Name: Name:1-(2,2,2-Trifluoroethyl)piperazine
Brand: AABLOCKS
SKU: AA009FXB
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA009FXB

Chemical Name: 1-(2,2,2-Trifluoroethyl)piperazine

CAS Number: 13349-90-1

Molecular Formula: C6H11F3N2

Molecular Weight: 168.1601

MDL Number: MFCD08444233

SMILES: FC(CN1CCNCC1)(F)F

Properties

Complexity: 118

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 11

Hydrogen Bond Acceptor Count: 5

Hydrogen Bond Donor Count: 1

Isotope Atom Count: 0

Rotatable Bond Count: 1

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 0.7

Downstream Synthesis Route

13349-90-1

226575-72-0

7-chloro-5-4-(2,2,2-trifluoro-ethyl)-piperazine-1-carbonyl-4,5-dihydro-imidazo1,5-aquinoxaline-3-carboxylicacidtert-butylester

[1]Jacobsen,E.Jon;Stelzer,LindsayS.;TenBrink,RuthE.;Belonga,KennethL.;Carter,DonaldB.;Im,HaesookK.;Im,WhaBin;Sethy,VimalaH.;Tang,AndyH.;VonVoigtlander,PhilipF.;Petke,JamesD.;Zhong,Wei-Zhu;Mickelson,JohnW.[JournalofMedicinalChemistry,1999,vol.42,#7,p.1123-1144]

890300-37-5

13349-90-1

3,3'-difluoro-4'-({5-4-(2,2,2-trifluoro-ethyl)-piperazine-1-carbonyl-pyridin-2-ylamino}-methyl)-biphenyl-2-carboxylicacidmethylester

[1]Kuduk,ScottD.;DiMarco,ChristinaNg;Chang,RonaldK.;Wood,MichaelR.;Kim,JuneJ.;Schirripa,KathyM.;Murphy,KathyL.;Ransom,RichardW.;Tang,Cuyue;Torrent,Maricel;Ha,Sookhee;Prueksaritanont,Thomayant;Pettibone,DouglasJ.;Bock,MarkG.[BioorganicandMedicinalChemistryLetters,2006,vol.16,#10,p.2791-2795]

1-(4-chloro-phenoxy)-9-(3-fluoro-piperidin-4-ylmethyl)-9H-carbazole-3-carboxylicacid

13349-90-1

1-(4-chloro-phenoxy)-9-(3-fluoro-piperidin-4-ylmethyl)-9H-carbazol-3-yl-4-(2,2,2-trifluoro-ethyl)-piperazin-1-yl-methanone

[1]Leslie,ColinP.;Fabio,RomanoDi;Bonetti,Francesca;Borriello,Manuela;Braggio,Simone;Forno,GiovannaDal;Donati,Daniele;Falchi,Alessandro;Ghirlanda,Damiano;Giovannini,Riccardo;Pavone,Francesca;Pecunioso,Angelo;Pentassuglia,Giorgio;Pizzi,DomenicaA.;Rumboldt,Giovanna;Stasi,Luigi[BioorganicandMedicinalChemistryLetters,2007,vol.17,#4,p.1043-1046]

tert-butyl4-(2,2,2-trifluoroethyl)piperazine-1-carboxylate

13349-90-1

[1]Wang,Hui-Ling;Katon,Jodie;Balan,Chenera;Bannon,AnthonyW.;Bernard,Charles;Doherty,ElizabethM.;Dominguez,Celia;Gavva,NarenderR.;Gore,Vijay;Ma,Vu;Nishimura,Nobuko;Surapaneni,Sekhar;Tang,Phi;Tamir,Rami;Thiel,Oliver;Treanor,JamesJ.S.;Norman,MarkH.[JournalofMedicinalChemistry,2007,vol.50,#15,p.3528-3539]

13349-90-1 | 1-(2,2,2-Trifluoroethyl)piperazine