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Home Other Building Blocks 133550-37-5
133550-37-5,MFCD00209855
Catalog No.:AA00395G

133550-37-5 | Tyrphostin ag 835

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Purity
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Price(USD)
Quantity
  
25mg
>98.0%(HPLC)
in stock  
$127.00   $89.00
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  • Technical Information
  • Properties
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00395G
Chemical Name:
Tyrphostin ag 835
CAS Number:
133550-37-5
Molecular Formula:
C18H16N2O3
Molecular Weight:
308.3312
MDL Number:
MFCD00209855
SMILES:
N#C/C(=C\c1ccc(c(c1)O)O)/C(=O)N[C@H](c1ccccc1)C
Properties
Computed Properties
 
Complexity:
488  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
XLogP3:
2.7  

Literature

Title: S-adenosylmethionine-dependent protein methylation in mammalian cytosol via tyrphostin modification by catechol-O-methyltransferase.

Journal: The Journal of biological chemistry 20071019

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases.

Journal: Journal of medicinal chemistry 19910601

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