Home Other Building Blocks 13441-51-5
13441-51-5,MFCD00133224
Catalog No.:AA003GB6

13441-51-5 | D-Kynurenine

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Purity
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Price(USD)
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25mg
95%
in stock  
$78.00   $54.00
- +
50mg
95%
in stock  
$129.00   $90.00
- +
100mg
95%
in stock  
$206.00   $144.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003GB6
Chemical Name:
D-Kynurenine
CAS Number:
13441-51-5
Molecular Formula:
C10H12N2O3
Molecular Weight:
208.2139
MDL Number:
MFCD00133224
SMILES:
OC(=O)[C@@H](CC(=O)c1ccccc1N)N
Properties
Properties
 
BP:
466.556°C at 760 mmHg  
Form:
Solid  
Storage:
Keep in dry area;2-8℃;  


Downstream Synthesis Route

[1]CurrentPatentAssignee:THEUNIVERSITYOFTEXASSYSTEM-WO2010/148191,2010,A2Locationinpatent:Page/Pagecolumn45-49;61

[2]Hellinghausen,Garrett;Lopez,DiegoA.;Lee,JauhT.;Wang,Yadi;Weatherly,ChoyceA.;Portillo,AbiudE.;Berthod,Alain;Armstrong,DanielW.[Chirality,2018,vol.30,#9,p.1067-1078]

[1]Locationinpatent:bodytextPearson,JoshT.;Siu,Sophia;Meininger,DavidP.;Wienkers,LarryC.;Rock,DanA.[Biochemistry,2010,vol.49,#12,p.2647-2656]

(S)-4-(3-isothiocyanatopyrrolidin-1-yl)-7-(N,N-dimethylaminosulfonyl)-2,1,3-benzoxadiazole 
  13441-51-5   
(S)-DBD-PyNCS-D-KYN 

[1]Iizuka,Hideaki;Harashima,Takahiro;Takahashi,Shuhei;Kuwabara,Ryosuke;Naito,Yoko;Sakamoto,Tatsuya;Onozato,Mayu;Ichiba,Hideaki;Fukushima,Takeshi[Chirality,2017,vol.29,#10,p.603-609]

Literature

Title: Wang XD, et al. A method for the determination of D-kynurenine in biological tissues. Anal Bioanal Chem. 2013 Dec;405(30):9747-54.

Title: Irukayama-Tomobe Y, et al. Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3930-4.

Title: Kozaki A, et al. Fluorimetric assay for D-amino acid oxidase activity in rat brain homogenate by using D-kynurenine as a substrate. Biosci Trends. 2012 Oct;6(5):241-7.

Title: Duan Z, et al. Promoting epithelial-to-mesenchymal transition by D-kynurenine via activating aryl hydrocarbon receptor. Mol Cell Biochem. 2018 Nov;448(1-2):165-173.

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