-264: Evidence of neuroprotective property in Parkinson's disease animal models induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and lactacystin.
Journal: Journal of neuroscience research 20100815
Title: Anthrax lethal toxin activates the inflammasome in sensitive rat macrophages.
Journal: Biochemical and biophysical research communications 20100806
Title: Proapoptotic fibronectin fragment induces the degradation of ubiquitinated p53 via proteasomes in periodontal ligament cells.
Journal: Journal of periodontal research 20100801
Title: Estrogen receptor beta signaling through phosphatase and tensin homolog/phosphoinositide 3-kinase/Akt/glycogen synthase kinase 3 down-regulates blood-brain barrier breast cancer resistance protein.
Journal: The Journal of pharmacology and experimental therapeutics 20100801
Title: The forced aggresome formation of a bovine anion exchanger 1 (AE1) mutant through association with δF508-cystic fibrosis transmembrane conductance regulator upon proteasome inhibition in HEK293 cells.
Journal: The Japanese journal of veterinary research 20100801
Title: Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1,N2-gamma-hydroxypropanodeoxyguanosine lesion with a trimethylene linkage.
Journal: Biochemistry 20100727
Title: Regulation of aurora B kinase by the lipid raft protein flotillin-1.
Journal: The Journal of biological chemistry 20100702
Title: Determinants of CREB degradation and KChIP2 gene transcription in cardiac memory.
Journal: Heart rhythm 20100701
Title: Hypoxic ischemia and proteasome dysfunction alter tau isoform ratio by inhibiting exon 10 splicing.
Journal: Journal of neurochemistry 20100701
Title: Effects of Arkadia on airway remodeling through enhancing TGF-beta signaling in allergic rats.
Journal: Laboratory investigation; a journal of technical methods and pathology 20100701
Title: Increased degradation of MYPT1 contributes to the development of tolerance to nitric oxide in porcine pulmonary artery.
Journal: American journal of physiology. Lung cellular and molecular physiology 20100701
Title: Differential effects of lactacystin on cytokine production in activated Jurkat cells and murine splenocytes.
Journal: Cytokine 20100701
Title: Myocardial ischemic preconditioning preserves postischemic function of the 26S proteasome through diminished oxidative damage to 19S regulatory particle subunits.
Journal: Circulation research 20100625
Title: Ongoing DNA synthesis in the rat cerebral cortex is regulated by a proteolytic pathway independent of the proteasome and calpains.
Journal: Investigational new drugs 20100601
Title: Detrimental effect of the proteasome inhibitor, bortezomib in bacterial superantigen- and lipopolysaccharide-induced systemic inflammation.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20100601
Title: The 20S proteasome splicing activity discovered by SpliceMet.
Journal: PLoS computational biology 20100601
Title: Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson's and Alzheimer's diseases as disease modifying agents.
Journal: Experimental neurobiology 20100601
Title: The role of local protein synthesis and degradation in axon regeneration.
Journal: Experimental neurology 20100501
Title: Proteasome inhibition induces hsp30 and hsp70 gene expression as well as the acquisition of thermotolerance in Xenopus laevis A6 cells.
Journal: Cell stress & chaperones 20100501
Title: Ubiquitin/proteasome-dependent down-regulation following clathrin-mediated internalization of histamine H1-receptors in Chinese hamster ovary cells.
Journal: Journal of neurochemistry 20100501
Title: Synergistic effect between proteasome and autophagosome in the clearance of polyubiquitinated TDP-43.
Journal: Journal of neuroscience research 20100301
Title: Intrastriatal transplantation of GDNF-engineered BMSCs and its neuroprotection in lactacystin-induced Parkinsonian rat model.
Journal: Neurochemical research 20100301
Title: The pattern of neuronal loss and survival may reflect differential expression of proteasome activators in Parkinson's disease.
Journal: Synapse (New York, N.Y.) 20100301
Title: High glucose and interleukin-1beta downregulate interleukin-1 type I receptor (IL-1RI) in retinal endothelial cells by enhancing its degradation by a lysosome-dependent mechanism.
Journal: Cytokine 20100301
Title: Effect of proteasome inhibitors with different chemical structures on the ubiquitin-proteasome system in vitro.
Journal: Veterinary pathology 20100301
Title: Abstracts of the 16th Annual Society on NeuroImmune Pharmacology (SNIP) Conference. April 13-17, 2010. Manhattan Beach, California, USA.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20100301
Title: Proteasome inhibitor lactacystin induces cholinergic degeneration.
Journal: The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20100301
Title: E3 ligase Nedd4 promotes axon branching by downregulating PTEN.
Journal: Neuron 20100211
Title: Genetic iron chelation protects against proteasome inhibition-induced dopamine neuron degeneration.
Journal: Neurobiology of disease 20100201
Title: Pathogenic mutations cause rapid degradation of lysosomal storage disease-related membrane protein CLN6.
Journal: Human mutation 20100201
Title: Hsp40 chaperones promote degradation of the HERG potassium channel.
Journal: The Journal of biological chemistry 20100129
Title: Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion.
Journal: Cardiovascular research 20100115
Title: Distinct regulation of insulin receptor substrate-1 and -2 by 90-kDa heat-shock protein in adrenal chromaffin cells.
Journal: Neurochemistry international 20100101
Title: The role of zinc in the modulation of neuronal proliferation and apoptosis.
Journal: Neurotoxicity research 20100101
Title: Prevention of intracellular degradation of I2020T mutant LRRK2 restores its protectivity against apoptosis.
Journal: Biochemical and biophysical research communications 20100101
Title: Translocation of lysosomal cathepsin D caused by oxidative stress or proteasome inhibition in primary cultured neurons and astrocytes.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Non-invasive evaluation of nigrostriatal neuropathology in a proteasome inhibitor rodent model of Parkinson's disease.
Journal: BMC neuroscience 20100101
Title: Copper downregulates neprilysin activity through modulation of neprilysin degradation.
Journal: Journal of Alzheimer's disease : JAD 20100101
Title: Activation of mutant enzyme function in vivo by proteasome inhibitors and treatments that induce Hsp70.
Journal: PLoS genetics 20100101
Title: Bortezomib.
Journal: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101
Title: The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation.
Journal: PLoS genetics 20100101
Title: TWEAK activates the non-canonical NFkappaB pathway in murine renal tubular cells: modulation of CCL21.
Journal: PloS one 20100101
Title: Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype.
Journal: BMC neuroscience 20100101
Title: BRCA1 as a Therapeutic Target in Sporadic Epithelial Ovarian Cancer.
Journal: Journal of oncology 20100101
Title: Role of STAT3 in in vitro transformation triggered by TRK oncogenes.
Journal: PloS one 20100101
Title: Degradation of postsynaptic scaffold GKAP and regulation of dendritic spine morphology by the TRIM3 ubiquitin ligase in rat hippocampal neurons.
Journal: PloS one 20100101
Title: Changes in Activity and Kinetic Properties of the Proteasome in Different Rat Organs during Development and Maturation.
Journal: Current gerontology and geriatrics research 20100101
Title: Role of the proteasome in excitotoxicity-induced cleavage of glutamic acid decarboxylase in cultured hippocampal neurons.
Journal: PloS one 20100101
Title: NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphoma.
Journal: Molecular cancer 20100101
Title: Cellular localization of the herpes simplex virus ICP0 protein dictates its ability to block IRF3-mediated innate immune responses.
Journal: PloS one 20100101
Title: Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells.
Journal: Molecular cancer 20100101
Title: Acute effects of the sigma-2 receptor agonist siramesine on lysosomal and extra-lysosomal proteolytic systems in lens epithelial cells.
Journal: Molecular vision 20100101
Title: Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents.
Journal: PloS one 20100101
Title: Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamides.
Journal: Marine drugs 20100101
Title: Lamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10.
Journal: PloS one 20100101
Title: Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors.
Journal: PloS one 20100101
Title: Anti-inflammatory treatment strategies for ischemia/reperfusion injury in transplantation.
Journal: Journal of inflammation (London, England) 20100101
Title: Quercetin targets cysteine string protein (CSPalpha) and impairs synaptic transmission.
Journal: PloS one 20100101
Title: Deletion analysis of BMI1 oncoprotein identifies its negative regulatory domain.
Journal: Molecular cancer 20100101
Title: Cross-talk between mitochondria and proteasome in Parkinson's disease pathogenesis.
Journal: Frontiers in aging neuroscience 20100101
Title: Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin.
Journal: BMC cell biology 20100101
Title: Proteomic characterization of an isolated fraction of synthetic proteasome inhibitor (PSI)-induced inclusions in PC12 cells might offer clues to aggresomes as a cellular defensive response against proteasome inhibition by PSI.
Journal: BMC neuroscience 20100101
Title: Characterization of the Brain 26S Proteasome and its Interacting Proteins.
Journal: Frontiers in molecular neuroscience 20100101
Title: Functional characterization of the protein C A267T mutation: evidence for impaired secretion due to defective intracellular transport.
Journal: BMC cell biology 20100101
Title: The WW-HECT protein Smurf2 interacts with the Docking Protein NEDD9/HEF1 for Aurora A activation.
Journal: Cell division 20100101
Title: The Enigma of Tripeptidyl-Peptidase II: Dual Roles in Housekeeping and Stress.
Journal: Journal of oncology 20100101
Title: Regulation of thromboxane receptor signaling at multiple levels by oxidative stress-induced stabilization, relocation and enhanced responsiveness.
Journal: PloS one 20100101
Title: BRCA1 Forms a Functional Complex with γ-H2AX as a Late Response to Genotoxic Stress.
Journal: Journal of nucleic acids 20100101
Title: Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport.
Journal: PloS one 20100101
Title: Monomerization of cytosolic mature smac attenuates interaction with IAPs and potentiation of caspase activation.
Journal: PloS one 20100101
Title: Treatment of breast cancer cells with proteasome inhibitor lactacystin increases the level of sensitivity to cell death induced by human immunodeficiency virus type 1.
Journal: Biological & pharmaceutical bulletin 20100101
Title: Cell type-specific neuroprotective activity of untranslocated prion protein.
Journal: PloS one 20100101
Title: The New Inhibitor of Monoamine Oxidase, M30, has a Neuroprotective Effect Against Dexamethasone-Induced Brain Cell Apoptosis.
Journal: Frontiers in neuroscience 20100101
Title: Protogenin, a new member of the immunoglobulin superfamily, is implicated in the development of the mouse lower first molar.
Journal: BMC developmental biology 20100101
Title: Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase.
Journal: Molecular cancer 20100101
Title: Proteasome inhibition and its therapeutic potential in multiple myeloma.
Journal: Biologics : targets & therapy 20100101
Title: Probing the anticancer mechanism of prospective herbal drug Withaferin A on mammals: a case study on human and bovine proteasomes.
Journal: BMC genomics 20100101
Title: A novel ER J-protein DNAJB12 accelerates ER-associated degradation of membrane proteins including CFTR.
Journal: Cell structure and function 20100101
Title: Acyl-protein thioesterase 2 catalyzes the deacylation of peripheral membrane-associated GAP-43.
Journal: PloS one 20100101
Title: Tocotrienols inhibit lipopolysaccharide-induced pro-inflammatory cytokines in macrophages of female mice.
Journal: Lipids in health and disease 20100101
Title: Optimal management of cancer anorexia-cachexia syndrome.
Journal: Cancer management and research 20100101
Title: The Relationship between Parkin and Protein Aggregation in Neurodegenerative Diseases.
Journal: Frontiers in psychiatry 20100101
Title: Proteasome inhibition increases tau accumulation independent of phosphorylation.
Journal: Neurobiology of aging 20091201
Title: Lysosome-dependent degradation of Notch3.
Journal: The international journal of biochemistry & cell biology 20091201
Title: Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition.
Journal: Aging cell 20091201
Title: Calcium-dependent plasma membrane repair requires m- or mu-calpain, but not calpain-3, the proteasome, or caspases.
Journal: Biochimica et biophysica acta 20091201
Title: The C-terminal region of serotonin transporter is important for its trafficking and glycosylation.
Journal: Journal of pharmacological sciences 20091201
Title: Involvement of puromycin-sensitive aminopeptidase in proteolysis of tau protein in cultured cells, and attenuated proteolysis of frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) mutant tau.
Journal: Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society 20091201
Title: [Classification and synthesis of ubiquitin-proteasome inhibitor].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20091201
Title: Induction of cross-priming of naive CD8+ T lymphocytes by recombinant bacillus Calmette-Guerin that secretes heat shock protein 70-major membrane protein-II fusion protein.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20091115
Title: Recessive hyperekplexia mutations of the glycine receptor alpha1 subunit affect cell surface integration and stability.
Journal: Journal of neurochemistry 20091101
Title: z-Leucinyl-leucinyl-norleucinal induces apoptosis of human glioblastoma tumor-initiating cells by proteasome inhibition and mitotic arrest response.
Journal: Molecular cancer research : MCR 20091101
Title: The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation.
Journal: PLoS pathogens 20091101
Title: The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression.
Journal: The Journal of biological chemistry 20091030
Title: The microtubule-targeting agent T0070907 induces proteasomal degradation of tubulin.
Journal: Biochemical and biophysical research communications 20091016
Title: Reactive oxygen species decrease cAMP response element binding protein expression in cardiomyocytes via a protein kinase D1-dependent mechanism that does not require Ser133 phosphorylation.
Journal: Molecular pharmacology 20091001
Title: Lactacystin requires reactive oxygen species and Bax redistribution to induce mitochondria-mediated cell death.
Journal: British journal of pharmacology 20091001
Title: Virus-Induced Chaperone-Enriched (VICE) domains function as nuclear protein quality control centers during HSV-1 infection.
Journal: PLoS pathogens 20091001
Title: Increased protein stability of FGF1 can compensate for its reduced affinity for heparin.
Journal: The Journal of biological chemistry 20090911
Title: Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling.
Journal: Journal of lipid research 20090901
Title: The glucose transporter 2 undergoes plasma membrane endocytosis and lysosomal degradation in a secretagogue-dependent manner.
Journal: Endocrinology 20090901
Title: Generation of dopamine neurons with improved cell survival and phenotype maintenance using a degradation-resistant nurr1 mutant.
Journal: Stem cells (Dayton, Ohio) 20090901
Title: Limiting transport steps and novel interactions of Connexin-43 along the secretory pathway.
Journal: Histochemistry and cell biology 20090901
Title: Role of protease inhibitors and acylation stimulating protein in the adipogenesis in 3T3-L1 cells.
Journal: Journal of veterinary science 20090901
Title: Nuclear factor kappaB inhibitors alleviate and the proteasome inhibitor PS-341 exacerbates radiation toxicity in zebrafish embryos.
Journal: Molecular cancer therapeutics 20090901
Title: [The role of interferon-gamma in prevention of hydrogen peroxide-induced oxidative injury to vascular endothelium].
Journal: Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20090901
Title: A cellular model to monitor proteasome dysfunction by alpha-synuclein.
Journal: Biochemistry 20090825
Title: [Dual effects of different concentrations of alpha-synuclein on the neurotoxicity of 6-hydroxydopamine in SH-SY5Y cells].
Journal: Sheng li xue bao : [Acta physiologica Sinica] 20090825
Title: Size limitation in translocation of fibroblast growth factor 1 fusion proteins across the endosomal membrane.
Journal: Biochemistry 20090804
Title: Nucleus accumbens neurons exhibit synaptic scaling that is occluded by repeated dopamine pre-exposure.
Journal: The European journal of neuroscience 20090801
Title: Rac1 inhibition negatively regulates transcriptional activity of the amyloid precursor protein gene.
Journal: Journal of neuroscience research 20090701
Title: An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity.
Journal: Autophagy 20090701
Title: Cyanide-induced death of dopaminergic cells is mediated by uncoupling protein-2 up-regulation and reduced Bcl-2 expression.
Journal: Toxicology and applied pharmacology 20090701
Title: The Parkinson disease-associated A30P mutation stabilizes alpha-synuclein against proteasomal degradation triggered by heme oxygenase-1 over-expression in human neuroblastoma cells.
Journal: Journal of neurochemistry 20090701
Title: Zinc protoporphyrin inhibition of lipopolysaccharide-, lipoteichoic acid-, and peptidoglycan-induced nitric oxide production through stimulating iNOS protein ubiquitination.
Journal: Toxicology and applied pharmacology 20090615
Title: F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage.
Journal: Nature 20090604
Title: Role for copper in the cellular and regulatory effects of heme-hemopexin.
Journal: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20090601
Title: Regulation of podoplanin/PA2.26 antigen expression in tumour cells. Involvement of calpain-mediated proteolysis.
Journal: The international journal of biochemistry & cell biology 20090601
Title: Nedd4 mediates ErbB4 JM-a/CYT-1 ICD ubiquitination and degradation in MDCK II cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090601
Title: Partial inhibition of proteasome activity enhances remyelination after cuprizone-induced demyelination.
Journal: Experimental neurology 20090601
Title: The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.
Journal: Nature cell biology 20090601
Title: Rapamycin down-regulates inducible nitric oxide synthase by inducing proteasomal degradation.
Journal: Biological & pharmaceutical bulletin 20090601
Title: Inhibition of lysosomal functions reduces proteasomal activity.
Journal: Neuroscience letters 20090529
Title: Enhanced antigen presentation and CTL activity by transduction of mature rather than immature dendritic cells with octaarginine-modified liposomes.
Journal: Journal of controlled release : official journal of the Controlled Release Society 20090521
Title: Targeting transcription factor NFkappaB: comparative analysis of proteasome and IKK inhibitors.
Journal: Cell cycle (Georgetown, Tex.) 20090515
Title: Nicastrin is dispensable for gamma-secretase protease activity in the presence of specific presenilin mutations.
