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1342820-51-2,MFCD28505586
Catalog No.:AA003API

1342820-51-2 | MC-Val-Ala-PBD

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1mg
95%
1 week  
$1,558.00   $1,091.00
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5mg
95%
1 week  
$4,495.00   $3,147.00
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Technical Information
Catalog Number:
AA003API
Chemical Name:
MC-Val-Ala-PBD
CAS Number:
1342820-51-2
Molecular Formula:
C60H64N8O12
Molecular Weight:
1089.1966
MDL Number:
MFCD28505586
SMILES:
COc1cc2c(cc1OCCCOc1cc3N=C[C@H]4N(C(=O)c3cc1OC)C=C(C4)c1ccc(cc1)OC)N=C[C@H]1N(C2=O)C=C(C1)c1ccc(cc1)NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)CCCCCN1C(=O)C=CC1=O)C
Properties

Literature

Title: John A Hartley. Antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) dimers for cancer therapy. Expert Opin Biol Ther. 2020 Jun 16;1-13.

Title: Jeffrey SC, et al. A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology. Bioconjug Chem. 2013 Jul 17;24(7):1256-63.

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SDS
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