Home Other Building Blocks 133718-30-6
133718-30-6,MFCD30489748
Catalog No.:AA009CKV

133718-30-6 | R 80123

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Purity
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1mg
98%
1 week  
$177.00   $124.00
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA009CKV
Chemical Name:
R 80123
CAS Number:
133718-30-6
Molecular Formula:
C26H29N5O3
Molecular Weight:
459.5402
MDL Number:
MFCD30489748
SMILES:
O=C1CN2C(=Nc3c(C2)cc(cc3)/C(=N\OCC(=O)N(C2CCCCC2)C)/c2ccccc2)N1
Properties
Computed Properties
 
Complexity:
815  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
Undefined Bond Stereocenter Count:
1  
XLogP3:
3.6  

Literature

Title: Vandeplassche GM et al. Comparative effects of R 80122, enoximone, and milrinone on left ventricular phosphodiesterase isoenzymes in vitro and on contractility of normal and stunned myocardium in vivo in dogs. J Cardiovasc Pharmacol. 1992 May;19(5):714-22.https://www.ncbi.nlm.nih.gov/pubmed/ 1381769

Title: Schneider J et al. Cardiac effects of R 79595 and its isomers (R 80122 and R 80123) in an acute heart failure model. A new class of cardiotonic agents with highly selective phosphodiesterase III inhibitory properties.Naunyn Schmiedebergs Arch Pharmacol. 1992 Nov;346(5):563-72.

Title: Vandeplassche GM et al. Comparative effects of R 80122, enoximone, and milrinone on left ventricular phosphodiesterase isoenzymes in vitro and on contractility of normal and stunned myocardium in vivo in dogs. J Cardiovasc Pharmacol. 1992 May;19(5):714-22.

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Tags:133718-30-6 Molecular Formula|133718-30-6 MDL|133718-30-6 SMILES|133718-30-6 R 80123