Journal: The Journal of biological chemistry 20090508
Title: Three-dimensional structure-activity relationship study of belactosin A and its stereo- and regioisomers: development of potent proteasome inhibitors by a stereochemical diversity-oriented strategy.
Journal: Organic & biomolecular chemistry 20090507
Title: Lactacystin stimulates stellation of cultured rat cortical astrocytes.
Journal: Neurochemical research 20090501
Title: Characterization of proteasome inhibition on astrocytes cell cycle.
Journal: Journal of molecular neuroscience : MN 20090501
Title: Efficacy on anaplastic thyroid carcinoma of valproic acid alone or in combination with doxorubicin, a synthetic chenodeoxycholic acid derivative, or lactacystin.
Journal: International journal of oncology 20090501
Title: Targeting the proteasome pathway.
Journal: Expert opinion on therapeutic targets 20090501
Title: Disruption of the ubiquitin proteasome system following axonal stretch injury accelerates progression to secondary axotomy.
Journal: Journal of neurotrauma 20090501
Title: Regulation of the stability of cell surface E-cadherin by the proteasome.
Journal: Biochemical and biophysical research communications 20090417
Title: Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3.
Journal: The EMBO journal 20090408
Title: Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3T3-L1 adipocytes.
Journal: Endocrinology 20090401
Title: ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity.
Journal: Journal of molecular medicine (Berlin, Germany) 20090401
Title: Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1.
Journal: Cellular signalling 20090401
Title: Low molecular mass polypeptide-2 in human trophoblast: over-expression in hydatidiform moles and possible role in trophoblast cell invasion.
Journal: Placenta 20090401
Title: The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle.
Journal: PLoS pathogens 20090401
Title: A cell cycle timer for asymmetric spindle positioning.
Journal: PLoS biology 20090401
Title: Proteasome inhibition induces neurite outgrowth through posttranslational modification of TrkA receptor.
Journal: The international journal of biochemistry & cell biology 20090301
Title: Gene silencing of phogrin unveils its essential role in glucose-responsive pancreatic beta-cell growth.
Journal: Diabetes 20090301
Title: Peptides with dual binding specificity for HLA-A2 and HLA-E are encoded by alternatively spliced isoforms of the antioxidant enzyme peroxiredoxin 5.
Journal: International immunology 20090301
Title: TGFbeta prevents proteasomal degradation of the cyclin-dependent kinase inhibitor p27kip1 for cell cycle arrest.
Journal: Cell cycle (Georgetown, Tex.) 20090301
Title: Nigral degeneration with inclusion body formation and behavioral changes in rats after proteasomal inhibition.
Journal: Stereotactic and functional neurosurgery 20090301
Title: Protective effect against Parkinson's disease-related insults through the activation of XBP1.
Journal: Brain research 20090227
Title: Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates.
Journal: Molecular cell 20090227
Title: Diastereo- and enantioselective synthesis of beta-hydroxy-alpha-amino acids: application to the synthesis of a key intermediate for lactacystin.
Journal: The Journal of organic chemistry 20090220
Title: Inhibition of the 20S proteosome by a protein proteinase inhibitor: evidence that a natural serine proteinase inhibitor can inhibit a threonine proteinase.
Journal: Journal of biochemistry 20090201
Title: Proteasome regulation of dynamic transcription factor occupancy on the GnRH-stimulated luteinizing hormone beta-subunit promoter.
Journal: Molecular endocrinology (Baltimore, Md.) 20090201
Title: Rift Valley fever virus NSs protein promotes post-transcriptional downregulation of protein kinase PKR and inhibits eIF2alpha phosphorylation.
Journal: PLoS pathogens 20090201
Title: Post-translational modification of cyclin A1 is associated with staurosporine and TNFalpha induced apoptosis in leukemic cells.
Journal: Molecular and cellular biochemistry 20090101
Title: The host adherens junction molecule nectin-1 is degraded by chlamydial protease-like activity factor (CPAF) in Chlamydia trachomatis-infected genital epithelial cells.
Journal: Microbes and infection 20090101
Title: Autophagy contributes to degradation of Hirano bodies.
Journal: Autophagy 20090101
Title: Epac mediates PACAP-dependent long-term depression in the hippocampus.
Journal: The Journal of physiology 20090101
Title: In vitro activity of bortezomib in cultures of patient tumour cells--potential utility in haematological malignancies.
Journal: Medical oncology (Northwood, London, England) 20090101
Title: Antiretroviral-related adipocyte dysfunction and lipodystrophy in HIV-infected patients: Alteration of the PPARγ-dependent pathways.
Journal: PPAR research 20090101
Title: Synergistic apoptosis induction in leukemic cells by the phosphatase inhibitor salubrinal and proteasome inhibitors.
Journal: PloS one 20090101
Title: Post-translational inhibition of IP-10 secretion in IEC by probiotic bacteria: impact on chronic inflammation.
Journal: PloS one 20090101
Title: Post-translational regulation of Oct4 transcriptional activity.
Journal: PloS one 20090101
Title: Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma.
Journal: PloS one 20090101
Title: HIV aspartyl peptidase inhibitors interfere with cellular proliferation, ultrastructure and macrophage infection of Leishmania amazonensis.
Journal: PloS one 20090101
Title: The anti-apoptotic activity of BAG3 is restricted by caspases and the proteasome.
Journal: PloS one 20090101
Title: Regulation of ErbB2 receptor status by the proteasomal DUB POH1.
Journal: PloS one 20090101
Title: Helicobacter pylori induces cancer cell motility independent of the c-Met receptor.
Journal: Journal of carcinogenesis 20090101
Title: Proteasome-independent degradation of HIV-1 in naturally non-permissive human placental trophoblast cells.
Journal: Retrovirology 20090101
Title: The immunosuppressive properties of the HIV Vpr protein are linked to a single highly conserved residue, R90.
Journal: PloS one 20090101
Title: Regulation of LRRK2 stability by the E3 ubiquitin ligase CHIP.
Journal: PloS one 20090101
Title: Long-term potentiation in isolated dendritic spines.
Journal: PloS one 20090101
Title: Retinal pigment epithelial cells secrete neurotrophic factors and synthesize dopamine: possible contribution to therapeutic effects of RPE cell transplantation in Parkinson's disease.
Journal: Journal of translational medicine 20090101
Title: Mitogen-activated protein kinases and NFkappaB are involved in SP-A-enhanced responses of macrophages to mycobacteria.
Journal: Respiratory research 20090101
Title: Hypoxia-induced transcription of dopamine D3 and D4 receptors in human neuroblastoma and astrocytoma cells.
Journal: BMC neuroscience 20090101
Title: The cytotoxicity of gamma-secretase inhibitor I to breast cancer cells is mediated by proteasome inhibition, not by gamma-secretase inhibition.
Journal: Breast cancer research : BCR 20090101
Title: FoxM1 is a general target for proteasome inhibitors.
Journal: PloS one 20090101
Title: 50 Hz extremely low frequency electromagnetic fields enhance protein carbonyl groups content in cancer cells: effects on proteasomal systems.
Journal: Journal of biomedicine & biotechnology 20090101
Title: Immature and mature species of the human Prostacyclin Receptor are ubiquitinated and targeted to the 26S proteasomal or lysosomal degradation pathways, respectively.
Journal: Journal of molecular signaling 20090101
Title: Proteasomal degradation of beta-carotene metabolite--modified proteins.
Journal: BioFactors (Oxford, England) 20090101
Title: Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration.
Journal: PloS one 20090101
Title: Notch versus the proteasome: what is the target of gamma-secretase inhibitor-I?
Journal: Breast cancer research : BCR 20090101
Title: The C-terminal sequence of RhoB directs protein degradation through an endo-lysosomal pathway.
Journal: PloS one 20090101
Title: Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases.
Journal: PloS one 20090101
Title: CXCR4 expression heterogeneity in neuroblastoma cells due to ligand-independent regulation.
Journal: Molecular cancer 20090101
Title: Discovery of novel proteasome inhibitors using a high-content cell-based screening system.
Journal: PloS one 20090101
Title: Ziram causes dopaminergic cell damage by inhibiting E1 ligase of the proteasome.
Journal: The Journal of biological chemistry 20081212
Title: ER stress is the initial response to polyglutamine toxicity in PC12 cells.
Journal: Biochemical and biophysical research communications 20081212
Title: Structural basis for activation and inhibition of the secreted chlamydia protease CPAF.
Journal: Cell host & microbe 20081211
Title: Consequences of the DYT1 mutation on torsinA oligomerization and degradation.
Journal: Neuroscience 20081202
Title: Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation.
Journal: Journal of cellular and molecular medicine 20081201
Title: Proteomic analysis of Chlamydia pneumoniae-infected HL cells reveals extensive degradation of cytoskeletal proteins.
Journal: FEMS immunology and medical microbiology 20081201
Title: Enhanced killing of androgen-independent prostate cancer cells using inositol hexakisphosphate in combination with proteasome inhibitors.
Journal: British journal of cancer 20081104
Title: Induction of BAG2 protein during proteasome inhibitor-induced apoptosis in thyroid carcinoma cells.
Journal: British journal of pharmacology 20081101
Title: Study of the effects of proteasome inhibitors on ribosomal protein S19 (RPS19) mutants, identified in patients with Diamond-Blackfan anemia.
Journal: Haematologica 20081101
Title: Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity.
Journal: Cancer biology & therapy 20081101
Title: Urea-mediated cross-presentation of soluble Epstein-Barr virus BZLF1 protein.
Journal: PLoS pathogens 20081101
Title: S-nitrosylation of surfactant protein-D controls inflammatory function.
Journal: PLoS biology 20081101
Title: Proteasome affects the expression of aryl hydrocarbon receptor-regulated proteins.
Journal: Environmental toxicology and pharmacology 20081101
Title: The ubiquitin-proteasome system is necessary for long-term synaptic depression in Aplysia.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20081008
Title: Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement.
Journal: Neurobiology of disease 20081001
Title: The ubiquitin ligase Nedd4 mediates oxidized low-density lipoprotein-induced downregulation of insulin-like growth factor-1 receptor.
Journal: American journal of physiology. Heart and circulatory physiology 20081001
Title: c-Jun N-terminal kinase mediates lactacystin-induced dopamine neuron degeneration.
Journal: Journal of neuropathology and experimental neurology 20081001
Title: A combination of proteasome inhibitors and antibiotics prevents lethality in a septic shock model.
Journal: Innate immunity 20081001
Title: Signal peptide-dependent inhibition of MHC class I heavy chain translation by rhesus cytomegalovirus.
Journal: PLoS pathogens 20081001
Title: A new synthetic approach to (+)-lactacystin based on radical cyclisation of enantiopure alpha-ethynyl substituted serine derivatives to 4-methylenepyrrolidinones.
Journal: Organic & biomolecular chemistry 20080921
Title: Mitochondria and ubiquitin-proteasomal system interplay: relevance to Parkinson's disease.
Journal: Free radical biology & medicine 20080915
Title: Inhibition of proteasome activity blocks Trypanosoma cruzi growth and metacyclogenesis.
Journal: Parasitology research 20080901
Title: Insulin potentiates cytokine-induced VCAM-1 expression in human endothelial cells.
Journal: Biochimica et biophysica acta 20080901
Title: Regulation of myocardin factor protein stability by the LIM-only protein FHL2.
Journal: American journal of physiology. Heart and circulatory physiology 20080901
Title: Nuclear proteasomal degradation and cytoplasmic retention underlie early nuclear exclusion of transcription factor Max upon axon damage.
Journal: Experimental neurology 20080901
Title: Kaposi's sarcoma-associated herpesvirus K7 induces viral G protein-coupled receptor degradation and reduces its tumorigenicity.
Journal: PLoS pathogens 20080901
Title: Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte cocultures.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20080801
Title: Compounds that increase or mimic cyclic adenosine monophosphate enhance tristetraprolin degradation in lipopolysaccharide-treated murine j774 macrophages.
Journal: The Journal of pharmacology and experimental therapeutics 20080801
Title: Angiotensin II type 1 receptor signaling contributes to synaptophysin degradation and neuronal dysfunction in the diabetic retina.
Journal: Diabetes 20080801
Title: The COOH terminus of megalin regulates gene expression in opossum kidney proximal tubule cells.
Journal: American journal of physiology. Cell physiology 20080801
Title: Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation.
Journal: The Journal of biological chemistry 20080801
Title: Superoxide-mediated proteasomal degradation of Bcl-2 determines cell susceptibility to Cr(VI)-induced apoptosis.
Journal: Carcinogenesis 20080801
Title: Pramipexole has astrocyte-mediated neuroprotective effects against lactacystin toxicity.
Journal: Neuroscience letters 20080801
Title: Efficient MHC class I presentation by controlled intracellular trafficking of antigens in octaarginine-modified liposomes.
Journal: Molecular therapy : the journal of the American Society of Gene Therapy 20080801
Title: Formation of cholesterol-enriched structures by aberrant intracellular accumulation of ATP-binding cassette transporter A1.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20080801
Title: Nurr1 deficiency predisposes to lactacystin-induced dopaminergic neuron injury in vitro and in vivo.
Journal: Brain research 20080730
Title: Synthesis and proteasome inhibition of glycyrrhetinic acid derivatives.
Journal: Bioorganic & medicinal chemistry 20080715
Title: Ornithine decarboxylase interferes with macrophage-like differentiation and matrix metalloproteinase-9 expression by tumor necrosis factor alpha via NF-kappaB.
Journal: Leukemia research 20080701
Title: Dequalinium-induced cell death of yeast expressing alpha-synuclein-GFP fusion protein.
Journal: Neurochemical research 20080701
Title: TrkA receptor endolysosomal degradation is both ubiquitin and proteasome dependent.
Journal: Traffic (Copenhagen, Denmark) 20080701
Title: Multiple molecular pathways are involved in the neuroprotection of GDNF against proteasome inhibitor induced dopamine neuron degeneration in vivo.
Journal: Experimental biology and medicine (Maywood, N.J.) 20080701
Title: Proteasomal degradation of IRS-2, but not IRS-1 by calcineurin inhibition: attenuation of insulin-like growth factor-I-induced GSK-3beta and ERK pathways in adrenal chromaffin cells.
Journal: Neuropharmacology 20080701
Title: Proteasome inhibition suppresses essential immune functions of human CD4+ T cells.
Journal: Immunology 20080601
Title: The intracellular accumulation of polymeric neuroserpin explains the severity of the dementia FENIB.
Journal: Human molecular genetics 20080601
Title: Carbon monoxide decreases the level of iNOS protein and active dimer in IL-1beta-stimulated hepatocytes.
Journal: Nitric oxide : biology and chemistry 20080601
Title: Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease.
Journal: Journal of neurochemistry 20080601
Title: Rescue of mutant alpha-galactosidase A in the endoplasmic reticulum by 1-deoxygalactonojirimycin leads to trafficking to lysosomes.
Journal: Biochimica et biophysica acta 20080601
Title: NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33(ING1b).
Journal: EMBO reports 20080601
Title: Comparison of neuroprotective and neurorestorative capabilities of rasagiline and selegiline against lactacystin-induced nigrostriatal dopaminergic degeneration.
Journal: Journal of neurochemistry 20080601
Title: Proteasomal abnormalities in cortical Lewy body disease and the impact of proteasomal inhibition within cortical and cholinergic systems.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20080601
Title: Galphao/i-stimulated proteosomal degradation of RGS20: a mechanism for temporal integration of Gs and Gi pathways.
Journal: Cellular signalling 20080601
Title: Zinc adaptation and resistance to cadmium toxicity in mammalian cells: molecular insight by proteomic analysis.
Journal: Proteomics 20080601
Title: Natural compounds with proteasome inhibitory activity for cancer prevention and treatment.
Journal: Current protein & peptide science 20080601
Title: A green tea component suppresses posttranslational expression of basic fibroblast growth factor in colorectal cancer.
Journal: Gastroenterology 20080601
Title: Protein degradation, as with protein synthesis, is required during not only long-term spatial memory consolidation but also reconsolidation.
Journal: The European journal of neuroscience 20080601
Title: Water and ion channels: crucial in the initiation and progression of apoptosis in central nervous system?
Journal: Current neuropharmacology 20080601
Title: Regulation of Akt mRNA and protein levels by glycogen synthase kinase-3beta in adrenal chromaffin cells: effects of LiCl and SB216763.
Journal: European journal of pharmacology 20080531
Title: Proteasomes cleave at multiple sites within polyglutamine tracts: activation by PA28gamma(K188E).
Journal: The Journal of biological chemistry 20080509
Title: Promotion of neurite outgrowth by fibroblast growth factor receptor 1 overexpression and lysosomal inhibition of receptor degradation in pheochromocytoma cells and adult sensory neurons.
Journal: Neuroscience 20080502
Title: Proteasome inhibitors remarkably prevent translesion replication in cancer cells but not normal cells.
Journal: Cancer science 20080501
Title: Inhibition of plasminogen activator inhibitor-1 expression in vascular smooth muscle cells by protoporphyrins through a heme oxygenase-independent mechanism.
Journal: Molecular and cellular biochemistry 20080501
Title: Simultaneous presentation and cross-presentation of immune-stimulating complex-associated cognate antigen by antigen-specific B cells.
Journal: European journal of immunology 20080501
Title: Practical synthesis of a key intermediate for lactacystin from (R)-4-hydroxymethyl-2-phenyl-4,5-dihydrooxazol-4-ylmethyl acetate.
Journal: Chemical & pharmaceutical bulletin 20080501
Title: Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction.
