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Home Fluorides 1346528-50-4
1346528-50-4,MFCD29047142
Catalog No.:AA009CI7

1346528-50-4 | N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98+%
in stock  
$39.00   $28.00
- +
100mg
98%
in stock  
$618.00   $433.00
- +
250mg
98%
in stock  
$1,233.00   $863.00
- +
1g
98%
in stock  
$3,070.00   $2,149.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA009CI7
Chemical Name:
N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide
CAS Number:
1346528-50-4
Molecular Formula:
C18H17ClF2N4O3
Molecular Weight:
410.8024
MDL Number:
MFCD29047142
SMILES:
O=C(N1CCN(CC1)Cc1ccc2c(c1)OC(O2)(F)F)Nc1cnccc1Cl
Properties
Computed Properties
 
Complexity:
565  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
2.6  

Literature

Title: Preclinical Characterization of the FAAH Inhibitor JNJ-42165279.

Journal: ACS medicinal chemistry letters 20151210

Title: Inhibition of fatty acid amide hydrolase (FAAH) as a novel therapeutic strategy in the treatment of pain and inflammatory diseases in the gastrointestinal tract.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20140214

Title: Elevating endocannabinoid levels: pharmacological strategies and potential therapeutic applications.

Journal: The Proceedings of the Nutrition Society 20140201

Title: Pharmacotherapeutic modulation of the endocannabinoid signalling system in psychiatric disorders: drug-discovery strategies.

Journal: International review of psychiatry (Abingdon, England) 20090401

Title: Keith JM, et al. Preclinical Characterization of the FAAH Inhibitor JNJ-42165279. ACS Med Chem Lett. 2015 Nov 2;6(12):1204-8.

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Tags:1346528-50-4 Molecular Formula|1346528-50-4 MDL|1346528-50-4 SMILES|1346528-50-4 N-(4-chloropyridin-3-yl)-4-((2,2-difluorobenzo[d][1,3]dioxol-5-yl)Methyl)piperazine-1-carboxaMide