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134052-66-7,MFCD00216828
Catalog No.:AA00801J

134052-66-7 | Benzeneacetic acid, a-amino-4-carboxy-3-hydroxy-

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  • Properties
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00801J
Chemical Name:
Benzeneacetic acid, a-amino-4-carboxy-3-hydroxy-
CAS Number:
134052-66-7
Molecular Formula:
C9H9NO5
Molecular Weight:
211.1715
MDL Number:
MFCD00216828
SMILES:
NC(c1ccc(c(c1)O)C(=O)O)C(=O)O
Properties
Computed Properties
 
Complexity:
267  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
3  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-1  

Literature

Title: 5-HT1A autoreceptor modulation of locomotor activity induced by nitric oxide in the rat dorsal raphe nucleus.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20110401

Title: [Effect of (S)-4C3HPG on brain damage in the acute stage of moderate traumatic brain injury model of mice and underlying mechanism].

Journal: Sheng li xue bao : [Acta physiologica Sinica] 20101225

Title: Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis.

Journal: Neuropharmacology 20050101

Title: Antagonism of group I metabotropic glutamate receptors and PLC attenuates increases in inositol trisphosphate and reduces reactive gliosis in strain-injured astrocytes.

Journal: Journal of neurotrauma 20040201

Title: [Effects of the metabotropic glutamate receptor ligand(s)-4C3HPG on the induction of brain ischemic tolerance in the rat].

Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20030201

Title: Glutamate receptors communicate with Na+/K+-ATPase in rat cerebellum granule cells: demonstration of differences in the action of several metabotropic and ionotropic glutamate agonists on intracellular reactive oxygen species and the sodium pump.

Journal: Journal of molecular neuroscience : MN 20030101

Title: Neuroprotection mediated by glial group-II metabotropic glutamate receptors requires the activation of the MAP kinase and the phosphatidylinositol-3-kinase pathways.

Journal: Journal of neurochemistry 20010801

Title: Attenuation of seizures induced by homocysteic acid in immature rats by metabotropic glutamate group II and group III receptor agonists.

Journal: Brain research 20010727

Title: (S)-4C3HPG, a mixed group I mGlu receptor antagonist and a group II agonist, administered intrastriatally, counteracts parkinsonian-like muscle rigidity in rats.

Journal: Brain research 20010608

Title: Regional distribution and pharmacological characteristics of [3H]N-acetyl-aspartyl-glutamate (NAAG) binding sites in rat brain.

Journal: Neurochemistry international 20010101

Title: Characterization of [(3)H]Quisqualate binding to recombinant rat metabotropic glutamate 1a and 5a receptors and to rat and human brain sections.

Journal: Journal of neurochemistry 20001201

Title: The role of metabotropic glutamate receptor (mGluR) ligands in parkinsonian muscle rigidity.

Journal: Amino acids 20000101

Title: Pharmacological analysis of 4-carboxyphenylglycine derivatives: comparison of effects on mGluR1 alpha and mGluR5a subtypes.

Journal: Neuropharmacology 19950801

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