Journal: PLoS pathogens 20080501
Title: Human immunodeficiency virus type 1 gp120-mediated disruption of tight junction proteins by induction of proteasome-mediated degradation of zonula occludens-1 and -2 in human brain microvascular endothelial cells.
Journal: Journal of neurovirology 20080501
Title: Caffeine induces cell death via activation of apoptotic signal and inactivation of survival signal in human osteoblasts.
Journal: International journal of molecular sciences 20080501
Title: BV-2 stimulation by lactacystin results in a strong inflammatory reaction and apoptotic neuronal death in SH-SY5Y cells.
Journal: Brain research 20080418
Title: Agonist-specific down regulation of mu-opioid receptors: Different cellular pathways are activated by different opioid agonists.
Journal: Life sciences 20080409
Title: Steroidogenic activity of StAR requires contact with mitochondrial VDAC1 and phosphate carrier protein.
Journal: The Journal of biological chemistry 20080404
Title: Enantioselective total syntheses of omuralide, 7-epi-omuralide, and (+)-lactacystin.
Journal: The Journal of organic chemistry 20080321
Title: Unsaturated lipid peroxidation-derived aldehydes activate autophagy in vascular smooth-muscle cells.
Journal: The Biochemical journal 20080315
Title: Prevention of deoxycholate-induced gastric apoptosis by aspirin: roles of NF-kappaB and PKC signaling.
Journal: The Journal of surgical research 20080301
Title: Arkadia regulates TGF-beta signaling during renal tubular epithelial to mesenchymal cell transition.
Journal: Kidney international 20080301
Title: Proteasome inhibition: an early or late event in nitric oxide-induced neuronal death?
Journal: Nitric oxide : biology and chemistry 20080301
Title: Effect of an experimental proteasome inhibitor on the cytoskeleton, cytosolic protein turnover, and induction in the neuronal cells in vitro.
Journal: Neurotoxicology 20080301
Title: Mitogen-activated protein kinase kinase 4/c-Jun NH2-terminal kinase kinase 1 protein expression is subject to translational regulation in prostate cancer cell lines.
Journal: Molecular cancer research : MCR 20080301
Title: A 39 kDa fragment of endogenous ASK1 suggests specific cleavage not degradation by the proteasome.
Journal: IUBMB life 20080301
Title: Yessotoxin inhibits the complete degradation of E-cadherin.
Journal: Toxicology 20080227
Title: Proteasomal inhibition and apoptosis regulatory changes in human isolated lymphocytes: the synergistic role of dopamine.
Journal: Journal of cellular biochemistry 20080215
Title: Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response.
Journal: Aging cell 20080201
Title: Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway.
Journal: Traffic (Copenhagen, Denmark) 20080201
Title: Immunocytochemical analysis for intracellular dynamics of C1GalT associated with molecular chaperone, Cosmc.
Journal: Biochemical and biophysical research communications 20080201
Title: Protein quality control: the who's who, the where's and therapeutic escapes.
Journal: Histochemistry and cell biology 20080201
Title: Cyclic AMP-dependent proteolysis of GATA-6 expressed on the intracellular membrane.
Journal: Cell biology international 20080201
Title: Oxidative injury induces selective rather than global inhibition of proteasomal activity.
Journal: Journal of molecular and cellular cardiology 20080201
Title: LPS induces the TNF-alpha-mediated downregulation of rat liver aquaporin-8: role in sepsis-associated cholestasis.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20080201
Title: Sensitivity of tumor cells to proteasome inhibitors is associated with expression levels and composition of proteasome subunits.
Journal: Cancer 20080201
Title: Efficient total synthesis of novel bioactive microbial metabolites.
Journal: Accounts of chemical research 20080201
Title: Nitric oxide-dependent proteasomal degradation of cytochrome P450 2B proteins.
Journal: The Journal of biological chemistry 20080111
Title: Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells.
Journal: The EMBO journal 20080109
Title: Neonatal and adult microglia cross-present exogenous antigens.
Journal: Glia 20080101
Title: Constitutive activation of c-Met is correlated with c-Met overexpression and dependent on cell-matrix adhesion in lung adenocarcinoma cell lines.
Journal: Cancer science 20080101
Title: Oncostatin M induces growth arrest of skeletal muscle cells in G1 phase by regulating cyclin D1 protein level.
Journal: Cellular signalling 20080101
Title: Cross-presentation of NY-ESO-1 cytotoxic T lymphocyte epitope fused to human heat shock cognate protein 70 by dendritic cells.
Journal: Cancer science 20080101
Title: Metabolic and morphological alterations induced by proteolysis-inducing factor from Walker tumour-bearing rats in C2C12 myotubes.
Journal: BMC cancer 20080101
Title: Hsc70 focus formation at the periphery of HSV-1 transcription sites requires ICP27.
Journal: PloS one 20080101
Title: Alterations in the Notch4 pathway in cerebral endothelial cells by the HIV aspartyl protease inhibitor, nelfinavir.
Journal: BMC neuroscience 20080101
Title: Expression of K6W-ubiquitin in lens epithelial cells leads to upregulation of a broad spectrum of molecular chaperones.
Journal: Molecular vision 20080101
Title: Excessive islet NO generation in type 2 diabetic GK rats coincides with abnormal hormone secretion and is counteracted by GLP-1.
Journal: PloS one 20080101
Title: Marine actinomycetes: a new source of compounds against the human malaria parasite.
Journal: PloS one 20080101
Title: Complex molecular mechanisms cooperate to mediate histone deacetylase inhibitors anti-tumour activity in neuroblastoma cells.
Journal: Molecular cancer 20080101
Title: Ubiquitination is required for effective replication of coxsackievirus B3.
Journal: PloS one 20080101
Title: AIP4/Itch regulates Notch receptor degradation in the absence of ligand.
Journal: PloS one 20080101
Title: Supernatant from bifidobacterium differentially modulates transduction signaling pathways for biological functions of human dendritic cells.
Journal: PloS one 20080101
Title: Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon.
Journal: Malaria journal 20080101
Title: Changes in ocular aquaporin-4 (AQP4) expression following retinal injury.
Journal: Molecular vision 20080101
Title: Bifidobacterium strains suppress in vitro the pro-inflammatory milieu triggered by the large intestinal microbiota of coeliac patients.
Journal: Journal of inflammation (London, England) 20080101
Title: Targeting the UPS as therapy in multiple myeloma.
Journal: BMC biochemistry 20080101
Title: The UPS: a promising target for breast cancer treatment.
Journal: BMC biochemistry 20080101
Title: Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity.
Journal: Molecular brain 20080101
Title: Modulation of the NF-kappaB pathway by Bordetella pertussis filamentous hemagglutinin.
Journal: PloS one 20080101
Title: Differential role of beta-arrestin ubiquitination in agonist-promoted down-regulation of M1 vs M2 muscarinic acetylcholine receptors.
Journal: Journal of molecular signaling 20080101
Title: Reduction of infectious bursal disease virus replication in cultured cells by proteasome inhibitors.
Journal: Virus genes 20071201
Title: Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071201
Title: Endoplasmic reticulum-associated degradation of growth hormone receptor in Janus kinase 2-deficient cells.
Journal: Endocrinology 20071201
Title: PPARalpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages.
Journal: British journal of pharmacology 20071201
Title: Linkage of curcumin-induced cell cycle arrest and apoptosis by cyclin-dependent kinase inhibitor p21(/WAF1/CIP1).
Journal: Cell cycle (Georgetown, Tex.) 20071201
Title: NSAIDs enhance proteasomic degradation of survivin, a mechanism of gastric epithelial cell injury and apoptosis.
Journal: Biochemical pharmacology 20071115
Title: Parkinson's disease genetic mutations increase cell susceptibility to stress: mutant alpha-synuclein enhances H2O2- and Sin-1-induced cell death.
Journal: Neurobiology of aging 20071101
Title: 4-Hydroxy-2-nonenal increases superoxide anion radical in endothelial cells via stimulated GTP cyclohydrolase proteasomal degradation.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20071101
Title: Proteasome inhibitor lactacystin ablates liver injury induced by intestinal ischaemia-reperfusion.
Journal: Clinical and experimental pharmacology & physiology 20071101
Title: Dendritic cells process antigens encapsulated in a biodegradable polymer, poly(D,L-lactide-co-glycolide), via an alternate class I MHC processing pathway.
Journal: Archives of pharmacal research 20071101
Title: Human GCIP interacts with CT847, a novel Chlamydia trachomatis type III secretion substrate, and is degraded in a tissue-culture infection model.
Journal: Cellular microbiology 20071001
Title: Salinosporamide A (NPI-0052) potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through down-modulation of NF-kappaB regulated gene products.
Journal: Blood 20071001
Title: Cellular Zn2+ chelators cause 'dying-back' neurite degeneration associated with energy impairment.
Journal: Journal of neuroscience research 20071001
Title: The proteasome and intracellular redox status: implications for apoptotic regulation in lens epithelial cells.
Journal: Current eye research 20071001
Title: Treatment of PC12 cells with nerve growth factor induces proteasomal degradation of T-cadherin that requires tyrosine phosphorylation of its cadherin domain.
Journal: The Journal of biological chemistry 20070914
Title: The neuroprotective role of attractin in neurodegeneration.
Journal: Neurobiology of aging 20070901
Title: Cell cycle arrest and apoptosis induced by the coronavirus infectious bronchitis virus in the absence of p53.
Journal: Virology 20070901
Title: Splicing factor SF3b as a target of the antitumor natural product pladienolide.
Journal: Nature chemical biology 20070901
Title: Glial cell-derived neurotrophic factor protects against proteasome inhibition-induced dopamine neuron degeneration by suppression of endoplasmic reticulum stress and caspase-3 activation.
Journal: The journals of gerontology. Series A, Biological sciences and medical sciences 20070901
Title: Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein.
Journal: PLoS pathogens 20070901
Title: Downregulation of parkin damages antioxidant defenses and enhances proteasome inhibition-induced toxicity in PC12 cells.
Journal: Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20070901
Title: Future therapeutic treatment of COPD: struggle between oxidants and cytokines.
Journal: International journal of chronic obstructive pulmonary disease 20070901
Title: A directed approach for engineering conditional protein stability using biologically silent small molecules.
Journal: The Journal of biological chemistry 20070824
Title: Photobleaching reveals complex effects of inhibitors on transcribing RNA polymerase II in living cells.
Journal: Experimental cell research 20070815
Title: Differential endoplasmic reticulum stress signaling pathways mediated by iNOS.
Journal: Biochemical and biophysical research communications 20070803
Title: Proteasomes and RARS modulate AIMP1/EMAP II secretion in human cancer cell lines.
Journal: Journal of cellular physiology 20070801
Title: Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets.
Journal: American journal of physiology. Endocrinology and metabolism 20070801
Title: Beta-amyloid (25-35) enhances lipid metabolism and protein ubiquitination in cultured neurons.
Journal: Journal of neuroscience research 20070801
Title: Membrane cytosolic translocation of verotoxin A1 subunit in target cells.
Journal: Microbiology (Reading, England) 20070801
Title: Mechanisms of induction of endothelial cell E-selectin expression by smooth muscle cells and its inhibition by shear stress.
Journal: Blood 20070715
Title: Determinants of growth hormone receptor down-regulation.
Journal: Molecular endocrinology (Baltimore, Md.) 20070701
Title: Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070701
Title: Specific blockage of ligand-induced degradation of the Ah receptor by proteasome but not calpain inhibitors in cell culture lines from different species.
Journal: Biochemical pharmacology 20070630
Title: Requirement for the dynein light chain km23-1 in a Smad2-dependent transforming growth factor-beta signaling pathway.
Journal: The Journal of biological chemistry 20070629
Title: Novel tetra-acridine derivatives as dual inhibitors of topoisomerase II and the human proteasome.
Journal: Biochemical pharmacology 20070615
Title: Inhibiting proteasomal degradation of microsomal triglyceride transfer protein prevents CCl4-induced steatosis.
Journal: The Journal of biological chemistry 20070608
Title: Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2.
Journal: Carcinogenesis 20070601
Title: Localization of proteasomes and proteasomal proteolysis in the mammalian interphase cell nucleus by systematic application of immunocytochemistry.
Journal: Histochemistry and cell biology 20070601
Title: Protective role for nitric oxide during the endoplasmic reticulum stress response in pancreatic beta-cells.
Journal: American journal of physiology. Endocrinology and metabolism 20070601
Title: Endoplasmic reticulum stress-induced cell death mediated by the proteasome.
Journal: Cell death and differentiation 20070601
Title: Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
Journal: Nature chemical biology 20070601
Title: Low expression of cell-surface thromboxane A2 receptor beta-isoform through the negative regulation of its membrane traffic by proteasomes.
Journal: Prostaglandins & other lipid mediators 20070601
Title: Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system.
Journal: Cell 20070601
Title: Adrenoleukodystrophy: subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutations.
Journal: Journal of neurochemistry 20070601
Title: Proteasome inhibitor lactacystin disturbs the intracellular calcium homeostasis of dopamine neurons in ventral mesencephalic cultures.
Journal: Neurochemistry international 20070601
Title: A novel DNA damage response: rapid degradation of the p12 subunit of dna polymerase delta.
Journal: The Journal of biological chemistry 20070525
Title: Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells.
Journal: Journal of cellular physiology 20070501
Title: Degradation of nicastrin involves both proteasome and lysosome.
Journal: Journal of neurochemistry 20070501
Title: Smac-mediated sensitization of human B-lymphoma cells to staurosporine- and lactacystin-triggered apoptosis is apoptosome-dependent.
Journal: Leukemia 20070501
Title: Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins.
Journal: Current biology : CB 20070501
Title: Attenuation of muscle atrophy in a murine model of cachexia by inhibition of the dsRNA-dependent protein kinase.
Journal: British journal of cancer 20070423
Title: Post-induction, stimulus-specific regulation of tumor necrosis factor mRNA expression.
Journal: The Journal of biological chemistry 20070420
Title: Regulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexes.
Journal: The Journal of biological chemistry 20070420
Title: Effects of tau phosphorylation on proteasome activity.
Journal: FEBS letters 20070403
Title: Curcumin induces the degradation of cyclin E expression through ubiquitin-dependent pathway and up-regulates cyclin-dependent kinase inhibitors p21 and p27 in multiple human tumor cell lines.
Journal: Biochemical pharmacology 20070401
Title: Distinct roles of fibroblast growth factor receptor 1 and 2 in regulating cell survival and epithelial-mesenchymal transition.
Journal: Molecular endocrinology (Baltimore, Md.) 20070401
Title: Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment.
Journal: Human molecular genetics 20070401
Title: Phorbol esters induce intracellular accumulation of the anti-apoptotic protein PED/PEA-15 by preventing ubiquitinylation and proteasomal degradation.
Journal: The Journal of biological chemistry 20070323
Title: CD1d degradation in Chlamydia trachomatis-infected epithelial cells is the result of both cellular and chlamydial proteasomal activity.
Journal: The Journal of biological chemistry 20070309
Title: Regulation of STIM1, store-operated Ca2+ influx, and nitric oxide generation by retinoic acid in rat mesangial cells.
Journal: American journal of physiology. Renal physiology 20070301
Title: Posttranscriptional inhibition of interferon-gamma production by lead.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20070301
Title: Overexpression of lentivirus-mediated glial cell line-derived neurotrophic factor in bone marrow stromal cells and its neuroprotection for the PC12 cells damaged by lactacystin.
Journal: Neuroscience bulletin 20070301
Title: Activation of transcription factors by extracellular nucleotides in immune and related cell types.
Journal: Purinergic signalling 20070301
Title: Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease.
Journal: The Journal of biological chemistry 20070216
Title: Human endoplasmic reticulum mannosidase I is subject to regulated proteolysis.
Journal: The Journal of biological chemistry 20070216
Title: Ischemia promotes calpain-mediated degradation of p120-catenin in SH-SY5Y cells.
Journal: Biochemical and biophysical research communications 20070216
Title: Green tea polyphenol (-) -epigallocatechin-3-gallate promotes the rapid protein kinase C- and proteasome-mediated degradation of Bad: implications for neuroprotection.
Journal: Journal of neurochemistry 20070201
Title: Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.
Journal: Journal of natural products 20070201
Title: Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium.
Journal: Cancer research 20070201
Title: Total synthesis of lactacystin and salinosporamide A.
Journal: Chemistry, an Asian journal 20070108
Title: Proteasome dysfunction inhibits surfactant protein gene expression in lung epithelial cells: mechanism of inhibition of SP-B gene expression.
Journal: American journal of physiology. Lung cellular and molecular physiology 20070101
Title: Isolation and characterization of mammalian D-aspartyl endopeptidase.
Journal: Amino acids 20070101
Title: Pharmacological profiling of disulfiram using human tumor cell lines and human tumor cells from patients.
Journal: Biochemical pharmacology 20070101
Title: Inhibition of human preadipocyte proteasomal activity by HIV protease inhibitors or specific inhibitor lactacystin leads to a defect in adipogenesis, which involves matrix metalloproteinase-9.
Journal: The Journal of pharmacology and experimental therapeutics 20070101
Title: Proteasomal chymotrypsin-like peptidase activity is required for essential functions of human monocyte-derived dendritic cells.
Journal: Immunology 20070101
Title: Optimal determination of heart tissue 26S-proteasome activity requires maximal stimulating ATP concentrations.
Journal: Journal of molecular and cellular cardiology 20070101
Title: Proteolytic mechanisms underlying mitochondrial degradation in the ocular lens.
Journal: Investigative ophthalmology & visual science 20070101
Title: Are heat shock proteins therapeutic target for Parkinson's disease?
Journal: International journal of biological sciences 20070101
Title: Proteasome inhibitors in the clinical setting: benefits and strategies to overcome multiple myeloma resistance to proteasome inhibitors.
Journal: Drugs in R&D 20070101
Title: Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance.
Journal: Molecular cancer 20070101
Title: Proteasome activator enhances survival of Huntington's disease neuronal model cells.
Journal: PloS one 20070101
Title: Role of ubiquitination in IGF-1 receptor signaling and degradation.
Journal: PloS one 20070101
Title: The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention.
Journal: Molecular cancer 20070101
Title: Hook2 contributes to aggresome formation.
Journal: BMC cell biology 20070101
Title: Characterization of novel transforming growth factor-beta type I receptors found in malignant pleural effusion tumor cells.
Journal: BMC molecular biology 20070101
Title: The N-terminal 15-48 region of cyclin kinase inhibitor p21 is a determinant of basal expression.
Journal: Cancer genomics & proteomics 20070101
Title: Evidence for paternal leakage in hybrid periodical cicadas (Hemiptera: Magicicada spp.).
Journal: PloS one 20070101
Title: Antimalarial activity of the anticancer and proteasome inhibitor bortezomib and its analog ZL3B.
Journal: BMC clinical pharmacology 20070101
Title: The possible role of the ubiquitin proteasome system in the development of atherosclerosis in diabetes.
Journal: Cardiovascular diabetology 20070101
Title: Role of the ubiquitin proteasome system in Parkinson's disease.
Journal: BMC biochemistry 20070101
Title: The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias.
Journal: BMC biochemistry 20070101
Title: Role of proteasomes in disease.
Journal: BMC biochemistry 20070101
Title: Cells of the synovium in rheumatoid arthritis. Synovial fibroblasts.
Journal: Arthritis research & therapy 20070101
Title: Sustained stress response after oxidative stress in trabecular meshwork cells.
Journal: Molecular vision 20070101
Title: The proteasome inhibitor lactacystin attenuates growth and migration of vascular smooth muscle cells and limits the response to arterial injury.
Journal: Experimental and clinical cardiology 20070101
Title: Need for tripeptidyl-peptidase II in major histocompatibility complex class I viral antigen processing when proteasomes are detrimental.
Journal: The Journal of biological chemistry 20061229
Title: The ubiquitin ligase itch is auto-ubiquitylated in vivo and in vitro but is protected from degradation by interacting with the deubiquitylating enzyme FAM/USP9X.
Journal: The Journal of biological chemistry 20061215
Title: Effect of proteasome inhibition on toxicity and CYP3A23 induction in cultured rat hepatocytes: comparison with arsenite.
Journal: Toxicology and applied pharmacology 20061215
Title: Gastrointestinal hormones cause rapid c-Met receptor down-regulation by a novel mechanism involving clathrin-mediated endocytosis and a lysosome-dependent mechanism.
Journal: The Journal of biological chemistry 20061208
Title: Comparison of the neurotoxic effects of proteasomal inhibitors in primary mesencephalic cultures.
Journal: Experimental neurology 20061201
Title: Ubiquitin-proteasome pathway mediates degradation of APH-1.
Journal: Journal of neurochemistry 20061201
Title: Regulation of catechol-O-methyltransferase expression in human myometrial cells.
Journal: Obstetrics and gynecology 20061201
Title: The proteasome as a potential target for novel anticancer drugs and chemosensitizers.
Journal: Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20061201
Title: The internalization and degradation of human copper transporter 1 following cisplatin exposure.
Journal: Cancer research 20061115
Title: Lactacystin inhibits 3T3-L1 adipocyte differentiation through induction of CHOP-10 expression.
Journal: Biochemical and biophysical research communications 20061110
Title: Lactacystin decreases amyloid-beta peptide production by inhibiting beta-secretase activity.
Journal: Journal of neuroscience research 20061101
Title: Proteasome inhibition attenuates lung injury induced by intestinal ischemia reperfusion in rats.
Journal: Life sciences 20061026
Title: A novel proteasome inhibitor NPI-0052 as an anticancer therapy.
Journal: British journal of cancer 20061023
Title: Differential effects of NF-kappaB on apoptosis induced by DNA-damaging agents: the type of DNA damage determines the final outcome.
Journal: Oncogene 20061012
Title: OPG/membranous--RANKL complex is internalized via the clathrin pathway before a lysosomal and a proteasomal degradation.
Journal: Bone 20061001
Title: Constitutive activity of glycogen synthase kinase-3beta: positive regulation of steady-state levels of insulin receptor substrates-1 and -2 in adrenal chromaffin cells.
Journal: Brain research 20060919
Title: Codon optimized expression of HPV 16 E6 renders target cells susceptible to E6-specific CTL recognition.
Journal: Immunology letters 20060915
Title: PTEN is recruited to specific microdomains of the plasma membrane during lactacystin-induced neuronal apoptosis.
Journal: Neuroscience letters 20060911
Title: Photic regulation of arylalkylamine N-acetyltransferase binding to 14-3-3 proteins in retinal photoreceptor cells.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060906
Title: Release of iron from ferritin requires lysosomal activity.
Journal: American journal of physiology. Cell physiology 20060901
Title: A targeted protease substrate for a quantitative determination of protease activities in the endolysosomal pathway.
Journal: Chembiochem : a European journal of chemical biology 20060901
Title: Akt and Mammalian target of rapamycin regulate separate systems of proteolysis in renal tubular cells.
Journal: Journal of the American Society of Nephrology : JASN 20060901
Title: Cyclic AMP delays neutrophil apoptosis via stabilization of Mcl-1.
Journal: FEBS letters 20060821
Title: Degradation of insulin-like growth factor-I receptor occurs via ubiquitin-proteasome pathway in human lung cancer cells.
Journal: Journal of cellular physiology 20060801
Title: Cbl and Akt regulate CXCL8-induced and CXCR1- and CXCR2-mediated chemotaxis.
Journal: International immunology 20060801
Title: Role of heat shock response and Hsp27 in mutant SOD1-dependent cell death.
Journal: Experimental neurology 20060801
Title: The antiapoptotic effect of heme oxygenase-1 in endothelial cells involves the degradation of p38 alpha MAPK isoform.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060801
Title: Prediction of the mechanism of action of omuralide (clasto-lactacystin beta-lactone) on human cathepsin A based on a structural model of the yeast proteasome beta5/PRE2-subunit/omuralide complex.
Journal: Biochimica et biophysica acta 20060801
Title: Overlapping functions of argonaute proteins in patterning and morphogenesis of Drosophila embryos.
Journal: PLoS genetics 20060801
Title: Lysophosphatidic acid stimulates PC-3 prostate cancer cell Matrigel invasion through activation of RhoA and NF-kappaB activity.
Journal: Molecular carcinogenesis 20060701
Title: Regulation of proteolysis by cytokines in the human intestinal epithelial cell line HCT-8: role of IFNgamma.
Journal: Biochimie 20060701
Title: Secreted proteins from Mycobacterium tuberculosis gain access to the cytosolic MHC class-I antigen-processing pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20060701
Title: Cellular stability of Rho-GTPases glucosylated by Clostridium difficile toxin B.
Journal: FEBS letters 20060612
Title: Accumulation of the pro-apoptotic factor Bak is controlled by antagonist factor Mcl-1 availability.
Journal: Apoptosis : an international journal on programmed cell death 20060601
Title: Ceramides reduce CD36 cell surface expression and oxidised LDL uptake by monocytes and macrophages.
Journal: Archives of biochemistry and biophysics 20060601
Title: Proteasome-mediated regulation of CpG DNA- and peptidoglycan-induced cytokines, inflammatory genes, and mitogen-activated protein kinase activation.
Journal: Shock (Augusta, Ga.) 20060601
Title: Involvement of the paxillin pathway in JB6 Cl41 cell transformation.
Journal: Cancer research 20060601
Title: PU.1 is degraded in differentiation of erythrocytes through a proteasome-dependent pathway.
Journal: DNA and cell biology 20060601
Title: Alpha,beta-unsaturated beta-silyl imide substrates for catalytic, enantioselective conjugate additions: a total synthesis of (+)-lactacystin and the discovery of a new proteasome inhibitor.
Journal: Journal of the American Chemical Society 20060531
Title: Induction of protein degradation in skeletal muscle by a phorbol ester involves upregulation of the ubiquitin-proteasome proteolytic pathway.
Journal: Life sciences 20060515
Title: Proteasomal inhibition hypersensitizes differentiated neuroblastoma cells to oxidative damage.
Journal: Neuroscience letters 20060515
Title: Protective role of heat shock and heat shock protein 70 in lactacystin-induced cell death both in the rat substantia nigra and PC12 cells.
Journal: Brain research 20060504
Title: Activation of NFkappaB and Ub-proteasome pathway during apoptosis induced by a serum factor is mediated through the upregulation of the 26S proteasome subunits.
Journal: Apoptosis : an international journal on programmed cell death 20060501
Title: Lactacystin exhibits potent anti-tumor activity in an animal model of malignant glioma when administered via controlled-release polymers.
Journal: Journal of neuro-oncology 20060501
Title: The involvement of glycogen synthase kinase-3 and protein phosphatase-2A in lactacystin-induced tau accumulation.
Journal: FEBS letters 20060501
Title: Role of the proteasome in TGF-beta signaling in lens epithelial cells.
Journal: Investigative ophthalmology & visual science 20060501
Title: Evidence for a role of the ubiquitin-proteasome pathway in pancreatic islets.
Journal: Diabetes 20060501
Title: Key inflammatory signaling pathways are regulated by the proteasome.
Journal: Shock (Augusta, Ga.) 20060501
Title: Ubiquitin-dependent degradation of p53 protein despite phosphorylation at its N terminus by acetaminophen.
Journal: The Journal of pharmacology and experimental therapeutics 20060401
Title: Catabolism of endogenous and overexpressed APH1a and PEN2: evidence for artifactual involvement of the proteasome in the degradation of overexpressed proteins.
Journal: The Biochemical journal 20060301
Title: Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Title: Characterization of a neural-specific splicing form of the human neuregulin 3 gene involved in oligodendrocyte survival.
Journal: Journal of cell science 20060301
Title: Constitutively expressed catalytic proteasomal subunits are up-regulated during neuronal differentiation and required for axon initiation, elongation and maintenance.
Journal: Journal of neurochemistry 20060301
Title: The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis.
Journal: The Journal of biological chemistry 20060224
Title: Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis.
Journal: Experimental cell research 20060215
Title: Catalytic asymmetric total synthesis of (+)-lactacystin.
Journal: The Journal of organic chemistry 20060203
Title: Beta-adrenergic receptor trafficking by exercise in rat adipocytes: roles of G-protein-coupled receptor kinase-2, beta-arrestin-2, and the ubiquitin-proteasome pathway.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060201
Title: Heat shock protein 90 is an essential molecular chaperone for nuclear transport of glucocorticoid receptor beta.
Journal: Investigative ophthalmology & visual science 20060201
Title: Regulation of survivin by ErbB2 signaling: therapeutic implications for ErbB2-overexpressing breast cancers.
Journal: Cancer research 20060201
Title: E6AP and calmodulin reciprocally regulate estrogen receptor stability.
Journal: The Journal of biological chemistry 20060127
Title: Neurotrophic factors increase tumor necrosis factor-alpha-induced nuclear translocation of NF-kappaB in rat PC12 cells.
Journal: Neuroscience letters 20060116
Title: NF-kappaB activation is required for cisplatin-induced apoptosis in head and neck squamous carcinoma cells.
Journal: FEBS letters 20060109
Title: Posttranscriptional control of aquaporin-2 abundance by vasopressin in renal collecting duct principal cells.
Journal: American journal of physiology. Renal physiology 20060101
Title: Oxidative stress response results in increased p21WAF1/CIP1 degradation in cystic fibrosis lung epithelial cells.
Journal: Free radical biology & medicine 20060101
Title: Proteasome mediates removal of proteins oxidized during myocardial ischemia.
Journal: Free radical biology & medicine 20060101
Title: Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way.
Journal: Journal of cell science 20060101
Title: Selective relocalization and proteasomal downregulation of PKCalpha induced by platelet-activating factor in retinal pigment epithelium.
Journal: Investigative ophthalmology & visual science 20060101
Title: Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells.
Journal: Molecular cancer 20060101
Title: A single point mutation in the low-density lipoprotein receptor switches the degradation of its mature protein from the proteasome to the lysosome.
Journal: The international journal of biochemistry & cell biology 20060101
Title: 3-phosphoinositide-dependent protein kinase-1 (PDK1) promotes invasion and activation of matrix metalloproteinases.
Journal: BMC cancer 20060101
Title: Cyclooxygenase expression is not required for release of arachidonic acid from cells by some nonsteroidal anti-inflammatory drugs and cancer preventive agents.
Journal: BMC pharmacology 20060101
Title: Activation and degradation of protein C by primary rabbit pleural mesothelial cells.
Journal: Lung 20060101
Title: Porcine congenital splayleg is characterised by muscle fibre atrophy associated with relative rise in MAFbx and fall in P311 expression.
Journal: BMC veterinary research 20060101
Title: Phenotypical characteristics, biochemical pathways, molecular targets and putative role of nitric oxide-mediated programmed cell death in Leishmania.
Journal: Parasitology 20060101
Title: Silvestrol regulates G2/M checkpoint genes independent of p53 activity.
Journal: Anticancer research 20060101
Title: Serine phosphorylation regulates paxillin turnover during cell migration.
Journal: Cell communication and signaling : CCS 20060101
Title: Detection of a proteasome in Pneumocystis carinii and its modulation by specific proteasome inhibitors.
Journal: The Journal of eukaryotic microbiology 20060101
Title: Copper regulated synthesis, secretion and degradation of ceruloplasmin in a mouse immortalized hepatocytic cell line.
Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20051231
Title: Regulation of cytochrome P450 2E1 by heat shock protein 90-dependent stabilization and CHIP-dependent proteasomal degradation.
Journal: Biochemistry 20051213
Title: Regulation of cellular caveolin-1 protein expression in murine macrophages by microbial products.
Journal: Infection and immunity 20051201
Title: Combination of proteasomal inhibitors lactacystin and MG132 induced synergistic apoptosis in prostate cancer cells.
Journal: Neoplasia (New York, N.Y.) 20051201
Title: Disease-related prion protein forms aggresomes in neuronal cells leading to caspase activation and apoptosis.
Journal: The Journal of biological chemistry 20051118
Title: Proteasome inhibition induces selective motor neuron death in organotypic slice cultures.
Journal: Journal of neuroscience research 20051115
Title: Destabilization of Krüppel-like factor 4 protein in response to serum stimulation involves the ubiquitin-proteasome pathway.
Journal: Cancer research 20051115
Title: Resveratrol promotes clearance of Alzheimer's disease amyloid-beta peptides.
Journal: The Journal of biological chemistry 20051111
Title: Role of ubiquitin-proteasome degradation pathway in biogenesis efficiency of {beta}-cell ATP-sensitive potassium channels.
Journal: American journal of physiology. Cell physiology 20051101
Title: Induction and attenuation of neuronal apoptosis by proteasome inhibitors in murine cortical cell cultures.
Journal: Journal of neurochemistry 20051101
Title: UV-A light regulation of arylalkylamine N-acetyltransferase activity in the chick pineal gland: role of cAMP and proteasomal proteolysis.
Journal: Journal of pineal research 20051101
Title: Jak2 tyrosine kinase prevents angiotensin II-mediated inositol 1,4,5 trisphosphate receptor degradation.
Journal: Vascular pharmacology 20051101
Title: Anti-angiogenic and anti-tumor properties of proteasome inhibitors.
Journal: Current cancer drug targets 20051101
Title: A formal synthesis of (+)-lactacystin.
Journal: Chemical communications (Cambridge, England) 20051028
Title: Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults.
Journal: Journal of neuroscience research 20051015
Title: Oxidative stress augments the production of matrix metalloproteinase-1, cyclooxygenase-2, and prostaglandin E2 through enhancement of NF-kappa B activity in lipopolysaccharide-activated human primary monocytes.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20051015
Title: Expression of the ubiquitin-proteasome pathway and muscle loss in experimental cancer cachexia.
Journal: British journal of cancer 20051003
Title: Proteasome inhibition elicits a biphasic effect on neuronal apoptosis via differential regulation of pro-survival and pro-apoptotic transcription factors.
Journal: Molecular and cellular neurosciences 20051001
Title: Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system.
Journal: Biological chemistry 20051001
Title: Chemotherapy regimen GOLF induces apoptosis in colon cancer cells through multi-chaperone complex inactivation and increased Raf-1 ubiquitin-dependent degradation.
Journal: Cancer biology & therapy 20051001
Title: Accumulation of p53 in response to adenovirus early region 1A sensitizes human cells to tumor necrosis factor alpha-induced apoptosis.
Journal: Virology 20050930
Title: Apoptosis, necrosis and hypoxia inducible factor-1 in human head and neck squamous cell carcinoma cultures.
Journal: International journal of oncology 20050901
Title: Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblasts.
Journal: The American journal of pathology 20050901
Title: Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles.
Journal: British journal of cancer 20050822
Title: Angiotensin II directly induces muscle protein catabolism through the ubiquitin-proteasome proteolytic pathway and may play a role in cancer cachexia.
Journal: British journal of cancer 20050822
Title: Serotonin receptor activation leads to neurite outgrowth and neuronal survival.
Journal: Brain research. Molecular brain research 20050818
Title: Effect of statins on the proteasomal activity in mammalian endothelial and vascular smooth muscle cells.
Journal: Biochemical pharmacology 20050815
Title: [Proteasomal inhibitor lactacystin induces cell apoptosis and caspase 3 activation in PC12 cells].
Journal: Zhonghua yi xue za zhi 20050803
Title: Electromagnetic fields at mobile phone frequency induce apoptosis and inactivation of the multi-chaperone complex in human epidermoid cancer cells.
Journal: Journal of cellular physiology 20050801
Title: Long-term morphine treatment enhances proteasome-dependent degradation of G beta in human neuroblastoma SH-SY5Y cells: correlation with onset of adenylate cyclase sensitization.
Journal: Molecular pharmacology 20050801
Title: Appearance of virus-like particles in Tritrichomonas foetus after drug treatment.
Journal: Tissue & cell 20050801
Title: Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: a microarray analysis.
Journal: Journal of neurochemistry 20050801
Title: Apoptosis and the conformational change of Bax induced by proteasomal inhibition of PC12 cells are inhibited by bcl-xL and bcl-2.
Journal: Apoptosis : an international journal on programmed cell death 20050801
Title: Neuroprotection by iron chelator against proteasome inhibitor-induced nigral degeneration.
Journal: Biochemical and biophysical research communications 20050729
Title: Inefficient maturation of the rat luteinizing hormone receptor. A putative way to regulate receptor numbers at the cell surface.
Journal: The Journal of biological chemistry 20050715
Title: Neuroprotection of Parkin against apoptosis is independent of inclusion body formation.
Journal: Neuroreport 20050713
Title: Production of matrix metalloproteinase-9 by activated human monocytes involves a phosphatidylinositol-3 kinase/Akt/IKKalpha/NF-kappaB pathway.
Journal: Journal of leukocyte biology 20050701
Title: Selective induction of the tumor marker glutathione S-transferase P1 by proteasome inhibitors.
Journal: The Journal of biological chemistry 20050701
Title: Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride.
Journal: The Journal of biological chemistry 20050701
Title: Electrospray ionization mass spectrometry and ion mobility analysis of the 20S proteasome complex.
Journal: Journal of the American Society for Mass Spectrometry 20050701
Title: Rapid turnover of GATA-2 via ubiquitin-proteasome protein degradation pathway.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20050701
Title: Calcium-activated proteases are critical for refilling depleted vesicle stores in cultured sensory-motor synapses of Aplysia.
Journal: Learning & memory (Cold Spring Harbor, N.Y.) 20050701
Title: Brain microvessel endothelial cell responses to tumor necrosis factor-alpha involve a nuclear factor kappa B (NF-kappaB) signal transduction pathway.
Journal: Brain research 20050628
Title: The antiepidermal growth factor receptor monoclonal antibody cetuximab/C225 reduces hypoxia-inducible factor-1 alpha, leading to transcriptional inhibition of vascular endothelial growth factor expression.
Journal: Oncogene 20050623
Title: Epicatechin protects endothelial cells against oxidized LDL and maintains NO synthase.
Journal: Biochemical and biophysical research communications 20050617
Title: Mouse endothelial cells cross-present lymphocyte-derived antigen on class I MHC via a TAP1- and proteasome-dependent pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050615
Title: Phosphorylation of serine 188 protects RhoA from ubiquitin/proteasome-mediated degradation in vascular smooth muscle cells.
Journal: Circulation research 20050610
Title: Degradation of HMG-CoA reductase in rat liver is cholesterol and ubiquitin independent.
Journal: FEBS letters 20050606
Title: Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway.
Journal: American journal of physiology. Cell physiology 20050601
Title: Apoptotic cells deliver processed antigen to dendritic cells for cross-presentation.
Journal: PLoS biology 20050601
Title: Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate iHSP70, following proteasomal inhibition.
Journal: Journal of neurochemistry 20050601
Title: The effects of proteasome inhibitor lactacystin on mouse oocyte meiosis and first cleavage.
Journal: Science in China. Series C, Life sciences 20050601
Title: Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage.
Journal: The Journal of biological chemistry 20050513
Title: Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.
Journal: The Journal of biological chemistry 20050513
Title: Shear stress inhibits smooth muscle cell-induced inflammatory gene expression in endothelial cells: role of NF-kappaB.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050501
Title: Retrograde dopaminergic neuron degeneration following intrastriatal proteasome inhibition.
Journal: Neuroscience letters 20050501
Title: Ascorbate depletion: a critical step in nickel carcinogenesis?
Journal: Environmental health perspectives 20050501
Title: [Inhibiting expression of human telomerase reverse transcriptase promotes degradation of survivin protein].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20050501
Title: P2Y6 nucleotide receptors activate NF-kappaB and increase survival of osteoclasts.
Journal: The Journal of biological chemistry 20050429
Title: Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells.
Journal: The Journal of biological chemistry 20050422
Title: Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.
Journal: Blood 20050415
Title: Processing and presentation of HLA class I and II epitopes by dendritic cells after transfection with in vitro-transcribed MUC1 RNA.
Journal: Blood 20050415
Title: Microtubule-associated protein tau is a substrate of ATP/Mg(2+)-dependent proteasome protease system.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20050401
Title: Antitumorigenic effect of proteasome inhibitors on insulinoma cells.
Journal: Endocrinology 20050401
Title: Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells.
Journal: Molecular pharmacology 20050401
Title: Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells.
Journal: Experimental cell research 20050401
Title: Gamma-herpesvirus latency requires T cell evasion during episome maintenance.
Journal: PLoS biology 20050401
Title: Impairment of the ubiquitin-proteasome system by truncated cardiac myosin binding protein C mutants.
Journal: Cardiovascular research 20050401
Title: GLUT4 expression in 3T3-L1 adipocytes is repressed by proteasome inhibition, but not by inhibition of calpains.
Journal: Molecular and cellular endocrinology 20050331
Title: Cannabinoid receptor-induced neurite outgrowth is mediated by Rap1 activation through G(alpha)o/i-triggered proteasomal degradation of Rap1GAPII.
Journal: The Journal of biological chemistry 20050325
Title: Oxidative stress-mediated, post-translational loss of MafA protein as a contributing mechanism to loss of insulin gene expression in glucotoxic beta cells.
Journal: The Journal of biological chemistry 20050325
Title: Effects of DJ-1 mutations and polymorphisms on protein stability and subcellular localization.
Journal: Brain research. Molecular brain research 20050324
Title: Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation.
Journal: Journal of cell science 20050315
Title: Regulation of serum response factor-dependent gene expression by proteasome inhibitors.
Journal: Molecular pharmacology 20050301
Title: Characterization of signaling pathways leading to Fas expression induced by TNF-alpha: pivotal role of NF-kappaB.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301
Title: Glucosamine-induced endoplasmic reticulum stress promotes ApoB100 degradation: evidence for Grp78-mediated targeting to proteasomal degradation.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20050301
Title: Growth-associated protein-43 is degraded via the ubiquitin-proteasome system.
Journal: Journal of neuroscience research 20050301
Title: Trypanosoma cruzi histone H1 is phosphorylated in a typical cyclin dependent kinase site accordingly to the cell cycle.
Journal: Molecular and biochemical parasitology 20050301
Title: Effects of exogenous ubiquitin on cell division cycle mutants of Schizosaccharomyces pombe.
Journal: FEMS microbiology letters 20050301
Title: Does proteasome [corrected] inhibition decrease or accelerate toxin-induced dopaminergic neurodegeneration?
Journal: Journal of pharmacological sciences 20050301
Title: Nutritional regulation of proteases involved in fetal rat insulin secretion and islet cell proliferation.
Journal: The British journal of nutrition 20050301
Title: NF-kappaB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscle.
Journal: British journal of cancer 20050227
Title: Filamin A binding stabilizes nascent glycoprotein Ibalpha trafficking and thereby enhances its surface expression.
Journal: The Journal of biological chemistry 20050225
Title: Upregulation of clusterin/apolipoprotein J in lactacystin-treated SH-SY5Y cells.
Journal: Journal of neuroscience research 20050215
Title: Oxidized linoleic acid regulates expression and shedding of syndecan-4.
Journal: American journal of physiology. Cell physiology 20050201
Title: Role of Bcl-xL in paracetamol-induced tubular epithelial cell death.
Journal: Kidney international 20050201
Title: Proteasome inhibitors protect against degeneration of nigral dopaminergic neurons in hemiparkinsonian rats.
Journal: Journal of pharmacological sciences 20050201
Title: Proteasome inhibition protects HT22 neuronal cells from oxidative glutamate toxicity.
Journal: Journal of neurochemistry 20050201
Title: Proteasome or calpain inhibition does not alter cellular tau levels in neuroblastoma cells or primary neurons.
Journal: Journal of Alzheimer's disease : JAD 20050201
Title: Insulin receptor substrate-2 proteasomal degradation mediated by a mammalian target of rapamycin (mTOR)-induced negative feedback down-regulates protein kinase B-mediated signaling pathway in beta-cells.
Journal: The Journal of biological chemistry 20050121
Title: Proteasome-mediated effects on amyloid precursor protein processing at the gamma-secretase site.
Journal: The Biochemical journal 20050115
Title: Axonal protein synthesis and degradation are necessary for efficient growth cone regeneration.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050112
Title: Cellular ubiquitination and proteasomal functions positively modulate mammalian nucleotide excision repair.
Journal: Molecular carcinogenesis 20050101
Title: Alpha B-crystallin is a major component of glial cytoplasmic inclusions in multiple system atrophy.
Journal: Neurotoxicity research 20050101
Title: Kaposi's sarcoma associated herpes virus-encoded viral FLICE inhibitory protein activates transcription from HIV-1 Long Terminal Repeat via the classical NF-kappaB pathway and functionally cooperates with Tat.
Journal: Retrovirology 20050101
Title: The proteasome: a central regulator of inflammation and macrophage function.
Journal: Immunologic research 20050101
Title: Shear stress regulates gene expression in vascular endothelial cells in response to tumor necrosis factor-alpha: a study of the transcription profile with complementary DNA microarray.
Journal: Journal of biomedical science 20050101
Title: The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism.
Journal: BMC cancer 20050101
Title: In vitro and in vivo assays for osteoclast apoptosis.
Journal: Biological procedures online 20050101
Title: Anthracyclines, proteasome activity and multi-drug-resistance.
Journal: BMC cancer 20050101
Title: Cell-specific inhibition of paramyxovirus maturation by proteasome inhibitors.
Journal: Microbiology and immunology 20050101
Title: Constitutive degradation of IkappaBalpha in human T lymphocytes is mediated by calpain.
Journal: Immunity & ageing : I & A 20050101
Title: Ubiquitylation of neuronal nitric-oxide synthase by CHIP, a chaperone-dependent E3 ligase.
Journal: The Journal of biological chemistry 20041217
Title: The met receptor degradation pathway: requirement for Lys48-linked polyubiquitin independent of proteasome activity.
Journal: The Journal of biological chemistry 20041217
Title: Retinoic acid mediates degradation of IRS-1 by the ubiquitin-proteasome pathway, via a PKC-dependant mechanism.
Journal: Oncogene 20041209
Title: A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs.
Journal: The Biochemical journal 20041201
Title: 7-ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20041201
Title: Human CD8+ T cells recognize the 60-kDa cysteine-rich outer membrane protein from Chlamydia trachomatis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20041201
Title: Proteasome inhibitors suppress formation of polyglutamine-induced nuclear inclusions in cultured postmitotic neurons.
Journal: Journal of neurochemistry 20041201
Title: Loss of syk kinase during IgE-mediated stimulation of human basophils.
Journal: The Journal of allergy and clinical immunology 20041201
Title: BACE1 gene expression and protein degradation.
Journal: Annals of the New York Academy of Sciences 20041201
Title: Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach.
Journal: Biochimica et biophysica acta 20041129
Title: cAMP-dependent protein kinase regulates ubiquitin-proteasome-mediated degradation and subcellular localization of the nuclear receptor coactivator GRIP1.
Journal: The Journal of biological chemistry 20041119
Title: A novel gene family induced by acute inflammation in endothelial cells.
Journal: Gene 20041110
Title: alpha-synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons.
Journal: The Journal of biological chemistry 20041105
Title: Resistance of the human beta1-adrenergic receptor to agonist-induced ubiquitination: a mechanism for impaired receptor degradation.
Journal: The Journal of biological chemistry 20041105
Title: Coordination of oxidized protein hydrolase and the proteasome in the clearance of cytotoxic denatured proteins.
Journal: Biochemical and biophysical research communications 20041105
Title: Proteasomal interference prevents zona pellucida penetration and fertilization in mammals.
Journal: Biology of reproduction 20041101
Title: Protective effect of TAT-delivered alpha-synuclein: relevance of the C-terminal domain and involvement of HSP70.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041101
Title: Induction of proteasome expression in skeletal muscle is attenuated by inhibitors of NF-kappaB activation.
Journal: British journal of cancer 20041101
Title: Proteasomes act in the pre-mitochondrial signal transduction route towards roscovitine-induced apoptosis.
Journal: International journal of oncology 20041101
Title: Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism.
Journal: PLoS biology 20041101
Title: DJ-1 is a redox-dependent molecular chaperone that inhibits alpha-synuclein aggregate formation.
Journal: PLoS biology 20041101
Title: Probiotics inhibit nuclear factor-kappaB and induce heat shock proteins in colonic epithelial cells through proteasome inhibition.
Journal: Gastroenterology 20041101
Title: Effect of proteasome pathway on initiation of mouse labor induced by antiprogesterone.
Journal: American journal of reproductive immunology (New York, N.Y. : 1989) 20041101
Title: A concise route to (+)-lactacystin.
Journal: The Journal of organic chemistry 20041029
Title: Regulation of nicotinic receptor expression by the ubiquitin-proteasome system.
Journal: The EMBO journal 20041027
Title: Acute exercise alters Galphai2 protein expressions through the ubiquitin-proteasome proteolysis pathway in rat adipocytes.
Journal: Biochemical and biophysical research communications 20041022
Title: Degradation of BACE by the ubiquitin-proteasome pathway.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041001
Title: Identification of the protein disulfide isomerase family member PDIp in experimental Parkinson's disease and Lewy body pathology.
Journal: Brain research 20041001
Title: MKP-1 expression and stabilization and cGK Ialpha prevent diabetes- associated abnormalities in VSMC migration.
Journal: American journal of physiology. Cell physiology 20041001
Title: Inhibition of proteasome activity sensitizes dopamine neurons to protein alterations and oxidative stress.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20041001
Title: [BAY11-7082 and Lactacystein in CD154-induced NF-kappaB activation].
Journal: Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20041001
Title: Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells.
Journal: Toxicology and applied pharmacology 20040915
Title: Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040901
Title: Application of proteasomal inhibitors to mouse sympathetic neurons activates the intrinsic apoptotic pathway.
Journal: Journal of neurochemistry 20040901
Title: Mesangial cell Fas ligand: upregulation in human lupus nephritis and NF-kappaB-mediated expression in cultured human mesangial cells.
Journal: Clinical and experimental nephrology 20040901
Title: p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L).
Journal: Experimental cell research 20040815
Title: Lactacystin-induced apoptosis of cultured mouse cortical neurons is associated with accumulation of PTEN in the detergent-resistant membrane fraction.
Journal: Cellular and molecular life sciences : CMLS 20040801
Title: Nestin expression is lost in a neural stem cell line through a mechanism involving the proteasome and Notch signalling.
Journal: Brain research. Developmental brain research 20040719
Title: Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20040715
Title: The Leishmania chagasi proteasome: role in promastigotes growth and amastigotes survival within murine macrophages.
Journal: Acta tropica 20040701
Title: High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism.
Journal: The Journal of biological chemistry 20040625
Title: Proteolytic stress causes heat shock protein induction, tau ubiquitination, and the recruitment of ubiquitin to tau-positive aggregates in oligodendrocytes in culture.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040623
Title: Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.
Journal: The Journal of biological chemistry 20040611
Title: Transcriptional repression of E2F gene by proteasome inhibitors in human osteosarcoma cells.
Journal: Biochemical and biophysical research communications 20040611
Title: Degradation of the LDL receptor class 2 mutants is mediated by a proteasome-dependent pathway.
Journal: Journal of lipid research 20040601
Title: Protein kinase A activation of estrogen receptor alpha transcription does not require proteasome activity and protects the receptor from ligand-mediated degradation.
Journal: Endocrinology 20040601
Title: Efficient scavenger receptor-mediated uptake and cross-presentation of negatively charged soluble antigens by dendritic cells.
Journal: Immunology 20040601
Title: Distinct effects of the antiestrogen Faslodex on the stability of estrogen receptors-alpha and -beta in the breast cancer cell line MCF-7.
Journal: Journal of molecular endocrinology 20040601
Title: Endolysosomal processing of exogenous antigen into major histocompatibility complex class I-binding peptides.
Journal: Scandinavian journal of immunology 20040601
Title: Alpha-actinin-4-mediated FSGS: an inherited kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein.
Journal: PLoS biology 20040601
Title: CD8+ T cell cross-priming via transfer of proteasome substrates.
Journal: Science (New York, N.Y.) 20040528
Title: Role of protein kinase C and NF-kappaB in proteolysis-inducing factor-induced proteasome expression in C(2)C(12) myotubes.
Journal: British journal of cancer 20040504
Title: Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
Journal: Molecular cancer therapeutics 20040501
Title: Microbial serine carboxypeptidase inhibitors--comparative analysis of actions on homologous enzymes derived from man, yeast and wheat.
Journal: The Journal of antibiotics 20040501
Title: An efficient synthesis of lactacystin beta-lactone.
Journal: Angewandte Chemie (International ed. in English) 20040419
Title: Role of the NH2 terminus in the assembly and trafficking of the intermediate conductance Ca2+-activated K+ channel hIK1.
Journal: The Journal of biological chemistry 20040409
Title: AP-1-independent sensitization to oxidative stress-induced apoptosis by proteasome inhibitors.
Journal: Biochemical and biophysical research communications 20040402
Title: Influence of p53 and p21Waf1 expression on G2/M phase arrest of colorectal carcinoma HCT116 cells to proteasome inhibitors.
Journal: International journal of oncology 20040401
Title: Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts.
Journal: Journal of cellular biochemistry 20040401
Title: Alternative processing for MHC class I presentation by immature and CpG-activated dendritic cells.
Journal: European journal of immunology 20040401
Title: Effect of ajoene, a natural antitumor small molecule, on human 20S proteasome activity in vitro and in human leukemic HL60 cells.
Journal: Fundamental & clinical pharmacology 20040401
Title: Trastuzumab (Herceptin) enhances class I-restricted antigen presentation recognized by HER-2/neu-specific T cytotoxic lymphocytes.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040401
Title: Phthalocyanine tetrasulfonates affect the amyloid formation and cytotoxicity of alpha-synuclein.
Journal: Biochemistry 20040330
Title: The islet-specific glucose-6-phosphatase-related protein, implicated in diabetes, is a glycoprotein embedded in the endoplasmic reticulum membrane.
Journal: FEBS letters 20040326
Title: GSK3 beta-dependent phosphorylation of the alpha NAC coactivator regulates its nuclear translocation and proteasome-mediated degradation.
Journal: Biochemistry 20040316
Title: Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions.
Journal: The Journal of biological chemistry 20040312
Title: Degradation properties of polyglutamine-expanded human androgen receptor in transfected cells.
Journal: Neuroscience letters 20040311
Title: DJ-1 mutations are a rare cause of recessively inherited early onset parkinsonism mediated by loss of protein function.
Journal: Journal of medical genetics 20040301
Title: Effect of apolipoprotein A-I on ATP binding cassette transporter A1 degradation and cholesterol efflux in THP-1 macrophage-derived foam cells.
Journal: Acta biochimica et biophysica Sinica 20040301
Title: Long term proteasome inhibition does not preferentially afflict motor neurons in organotypical spinal cord cultures.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20040301
Title: Purification of the Arabidopsis 26 S proteasome: biochemical and molecular analyses revealed the presence of multiple isoforms.
Journal: The Journal of biological chemistry 20040220
Title: Molecular mechanisms regulating protein kinase Czeta turnover and cellular transformation.
Journal: The Biochemical journal 20040215
Title: Herceptin-geldanamycin immunoconjugates: pharmacokinetics, biodistribution, and enhanced antitumor activity.
Journal: Cancer research 20040215
Title: Mammalian D-aspartyl endopeptidase: a scavenger for noxious racemized proteins in aging.
Journal: Biochemical and biophysical research communications 20040213
Title: Sensitivity of proteasome to its inhibitors increases during cAMP-induced differentiation of neuroblastoma cells in culture and causes decreased viability.
Journal: Cancer letters 20040210
Title: Effect of ubiquitin-proteasome pathway on mouse blastocyst implantation and expression of matrix metalloproteinases-2 and -9.
Journal: Biology of reproduction 20040201
Title: Proteasome inhibitors induce inhibitory kappa B (I kappa B) kinase activation, I kappa B alpha degradation, and nuclear factor kappa B activation in HT-29 cells.
Journal: Molecular pharmacology 20040201
Title: Biochemical properties of the P42 protein encoded by RNA segment 6 of influenza C virus.
Journal: Archives of virology 20040201
Title: The inhibitory role of lactacystin and beta-lactacystin on T-cell activation and proliferation.
Journal: Acta biochimica et biophysica Sinica 20040201
Title: Implications of proteasome inhibition: an enhanced macrophage phenotype.
Journal: Cellular immunology 20040201
Title: [Effect of ubiquitin-proteasome pathway on TRAIL inducing apoptosis].
Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20040201
Title: Epidermal growth factor receptor activation differentially regulates claudin expression and enhances transepithelial resistance in Madin-Darby canine kidney cells.
Journal: The Journal of biological chemistry 20040130
Title: A new structural class of proteasome inhibitors identified by microbial screening using yeast-based assay.
Journal: Biochemical pharmacology 20040115
Title: Both insulin resistance and diabetes in Psammomys obesus upregulate the hepatic machinery involved in intracellular VLDL assembly.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040101
Title: Interferon-gamma induces apoptosis of lens alphaTN4-1 cells and proteasome inhibition has an antiapoptotic effect.
Journal: Investigative ophthalmology & visual science 20040101
Title: A novel gene mutation in the 60s loop of human coagulation factor VII - inhibition of interdomain crosstalk.
Journal: Thrombosis and haemostasis 20040101
Title: Examination of the mechanism(s) involved in doxorubicin-mediated iron accumulation in ferritin: studies using metabolic inhibitors, protein synthesis inhibitors, and lysosomotropic agents.
Journal: Molecular pharmacology 20040101
Title: Degradation of pro-insulin-receptor proteins by proteasomes.
Journal: Archives of medical research 20040101
Title: Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro.
Journal: Breast cancer research : BCR 20040101
Title: Heparin cofactor II is more sensitive than antithrombin to secretory impairment arising from mutations introduced into its carboxy-terminal region.
Journal: Thrombosis research 20040101
Title: The Icelandic founder mutation BRCA2 999del5: analysis of expression.
Journal: Breast cancer research : BCR 20040101
Title: Post-translational generation of constitutively active cores from larger phosphatases in the malaria parasite, Plasmodium falciparum: implications for proteomics.
Journal: BMC molecular biology 20040101
Title: Proteasome inhibitors: their effects on arachidonic acid release from cells in culture and arachidonic acid metabolism in rat liver cells.
Journal: BMC pharmacology 20040101
Title: Tamoxifen and the Rafoxifene analog LY117018: their effects on arachidonic acid release from cells in culture and on prostaglandin I2 production by rat liver cells.
Journal: BMC cancer 20040101
Title: Oxidative stress, induced by 6-hydroxydopamine, reduces proteasome activities in PC12 cells: implications for the pathogenesis of Parkinson's disease.
Journal: Journal of molecular neuroscience : MN 20040101
Title: Lipopolysaccharide negatively modulates vitamin D action by down-regulating expression of vitamin D-induced VDR in human monocytic THP-1 cells.
Journal: Cellular immunology 20040101
Title: Proteasome inhibition arrests neurite outgrowth and causes 'dying-back' degeneration in primary culture.
Journal: Journal of neuroscience research 20031215
Title: The effects of post-translational processing on dystroglycan synthesis and trafficking.
Journal: FEBS letters 20031204
Title: The ubiquitin-vacuolar protein sorting system is selectively required during entry of influenza virus into host cells.
Journal: Traffic (Copenhagen, Denmark) 20031201
Title: MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation.
Journal: The EMBO journal 20031201
Title: Retrograde transport of toxins across the endoplasmic reticulum membrane.
Journal: Biochemical Society transactions 20031201
Title: Circadian rhythm and photic control of cAMP level in chick retinal cell cultures: a mechanism for coupling the circadian oscillator to the melatonin-synthesizing enzyme, arylalkylamine N-acetyltransferase, in photoreceptor cells.
Journal: Brain research 20031121
Title: The mechanism of alphaB-crystallin gene expression by proteasome inhibition.
Journal: Biochemical and biophysical research communications 20031107
Title: Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.
Journal: Cytokine 20031107
Title: Proteolysis of type I inositol 1,4,5-trisphosphate receptor in WB rat liver cells.
Journal: The Biochemical journal 20031101
Title: Inhibition of proteasome function leads to NF-kappaB-independent IL-8 expression in human hepatocytes.
Journal: Hepatology (Baltimore, Md.) 20031101
Title: Insulin inhibition of protein degradation in cells expressing wild-type and mutant insulin receptors.
Journal: Journal of endocrinological investigation 20031101
Title: Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression.
Journal: Neuron 20031030
Title: Cell cycle- and activation-dependent regulation of cyclosporin A-induced T cell apoptosis.
Journal: Biochemical and biophysical research communications 20031017
Title: Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-kappaB-dependent process.
Journal: Oncogene 20031016
Title: Involvement of the ubiquitin-proteasome pathway and molecular chaperones in oculopharyngeal muscular dystrophy.
Journal: Human molecular genetics 20031015
Title: Adenovirus E4-34kDa requires active proteasomes to promote late gene expression.
Journal: Virology 20031010
Title: The ubiquitin-like domain of Herp is involved in Herp degradation, but not necessary for its enhancement of amyloid beta-protein generation.
Journal: FEBS letters 20031009
Title: A proteasome inhibitor reduces concurrent, sequential, and long-term IL-1 beta- and TNF-alpha-induced ECAM expression and adhesion.
Journal: American journal of physiology. Cell physiology 20031001
Title: Parkin is recruited to the centrosome in response to inhibition of proteasomes.
Journal: Journal of cell science 20031001
Title: Fine structure and biochemical mechanisms underlying nigrostriatal inclusions and cell death after proteasome inhibition.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031001
Title: Increased expression of the ubiquitin-proteasome pathway in murine myotubes by proteolysis-inducing factor (PIF) is associated with activation of the transcription factor NF-kappaB.
Journal: British journal of cancer 20030915
Title: Ligand-induced lysosomal epidermal growth factor receptor (EGFR) degradation is preceded by proteasome-dependent EGFR de-ubiquitination.
Journal: The Journal of biological chemistry 20030912
Title: Copper modulates the degradation of copper chaperone for Cu,Zn superoxide dismutase by the 26 S proteosome.
Journal: The Journal of biological chemistry 20030912
Title: Requirement of the proteasome for the trimming of signal peptide-derived epitopes presented by the nonclassical major histocompatibility complex class I molecule HLA-E.
Journal: The Journal of biological chemistry 20030905
Title: Proteasome is required for class I-restricted presentation by Fcgamma receptor-mediated endocytosis in primary biliary cirrhosis.
Journal: Journal of autoimmunity 20030901
Title: Induction of protein catabolism in myotubes by 15(S)-hydroxyeicosatetraenoic acid through increased expression of the ubiquitin-proteasome pathway.
Journal: British journal of cancer 20030818
Title: Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and -competent breast tumor cells.
Journal: The Journal of biological chemistry 20030808
Title: CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: accumulation of poly-ubiquitinated Hsp90 client proteins.
Journal: The Journal of biological chemistry 20030801
Title: Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels.
Journal: The Journal of biological chemistry 20030801
Title: Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb.
Journal: Cell death and differentiation 20030801
Title: Preservation of caspase-3 subunits from degradation contributes to apoptosis evoked by lactacystin: any single lysine or lysine pair of the small subunit is sufficient for ubiquitination.
Journal: Molecular pharmacology 20030801
Title: The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030801
Title: Proteasome inhibition reduces coxsackievirus B3 replication in murine cardiomyocytes.
Journal: The American journal of pathology 20030801
Title: Oxidative-stress-induced T lymphocyte hyporesponsiveness is caused by structural modification rather than proteasomal degradation of crucial TCR signaling molecules.
Journal: European journal of immunology 20030801
Title: Evidence for proteasome dysfunction in cytotoxicity mediated by anti-Ras intracellular antibodies.
Journal: European journal of biochemistry 20030801
Title: Shiga toxin induces decreased expression of the anti-apoptotic protein Mcl-1 concomitant with the onset of endothelial apoptosis.
Journal: Microbial pathogenesis 20030801
Title: Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A.
Journal: Oncogene 20030731
Title: The intracellular domain of teneurin-2 has a nuclear function and represses zic-1-mediated transcription.
Journal: Journal of cell science 20030715
Title: Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I.
Journal: The Journal of biological chemistry 20030711
Title: Function and stability of human transcobalamin II: role of intramolecular disulfide bonds C98-C291 and C147-C187.
Journal: American journal of physiology. Cell physiology 20030701
Title: Troglitazone reduces heat shock protein 70 content in primary rat hepatocytes by a ubiquitin proteasome independent mechanism.
Journal: Pharmacological research 20030701
Title: Dendritic cell maturation enhances CD8+ T-cell responses to exogenous antigen via a proteasome-independent mechanism of major histocompatibility complex class I loading.
Journal: Immunology 20030701
Title: Imaging 26S proteasome activity and inhibition in living mice.
Journal: Nature medicine 20030701
Title: Inhibition of the proteasome induces cell cycle arrest and apoptosis in mantle cell lymphoma cells.
Journal: British journal of haematology 20030701
Title: Proteasome inhibitors induce growth inhibition and apoptosis in myeloma cell lines and in human bone marrow myeloma cells irrespective of chromosome 13 deletion.
Journal: Journal of cancer research and clinical oncology 20030701
Title: Proteasomal inhibition causes the formation of protein aggregates containing a wide range of proteins, including nitrated proteins.
Journal: Journal of neurochemistry 20030701
Title: Cold-induced apoptosis of rat liver endothelial cells: involvement of the proteasome.
Journal: Transplantation 20030627
Title: Suppression of cytochrome P450 3A protein levels by proteasome inhibitors.
Journal: The Journal of pharmacology and experimental therapeutics 20030601
Title: Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS.
Journal: Journal of neurochemistry 20030601
Title: Identification and functional characterization of a novel R621C mutation in the synphilin-1 gene in Parkinson's disease.
Journal: Human molecular genetics 20030601
Title: Lactacystin augments the sulindac-induced apoptosis in HT-29 cells.
Journal: Apoptosis : an international journal on programmed cell death 20030601
Title: Inhibition of the proteasome by lactacystin enhances oligodendroglial cell differentiation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030601
Title: Myogenic differentiation of Drosophila Schneider cells by DNA double-strand break-inducing drugs.
Journal: Differentiation; research in biological diversity 20030601
Title: Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBPalpha) through a glycogen synthase kinase 3 (GSK3)-independent pathway involving direct inhibition of proteasomal activity.
Journal: The Journal of biological chemistry 20030530
Title: Tumor necrosis factor-alpha-induced targeted proteolysis of cystathionine beta-synthase modulates redox homeostasis.
Journal: The Journal of biological chemistry 20030509
Title: Proteasome inhibitors induce intracellular protein aggregation and cell death by an oxygen-dependent mechanism.
Journal: FEBS letters 20030508
Title: Quantity and quality control of gastric proton pump in the endoplasmic reticulum by ubiquitin/proteasome system.
Journal: Biochemistry 20030506
Title: Targeted degradation of ENaC in response to PKC activation of the ERK1/2 cascade.
Journal: American journal of physiology. Renal physiology 20030501
Title: Early degradation of paternal mitochondria in domestic pig (Sus scrofa) is prevented by selective proteasomal inhibitors lactacystin and MG132.
Journal: Biology of reproduction 20030501
Title: Early mitochondrial hyperpolarization and intracellular alkalinization in lactacystin-induced apoptosis of retinal pigment epithelial cells.
Journal: The Journal of pharmacology and experimental therapeutics 20030501
Title: Assessment of proteasome activity in cell lysates and tissue homogenates using peptide substrates.
Journal: The international journal of biochemistry & cell biology 20030501
Title: Differential regulation of proteasome-dependent estrogen receptor alpha and beta turnover in cultured human uterine artery endothelial cells.
Journal: The Journal of clinical endocrinology and metabolism 20030501
Title: Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.
Journal: Oncogene 20030501
Title: IRS1 degradation and increased serine phosphorylation cannot predict the degree of metabolic insulin resistance induced by oxidative stress.
Journal: Diabetologia 20030501
Title: Human platelet 20S proteasome: inhibition of its chymotrypsin-like activity and identification of the proteasome activator PA28. A preliminary report.
Journal: Platelets 20030501
Title: SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells.
Journal: Oncogene 20030424
Title: p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells.
Journal: Oncogene 20030417
Title: Calpain is involved in the HIV replication from the latently infected OM10.1 cells.
Journal: Biochemical and biophysical research communications 20030411
Title: Sumoylation of Pdx1 is associated with its nuclear localization and insulin gene activation.
Journal: American journal of physiology. Endocrinology and metabolism 20030401
Title: Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors.
Journal: Molecular endocrinology (Baltimore, Md.) 20030401
Title: Relationship between beta-amyloid degradation and the 26S proteasome in neural cells.
Journal: Experimental neurology 20030401
Title: Inhibition of ubiquitin ligase Siah-1A by disabled-1.
Journal: Biochemical and biophysical research communications 20030321
Title: NF-kappa B is required for surface Ig-induced Fas resistance in B cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20030315
Title: The human herpes virus 8-encoded viral FLICE inhibitory protein protects against growth factor withdrawal-induced apoptosis via NF-kappa B activation.
Journal: Blood 20030301
Title: Synthetic chenodeoxycholic acid derivative HS-1200-induced apoptosis of p815 mastocytoma cells is augmented by co-treatment with lactacystin.
Journal: Anti-cancer drugs 20030301
Title: Cycling B-CLL cells are highly susceptible to inhibition of the proteasome: involvement of p27, early D-type cyclins, Bax, and caspase-dependent and -independent pathways.
Journal: Experimental hematology 20030301
Title: Regulation of sympathetic neuron and neuroblastoma cell death by XIAP and its association with proteasomes in neural cells.
Journal: Molecular and cellular neurosciences 20030301
Title: EDEM as an acceptor of terminally misfolded glycoproteins released from calnexin.
Journal: Science (New York, N.Y.) 20030227
Title: Nuclear export inhibitor leptomycin B induces the appearance of novel forms of human Mdm2 protein.
Journal: British journal of cancer 20030224
Title: Ubiquitination of tissue transglutaminase is modulated by interferon alpha in human lung cancer cells.
Journal: The Biochemical journal 20030215
Title: Synaptic Drosophila UNC-13 is regulated by antagonistic G-protein pathways via a proteasome-dependent degradation mechanism.
Journal: Journal of neurobiology 20030215
Title: Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030215
Title: Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome.
Journal: The Journal of biological chemistry 20030214
Title: Inhibition of hepatitis B virus replication by drug-induced depletion of nucleocapsids.
Journal: Science (New York, N.Y.) 20030207
Title: Short and versatile route to a key intermediate for lactacystin synthesis.
Journal: Organic letters 20030206
Title: C-terminal Hsp-interacting protein slows androgen receptor synthesis and reduces its rate of degradation.
Journal: Archives of biochemistry and biophysics 20030201
Title: Fusion with HDEL protects cell wall invertase from early degradation when N-glycosylation is inhibited.
Journal: Plant & cell physiology 20030201
Title: [Synthetic studies of microbial natural products from microorganisms].
Journal: The Japanese journal of antibiotics 20030201
Title: Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium.
Journal: The Journal of biological chemistry 20030124
Title: NF-kappaB inhibition impairs the radioresponse of hypoxic EMT-6 tumour cells through downregulation of inducible nitric oxide synthase.
Journal: British journal of cancer 20030113
Title: Heterodimerization of endothelin-converting enzyme-1 isoforms regulates the subcellular distribution of this metalloprotease.
Journal: The Journal of biological chemistry 20030103
Title: Multiple forms of estrogen receptor-alpha in cerebral blood vessels: regulation by estrogen.
Journal: American journal of physiology. Endocrinology and metabolism 20030101
Title: A major role for tapasin as a stabilizer of the TAP peptide transporter and consequences for MHC class I expression.
Journal: European journal of immunology 20030101
Title: Statins stimulate arachidonic acid release and prostaglandin I2 production in rat liver cells.
Journal: Lipids in health and disease 20030101
Title: Tamoxifen stimulates arachidonic acid release from rat liver cells by an estrogen receptor-independent, non-genomic mechanism.
Journal: BMC cancer 20030101
Title: Ubiquitinylation and proteasome-dependent degradation of the phosphoinositide-specific phospholipase C gamma 1 in A-431 cells.
Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections 20030101
Title: Differential apoptotic response to the proteasome inhibitor Bortezomib [VELCADE, PS-341] in Bax-deficient and p21-deficient colon cancer cells.
Journal: Cancer biology & therapy 20030101
Title: [Effect of EGF on ubiquitination and proteasome-dependent degradation of phospholipase C gamma1 in A431 cells].
Journal: Tsitologiia 20030101
Title: Ubiquitination-independent trafficking of G protein-coupled receptors to lysosomes.
Journal: The Journal of biological chemistry 20021227
Title: Nitric oxide induces neutral ceramidase degradation by the ubiquitin/proteasome complex in renal mesangial cell cultures.
Journal: FEBS letters 20021218
Title: Mutations at the P1' position of Notch1 decrease intracellular domain stability rather than cleavage by gamma-secretase.
Journal: Biochemical and biophysical research communications 20021213
Title: Nuclear phosphatases and the proteasome in suppression of STAT1 activity in hepatocytes.
Journal: Biochemical and biophysical research communications 20021213
Title: Curcumin-induced suppression of cell proliferation correlates with down-regulation of cyclin D1 expression and CDK4-mediated retinoblastoma protein phosphorylation.
Journal: Oncogene 20021212
Title: Cleavage of p21waf1 by proteinase-3, a myeloid-specific serine protease, potentiates cell proliferation.
Journal: The Journal of biological chemistry 20021206
Title: Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis.
Journal: Journal of neurochemistry 20021201
Title: Structure-function analysis of the glucose-6-phosphate transporter deficient in glycogen storage disease type Ib.
Journal: Human molecular genetics 20021201
Title: Aggresome-related biogenesis of Lewy bodies.
Journal: The European journal of neuroscience 20021201
Title: c-Jun N-terminal kinase pathway mediates Lactacystin-induced cell death in a neuronal differentiated Neuro2a cell line.
Journal: Brain research. Molecular brain research 20021201
Title: Stimulation of melanoblast pigmentation by 8-methoxypsoralen:the involvement of microphthalmia-associated transcription factor, the protein kinase a signal pathway, and proteasome-mediated degradation.
Journal: The Journal of investigative dermatology 20021201
Title: CXCR4 heterogeneity in primary cells: possible role of ubiquitination.
Journal: Journal of leukocyte biology 20021201
Title: Nitric oxide induces degradation of the neutral ceramidase in rat renal mesangial cells and is counterregulated by protein kinase C.
Journal: The Journal of biological chemistry 20021129
Title: Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol.
Journal: Science (New York, N.Y.) 20021129
Title: ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.
Journal: The Journal of biological chemistry 20021108
Title: Proteinases of Trypanosoma cruzi: patential targets for the chemotherapy of Changas desease.
Journal: Current topics in medicinal chemistry 20021101
Title: Interleukin-3, but not granulocyte-macrophage colony-stimulating factor and interleukin-5, inhibits apoptosis of human basophils through phosphatidylinositol 3-kinase: requirement of NF-kappaB-dependent and -independent pathways.
Journal: Immunology 20021101
Title: Sustained activation of N-WASP through phosphorylation is essential for neurite extension.
Journal: Developmental cell 20021101
Title: Cytosolic and nuclear aggregation of the amyloid beta-peptide following its expression in the endoplasmic reticulum.
Journal: Histochemistry and cell biology 20021101
Title: Effects of proteasome inhibitor (lactacystin) and cysteine protease inhibitor (E-64-d) on processes of mitosis in Xenopus embryonic cells.
Journal: Zoological science 20021101
Title: Apoptosis in Schwann cell cultures is closely interrelated with the activity of the ubiquitin-proteasome proteolytic pathway.
Journal: Neurochemical research 20021101
Title: The life cycle of the steroidogenic acute regulatory (StAR) protein: from transcription through proteolysis.
Journal: Endocrine research 20021101
Title: Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop.
Journal: Science (New York, N.Y.) 20021025
Title: Proteasome inhibitors reconstitute the presentation of cytotoxic T-cell epitopes in Epstein-Barr virus-associated tumors.
Journal: International journal of cancer 20021020
Title: The final N-terminal trimming of a subaminoterminal proline-containing HLA class I-restricted antigenic peptide in the cytosol is mediated by two peptidases.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20021015
Title: Influence of phosphorylation of p35, an activator of cyclin-dependent kinase 5 (cdk5), on the proteolysis of p35.
Journal: Brain research. Molecular brain research 20021015
Title: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) up-regulates death receptor 5 (DR5) mediated by NFkappaB activation in epithelial derived cell lines.
Journal: Apoptosis : an international journal on programmed cell death 20021001
Title: Ligand-dependent and independent modulation of aryl hydrocarbon receptor localization, degradation, and gene regulation.
Journal: Molecular pharmacology 20021001
Title: Proteasomal degradation of tau protein.
Journal: Journal of neurochemistry 20021001
Title: Ezrin turnover and cell shape changes catalyzed by proteasome in oxidatively stressed cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Title: Cross-presentation of cell-associated antigens by CD8alpha+ dendritic cells is attributable to their ability to internalize dead cells.
Journal: Immunology 20021001
Title: Subcellular recruitment of fibrillarin to nucleoplasmic proteasomes: implications for processing of a nucleolar autoantigen.
Journal: Molecular biology of the cell 20021001
Title: Synphilin-1 degradation by the ubiquitin-proteasome pathway and effects on cell survival.
Journal: Journal of neurochemistry 20021001
Title: Accelerated degradation of mislocalized UDP-glucuronosyltransferase family 1 (UGT1) proteins in Gunn rat hepatocytes.
Journal: Archives of biochemistry and biophysics 20020915
Title: Proteasome inhibitors regulate tyrosine phosphorylation of IRS-1 and insulin signaling in adipocytes.
Journal: Biochemical and biophysical research communications 20020906
Title: Anticancer-drug-induced apoptotic cell death in leukemia cells is associated with proteolysis of beta-catenin.
Journal: Leukemia research 20020901
Title: Glucocorticoid-mediated attenuation of the hsp70 response in trout hepatocytes involves the proteasome.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020901
Title: The effects of lovastatin on proteasome activities in highly purified rabbit 20 S proteasome preparations and mouse MC3T3-E1 osteoblastic cells.
Journal: Metabolism: clinical and experimental 20020901
Title: Proteasome inhibitors induce apoptosis in growth hormone- and prolactin-secreting rat pituitary tumor cells.
Journal: The Journal of endocrinology 20020901
Title: Proteasome-dependent regulation of Syk tyrosine kinase levels in human basophils.
Journal: The Journal of allergy and clinical immunology 20020901
Title: Aberrant apoptosis in thyroid epithelial cells from goiter nodules.
Journal: The Journal of clinical endocrinology and metabolism 20020901
Title: Inhibition of hepatocyte apoB secretion by naringenin: enhanced rapid intracellular degradation independent of reduced microsomal cholesteryl esters.
Journal: Journal of lipid research 20020901
Title: Proteasome-dependent downregulation of p21(Waf1/Cip1) induced by reactive oxygen species.
Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20020901
Title: The DNA repair protein, O(6)-methylguanine-DNA methyltransferase is a proteolytic target for the E6 human papillomavirus oncoprotein.
Journal: Oncogene 20020829
Title: Proteasome inhibitors stimulate activator protein-1 pathway via reactive oxygen species production.
Journal: FEBS letters 20020828
Title: Induction and superinduction of 2,3,7,8-tetrachlorodibenzo-rho-dioxin-inducible poly(ADP-ribose) polymerase: role of the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator transcription activation domains and a labile transcription repressor.
Journal: Archives of biochemistry and biophysics 20020815
Title: Effect of wild-type or mutant Parkin on oxidative damage, nitric oxide, antioxidant defenses, and the proteasome.
Journal: The Journal of biological chemistry 20020809
Title: Proteasome inhibition causes nigral degeneration with inclusion bodies in rats.
Journal: Neuroreport 20020807
Title: The inhibition of microsomal triglyceride transfer protein activity in rat hepatoma cells promotes proteasomal and nonproteasomal degradation of apoprotein b100.
Journal: Biochemistry 20020806
Title: Evidence that inhibition of p44/42 mitogen-activated protein kinase signaling is a factor in proteasome inhibitor-mediated apoptosis.
Journal: The Journal of biological chemistry 20020802
Title: Effect of geranylgeranylaceton on cellular damage induced by proteasome inhibition in cultured spinal neurons.
Journal: Journal of neuroscience research 20020801
Title: Proteasome inhibitors stimulate interleukin-8 expression via Ras and apoptosis signal-regulating kinase-dependent extracellular signal-related kinase and c-Jun N-terminal kinase activation.
Journal: American journal of respiratory cell and molecular biology 20020801
Title: Proteasome inhibition leads to NF-kappaB-independent IL-8 transactivation in human endothelial cells through induction of AP-1.
Journal: European journal of immunology 20020801
Title: Expression of mutant alpha-synucleins enhances dopamine transporter-mediated MPP+ toxicity in vitro.
Journal: Neuroreport 20020719
Title: Increased proteolysis after single-dose exposure with hepatotoxins in HepG2 cells.
Journal: Free radical biology & medicine 20020715
Title: Aggresome formation in neuropathy models based on peripheral myelin protein 22 mutations.
Journal: Neurobiology of disease 20020701
Title: The effect of proteasome inhibitors on mammalian erythroid terminal differentiation.
Journal: Experimental hematology 20020701
Title: Troglitazone induces G1 arrest by p27(Kip1) induction that is mediated by inhibition of proteasome in human gastric cancer cells.
Journal: Japanese journal of cancer research : Gann 20020701
Title: Nuclear localization of N-terminal mutant huntingtin is cell cycle dependent.
Journal: The European journal of neuroscience 20020701
Title: Influence of peroxisome proliferator-activated receptor alpha agonists on the intracellular turnover and secretion of apolipoprotein (Apo) B-100 and ApoB-48.
Journal: The Journal of biological chemistry 20020621
Title: Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation.
Journal: The Journal of biological chemistry 20020621
Title: Mevastatin induces degeneration and decreases viability of cAMP-induced differentiated neuroblastoma cells in culture by inhibiting proteasome activity, and mevalonic acid lactone prevents these effects.
Journal: Journal of neuroscience research 20020601
Title: Proteasome inhibitors in the treatment of B-cell malignancies.
Journal: Clinical lymphoma 20020601
Title: Development of an in-vitro model system to investigate the mechanism of muscle protein catabolism induced by proteolysis-inducing factor.
Journal: British journal of cancer 20020520
Title: CXCR4/CCR5 down-modulation and chemotaxis are regulated by the proteasome pathway.
Journal: The Journal of biological chemistry 20020517
Title: Biosynthesis and secretion of parathyroid hormone are sensitive to proteasome inhibitors in dispersed bovine parathyroid cells.
Journal: The Journal of biological chemistry 20020517
Title: Ubiquitin/proteasome-dependent degradation of D-type cyclins is linked to tumor necrosis factor-induced cell cycle arrest.
Journal: The Journal of biological chemistry 20020510
Title: Diffusional mobility of the cystic fibrosis transmembrane conductance regulator mutant, delta F508-CFTR, in the endoplasmic reticulum measured by photobleaching of GFP-CFTR chimeras.
Journal: The Journal of biological chemistry 20020510
Title: An easily dissociated 26 S proteasome catalyzes an essential ubiquitin-mediated protein degradation pathway in Trypanosoma brucei.
Journal: The Journal of biological chemistry 20020503
Title: Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.
Journal: Human molecular genetics 20020501
Title: Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells.
Journal: Cancer research 20020501
Title: Degradation of RXRs influences sensitivity of rat osteosarcoma cells to the antiproliferative effects of calcitriol.
Journal: Molecular endocrinology (Baltimore, Md.) 20020501
Title: Effect of proteasome inhibitors on the growth, encystation, and excystation of Entamoeba histolytica and Entamoeba invadens.
Journal: Parasitology research 20020501
Title: Differential effects of stress stimuli on a JNK-inactivating phosphatase.
Journal: Oncogene 20020404
Title: Regulation of ornithine decarboxylase and polyamine import by hypoxia in pulmonary artery endothelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20020401
Title: Proteasome inhibitors induce heat shock response and increase IL-6 expression in human intestinal epithelial cells.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20020401
Title: Proteasome implication in phorbol ester- and GnRH-induced selective down-regulation of PKC (alpha, epsilon, zeta) in alpha T(3)-1 and L beta T(2) gonadotrope cell lines.
Journal: Endocrinology 20020401
Title: Impairment of the ubiquitin-proteasome system causes dopaminergic cell death and inclusion body formation in ventral mesencephalic cultures.
Journal: Journal of neurochemistry 20020401
Title: Long term regulation of aquaporin-2 expression in vasopressin-responsive renal collecting duct principal cells.
Journal: The Journal of biological chemistry 20020322
Title: Efficient and qualitatively distinct MHC class I-restricted presentation of antigen targeted to the endoplasmic reticulum.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20020315
Title: Endotoxin stress-response in cardiomyocytes: NF-kappaB activation and tumor necrosis factor-alpha expression.
Journal: American journal of physiology. Heart and circulatory physiology 20020301
Title: Presentation of a new H-2D(k)-restricted epitope in the Tax protein of human T-lymphotropic virus type I is enhanced by the proteasome inhibitor lactacystin.
Journal: The Journal of general virology 20020301
Title: Molecular chaperones enhance the degradation of expanded polyglutamine repeat androgen receptor in a cellular model of spinal and bulbar muscular atrophy.
Journal: Human molecular genetics 20020301
Title: Proteasome inhibition reduces superantigen-mediated T cell activation and the severity of psoriasis in a SCID-hu model.
Journal: The Journal of clinical investigation 20020301
Title: Analysis of Drosophila 26 S proteasome using RNA interference.
Journal: The Journal of biological chemistry 20020222
Title: The molecular basis of glycogen storage disease type 1a: structure and function analysis of mutations in glucose-6-phosphatase.
Journal: The Journal of biological chemistry 20020215
Title: Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation.
Journal: EMBO reports 20020215
Title: Sensitivity of the origin decision point to specific inhibitors of cellular signaling and metabolism.
Journal: Experimental cell research 20020201
Title: Retinal melatonin production: role of proteasomal proteolysis in circadian and photic control of arylalkylamine N-acetyltransferase.
Journal: Investigative ophthalmology & visual science 20020201
Title: Involvement of proteasome in endothelin-1 production in cultured vascular endothelial cells.
Journal: Japanese journal of pharmacology 20020201
Title: Proteasomal degradation of retinoblastoma-related p130 during adipocyte differentiation.
Journal: Biochemical and biophysical research communications 20020125
Title: The glycoprotein gp48 of murine cytomegalovirusL proteasome-dependent cytosolic dislocation and degradation.
Journal: The Journal of biological chemistry 20020118
Title: Chaperone interactions of the metalloproteinase meprin A in the secretory or proteasomal-degradative pathway.
Journal: Archives of biochemistry and biophysics 20020115
Title: Proteasome inhibitors activate the transcription factors C/EBP-beta and delta in human intestinal epithelial cells.
Journal: Biochemical and biophysical research communications 20020111
Title: Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells.
Journal: Carcinogenesis 20020101
Title: Ubiquitin-proteasome pathway is compromised in CD45RO+ and CD45RA+ T lymphocyte subsets during aging.
Journal: Experimental gerontology 20020101
Title: Lipopolysaccharide supports survival and fusion of preosteoclasts independent of TNF-alpha, IL-1, and RANKL.
Journal: Journal of cellular physiology 20020101
Title: Effect of geldanamycin on androgen receptor function and stability.
Journal: Cell stress & chaperones 20020101
Title: Proteasome inhibitors.
Journal: Progress in molecular and subcellular biology 20020101
Title: Differential processing of HLA A2-restricted HIV type 1 cytotoxic T lymphocyte epitopes.
Journal: Viral immunology 20020101
Title: Proteasome inhibitors: complex tools for a complex enzyme.
Journal: Current topics in microbiology and immunology 20020101
Title: A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs).
Journal: BMC cell biology 20020101
Title: Mutant Rab24 GTPase is targeted to nuclear inclusions.
Journal: BMC cell biology 20020101
Title: Numerous proteins in Mammalian cells are prone to iron-dependent oxidation and proteasomal degradation.
Journal: Developmental neuroscience 20020101
Title: Genistein-induced apoptosis of p815 mastocytoma cells is mediated by Bax and augmented by a proteasome inhibitor, lactacystin.
Journal: Nutrition and cancer 20020101
Title: The cyclin-dependent kinase inhibitor butyrolactone is a potent inhibitor of p21 (WAF1/CIP1 expression).
Journal: Cell cycle (Georgetown, Tex.) 20020101
Title: [Embryonal stem cells do not undergo cell cycle arrest upon exposure to damaging factors].
Journal: Tsitologiia 20020101
Title: Proteasome-dependent processing of nuclear proteins is correlated with their subnuclear localization.
Journal: Journal of structural biology 20020101
Title: Lactacystin, a proteasome inhibitor, potentiates the apoptotic effect of parthenolide, an inhibitor of NFkappaB activation, on drug-resistant mouse leukemia L1210 cells.
Journal: Anticancer research 20020101
Title: Differential effect of Bcl-xl over-expression on cell death of the monocytic leukemia cell line U937.
Journal: Anticancer research 20020101
Title: Effects of proteasome inhibitors on the synaptic localization of Vesl-1S/Homer-1a proteins.
Journal: Brain research. Molecular brain research 20011230
Title: Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway.
Journal: The Journal of biological chemistry 20011228
Title: Protease inhibitors restore radiation-induced apoptosis to Bcl-2-expressing lymphoma cells.
Journal: International journal of cancer 20011220
Title: Nedd4 regulates ubiquitination and stability of the guanine-nucleotide exchange factor CNrasGEF.
Journal: The Journal of biological chemistry 20011214
Title: A transcriptionally inactive E2F-1 targets the MDM family of proteins for proteolytic degradation.
Journal: The Journal of biological chemistry 20011207
Title: Redox regulation of human Rac1 stability by the proteasome in human aortic endothelial cells.
Journal: The Journal of biological chemistry 20011207
Title: Photic regulation of melatonin in rat retina and the role of proteasomal proteolysis.
Journal: Neuroreport 20011204
Title: Inhibition of proteasome activity blocks the ability of TNF alpha to down-regulate G(i) proteins and stimulate lipolysis.
Journal: Endocrinology 20011201
Title: Identification and characterization of two novel mutations (Q421 K and R123P) in congenital factor XII deficiency.
Journal: Thrombosis and haemostasis 20011201
Title: The ubiquitin-proteasome cascade is required for mammalian long-term memory formation.
Journal: The European journal of neuroscience 20011201
Title: The proteasome participates in degradation of mutant alpha 1-antitrypsin Z in the endoplasmic reticulum of hepatoma-derived hepatocytes.
Journal: The Journal of biological chemistry 20011130
Title: Divers pathways mediate delta-opioid receptor down regulation within the same cell.
Journal: Brain research. Molecular brain research 20011130
Title: Role of ATP in influenza virus budding.
Journal: Virology 20011125
Title: Ubiquitination precedes internalization and proteolytic cleavage of plasma membrane-bound glycine receptors.
Journal: The Journal of biological chemistry 20011116
Title: Type 1 von Willebrand disease mutation Cys1149Arg causes intracellular retention and degradation of heterodimers: a possible general mechanism for dominant mutations of oligomeric proteins.
Journal: Blood 20011115
Title: Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011115
Title: Regulation of insulin/insulin-like growth factor-1 signaling by proteasome-mediated degradation of insulin receptor substrate-2.
Journal: The Journal of biological chemistry 20011026
Title: A convenient method for 3-pyrroline synthesis.
Journal: Organic letters 20011018
Title: Requirement for Mdm2 in the survival effects of Bcr-Abl and interleukin 3 in hematopoietic cells.
Journal: Cancer research 20011015
Title: Akt1 induces extracellular matrix invasion and matrix metalloproteinase-2 activity in mouse mammary epithelial cells.
Journal: Cancer research 20011015
Title: Proteasome inhibitors differentially affect heat shock protein response in cancer cells.
Journal: International journal of molecular medicine 20011001
Title: Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein.
Journal: The EMBO journal 20011001
Title: Proteasomal degradation of oxidatively damaged endogenous histones in K562 human leukemic cells.
Journal: Free radical biology & medicine 20011001
Title: Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway.
Journal: Molecular cell 20011001
Title: C/EBPbeta phosphorylation by RSK creates a functional XEXD caspase inhibitory box critical for cell survival.
Journal: Molecular cell 20011001
Title: Proteasome activity is critical for the cAMP-induced differentiation of neuroblastoma cells.
Journal: Cellular and molecular neurobiology 20011001
Title: Glycosylation increases potassium channel stability and surface expression in mammalian cells.
Journal: The Journal of biological chemistry 20010907
Title: Neutrophils process exogenous bacteria via an alternate class I MHC processing pathway for presentation of peptides to T lymphocytes.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010901
Title: Efficient presentation of both cytosolic and endogenous transmembrane protein antigens on MHC class II is dependent on cytoplasmic proteolysis.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010901
Title: A measles virus glycoprotein-derived human CTL epitope is abundantly presented via the proteasomal-dependent MHC class I processing pathway.
Journal: The Journal of general virology 20010901
Title: Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex.
Journal: Leukemia 20010901
Title: H(2)O(2)-mediated oxidative stress activates NF-kappa B in lens epithelial cells.
Journal: Free radical biology & medicine 20010901
Title: Proteolysis of oxidized proteins after oxygen-glucose deprivation in rat cortical neurons is mediated by the proteasome.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010901
Title: Antigen processing for MHC class I restricted presentation of exogenous influenza A virus nucleoprotein by B-lymphoblastoid cells.
Journal: Clinical and experimental immunology 20010901
Title: Molecular therapy for multiple myeloma.
Journal: Haematologica 20010901
Title: Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits.
Journal: Chemistry & biology 20010901
Title: Proteasome inhibitors induce Fas-mediated apoptosis by c-Myc accumulation and subsequent induction of FasL message in human glioma cells.
Journal: FEBS letters 20010824
Title: Proteasome inhibitors and immunosuppressive drugs promote the cleavage of eIF4GI and eIF4GII by caspase-8-independent mechanisms in Jurkat T cell lines.
Journal: FEBS letters 20010817
Title: Effects of lipofectin-antigen complexes on major histocompatibility complex class I-restricted antigen presentation pathway in murine dendritic cells and on dendritic cell maturation.
Journal: Biochimica et biophysica acta 20010815
Title: The human type 2 iodothyronine deiodinase is a selenoprotein highly expressed in a mesothelioma cell line.
Journal: The Journal of biological chemistry 20010810
Title: Dendritic growth induced by BMP-7 requires Smad1 and proteasome activity.
Journal: Journal of neurobiology 20010801
Title: Preventive effect of lactacystin, a selective proteasome inhibitor, on ischemic acute renal failure in rats.
Journal: The Journal of pharmacology and experimental therapeutics 20010801
Title: Unexpected transcriptional induction of monocyte chemoattractant protein 1 by proteasome inhibition: involvement of the c-Jun N-terminal kinase-activator protein 1 pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010801
Title: Proteasomal inhibition leads to formation of ubiquitin/alpha-synuclein-immunoreactive inclusions in PC12 cells.
Journal: Journal of neurochemistry 20010801
Title: Preconditioning-induced neuroprotection is mediated by reactive oxygen species and activation of the transcription factor nuclear factor-kappaB.
Journal: Journal of neurochemistry 20010801
Title: Reversion of temperature-sensitive mutation by inhibition of proteasome-mediated degradation of mutated D123 protein.
Journal: Cell structure and function 20010801
Title: Liver alcohol dehydrogenase is degraded by the ubiquitin-proteasome pathway.
Journal: Biochemical and biophysical research communications 20010720
Title: Hypoxia-inducible factor-1 alpha (HIF-1 alpha) escapes O(2)-driven proteasomal degradation irrespective of its subcellular localization: nucleus or cytoplasm.
Journal: EMBO reports 20010707
Title: Glucose regulates protein catabolism in ras-transformed fibroblasts through a lysosomal-dependent proteolytic pathway.
Journal: The Biochemical journal 20010701
Title: Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production.
Journal: Journal of neurochemistry 20010701
Title: Transcriptionally and post-transcriptionally regulated response of 13 calmodulin genes to tobacco mosaic virus-induced cell death and wounding in tobacco plant.
Journal: European journal of biochemistry 20010701
Title: Activation of ATP-ubiquitin-dependent proteolysis in skeletal muscle in vivo and murine myoblasts in vitro by a proteolysis-inducing factor (PIF).
Journal: British journal of cancer 20010701
Title: Inducible nitric-oxide synthase is regulated by the proteasome degradation pathway.
Journal: The Journal of biological chemistry 20010629
Title: An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin.
Journal: Cell 20010629
Title: Activation of NFkappaB and MnSOD gene expression by free radical scavengers in human microvascular endothelial cells.
Journal: Free radical biology & medicine 20010615
Title: Stimulation of HIV gp120-specific cytolytic T lymphocyte responses in vitro and in vivo using a detoxified pertussis toxin vector.
Journal: AIDS research and human retroviruses 20010610
Title: Clustering of peptide-loaded MHC class I molecules for endoplasmic reticulum export imaged by fluorescence resonance energy transfer.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010601
Title: Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite.
Journal: Free radical biology & medicine 20010601
Title: Deoxycholic acid suppresses p53 by stimulating proteasome-mediated p53 protein degradation.
Journal: Carcinogenesis 20010601
Title: cDNA expression arrays: the effects of lactacystin in lipopolysaccharide-induced cystitis.
Journal: Urology 20010601
Title: Nuclear factor-kappaB is constitutively active in C-cell carcinoma and required for RET-induced transformation.
Journal: Cancer research 20010601
Title: Antitumor bicyclic hexapeptide RA-VII modulates cyclin D1 protein level.
Journal: Anti-cancer drugs 20010601
Title: Dexamethasone inhibits TNF-alpha-induced apoptosis and IAP protein downregulation in MCF-7 cells.
Journal: British journal of pharmacology 20010601
Title: Impairment of the ubiquitin-proteasome system by protein aggregation.
Journal: Science (New York, N.Y.) 20010525
Title: Down-regulation of MET, the receptor for hepatocyte growth factor.
Journal: Oncogene 20010517
Title: Glutathiolation of the proteasome is enhanced by proteolytic inhibitors.
Journal: Archives of biochemistry and biophysics 20010515
Title: A constitutive cytoprotective pathway protects endothelial cells from lipopolysaccharide-induced apoptosis.
Journal: The Journal of biological chemistry 20010504
Title: A novel enantioselective synthetic route to omuralide analogues with the potential for species selectivity in proteasome inhibition.
Journal: Organic letters 20010503
Title: Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation.
Journal: European journal of biochemistry 20010501
Title: Protein oxidation and proteolysis in RAW264.7 macrophages: effects of PMA activation.
Journal: Biochimica et biophysica acta 20010423
Title: Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis.
Journal: Human molecular genetics 20010415
Title: Proteasome- and p38-dependent regulation of ERK3 expression.
Journal: The Journal of biological chemistry 20010406
Title: BCR-ABL down-regulates the DNA repair protein DNA-PKcs.
Journal: Blood 20010401
Title: Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
Journal: Blood 20010401
Title: The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome.
Journal: Molecular endocrinology (Baltimore, Md.) 20010401
Title: Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression.
Journal: Biochemical pharmacology 20010401
Title: The levels of MDM2 protein are decreased by a proteasome-mediated proteolysis prior to caspase-3-dependent pRb and PARP cleavages.
Journal: Journal of Korean medical science 20010401
Title: Apolipoprotein E in macrophages and hepatocytes is eegraded via the proteasomal pathway.
Journal: Biochemical and biophysical research communications 20010330
Title: Proteasome activity is required for T lymphocyte aggregation after mitogen activation.
Journal: Journal of cellular biochemistry 20010326
Title: Tumor necrosis factor-alpha induces distinctive NF-kappa B signaling within human dermal fibroblasts.
Journal: The Journal of biological chemistry 20010302
Title: Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010301
Title: A mutation of the Wilson disease protein, ATP7B, is degraded in the proteasomes and forms protein aggregates.
Journal: Gastroenterology 20010301
Title: Use of short-lived green fluorescent protein for the detection of proteasome inhibition.
Journal: BioTechniques 20010301
Title: UCN-01 suppresses E2F-1 mediated by ubiquitin-proteasome-dependent degradation.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20010301
Title: Pro-caspase-3 overexpression sensitises ovarian cancer cells to proteasome inhibitors.
Journal: Cell death and differentiation 20010301
Title: c-Jun NH2-terminal kinase-mediated redox-dependent degradation of IkappaB: role of thioredoxin in NF-kappaB activation.
Journal: The Journal of biological chemistry 20010216
Title: 3-hydroxy-3-methylglutaryl coenzyme A reductase is sterol-dependently cleaved by cathepsin L-type cysteine protease in the isolated endoplasmic reticulum.
Journal: Archives of biochemistry and biophysics 20010215
Title: Newly synthesized human delta opioid receptors retained in the endoplasmic reticulum are retrotranslocated to the cytosol, deglycosylated, ubiquitinated, and degraded by the proteasome.
Journal: The Journal of biological chemistry 20010209
Title: Influence of proteasome and redox state on heat shock-induced activation of stress kinases, AP-1 and HSF.
Journal: Biochimica et biophysica acta 20010205
Title: IFN-beta mediates coordinate expression of antigen-processing genes in RSV-infected pulmonary epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010201
Title: Oxidative stress inhibits the mitochondrial import of preproteins and leads to their degradation.
Journal: Experimental cell research 20010201
Title: Tunicamycin induces ubiquitination and degradation of apolipoprotein B in HepG2 cells.
Journal: The Biochemical journal 20010201
Title: Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult.
Journal: Journal of neurochemistry 20010201
Title: The ubiquitin-proteasome pathway plays an essential role in proteolysis during Trypanosoma cruzi remodeling.
Journal: Biochemistry 20010130
Title: Proteasomal function is impaired in substantia nigra in Parkinson's disease.
Journal: Neuroscience letters 20010119
Title: The proteasome regulates receptor-mediated endocytosis of interleukin-2.
Journal: The Journal of biological chemistry 20010105
Title: Ubiquitination of Lyn-kinase in rat basophilic leukemia RBL-2H3 cells.
Journal: Immunology letters 20010101
Title: Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation.
Journal: Diabetes 20010101
Title: Inhibition of proteasome activity by the TED4 protein in extracellular space: a novel mechanism for protection of living cells from injury caused by dying cells.
Journal: Plant & cell physiology 20010101
Title: Proinflammatory cytokines and CD40 ligand enhance cross-presentation and cross-priming capability of human dendritic cells internalizing apoptotic cancer cells.
Journal: Journal of immunotherapy (Hagerstown, Md. : 1997) 20010101
Title: Coordinate regulation of RARgamma2, TBP, and TAFII135 by targeted proteolysis during retinoic acid-induced differentiation of F9 embryonal carcinoma cells.
Journal: BMC molecular biology 20010101
Title: Inhibition of NF-kappa B with proteasome inhibitors enhances apoptosis in human lung adenocarcinoma cells in vitro.
Journal: Anticancer research 20010101
Title: [Effect of EGF on nuclear-cytoplasmic distribution of proteasomes in A-431 cells].
Journal: Tsitologiia 20010101
Title: Characterization of membrane-associated proteasomes in WB rat liver epithelial cells.
Journal: Archives of biochemistry and biophysics 20010101
Title: Lactacystin inhibits cathepsin A activity in melanoma cell lines.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20010101
Title: Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons.
Journal: Neuroscience 20010101
Title: Lactacystin enhances cisplatin sensitivity in resistant human ovarian cancer cell lines via inhibition of DNA repair and ERCC-1 expression.
Journal: Cellular and molecular biology (Noisy-le-Grand, France) 20010101
Title: Proteasome inhibitors block intracellular growth and replication of Toxoplasma gondii.
Journal: Parasitology 20000701
Title: Superinduction of CYP1A1 gene expression. Regulation of 2,3,7, 8-tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide.
Journal: The Journal of biological chemistry 20000428
Title: 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway. Role of the transcription activaton and DNA binding of AhR.
Journal: The Journal of biological chemistry 20000324
Title: Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K(+)-ATPase through proteasomal and endo-/lysosomal proteolytic pathways.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19991001
Title: Differential inhibition of three peptidase activities of the proteasome in human lens epithelium by heat and oxidation.
Journal: Experimental eye research 19990701
Title: Csizmadia V, et al. Effect of proteasome inhibitors with different chemical structures on the ubiquitin-proteasomesystem in vitro. Vet Pathol. 2010 Mar;47(2):358-67.
Title: Savolainen MH, et al. Nigral injection of a proteasomal inhibitor, lactacystin, induces widespread glial cell activationand shows various phenotypes of Parkinson's disease in young and adult mouse. Exp Brain Res. 2017 Jul;235(7):2189-2202.
