Title: Positron emission tomography/computed tomography imaging of residual skull base chordoma before radiotherapy using fluoromisonidazole and fluorodeoxyglucose: potential consequences for dose painting.
Journal: International journal of radiation oncology, biology, physics 20121101
Title: Dose-response relationships of FMISO between trace dose and various macro-doses in rat by ultra-performance liquid chromatography with mass spectrometry and radioactivity analysis.
Journal: Journal of pharmaceutical and biomedical analysis 20121101
Title: Evaluation of changes in the tumor microenvironment after sorafenib therapy by sequential histology and 18F-fluoromisonidazole hypoxia imaging in renal cell carcinoma.
Journal: International journal of oncology 20121101
Title: Tumor microenvironment-dependent 18F-FDG, 18F-fluorothymidine, and 18F-misonidazole uptake: a pilot study in mouse models of human non-small cell lung cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120801
Title: Design, synthesis, and preliminary biological evaluation of 6-O-glucose-azomycin adducts for diagnosis and therapy of hypoxic tumors.
Journal: Journal of medicinal chemistry 20120712
Title: Hypoxia assessed by 18F-fluoromisonidazole positron emission tomography in newly diagnosed gliomas.
Journal: Nuclear medicine communications 20120601
Title: ¹⁸F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas.
Journal: European journal of nuclear medicine and molecular imaging 20120501
Title: Modelling and simulation of the influence of acute and chronic hypoxia on [18F]fluoromisonidazole PET imaging.
Journal: Physics in medicine and biology 20120321
Title: Applying a patient-specific bio-mathematical model of glioma growth to develop virtual [18F]-FMISO-PET images.
Journal: Mathematical medicine and biology : a journal of the IMA 20120301
Title: Implementation of hypoxia measurement into lung cancer therapy.
Journal: Lung cancer (Amsterdam, Netherlands) 20120201
Title: Reoxygenation of glioblastoma multiforme treated with fractionated radiotherapy concomitant with temozolomide: changes defined by 18F-fluoromisonidazole positron emission tomography: two case reports.
Journal: Japanese journal of clinical oncology 20120201
Title: The role of surgery, radiosurgery and whole brain radiation therapy in the management of patients with metastatic brain tumors.
Journal: International journal of surgical oncology 20120101
Title: Tumor blood flow differs between mouse strains: consequences for vasoresponse to photodynamic therapy.
Journal: PloS one 20120101
Title: Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy.
Journal: Frontiers in pharmacology 20120101
Title: Hypoxia imaging with [F-18] FMISO-PET in head and neck cancer: potential for guiding intensity modulated radiation therapy in overcoming hypoxia-induced treatment resistance.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20111201
Title: Lack of concordance between the F-18 fluoromisonidazole PET and the F-18 FDG PET in human glioblastoma.
Journal: Clinical nuclear medicine 20111201
Title: 18F-fluoromisonidazole positron emission tomography before treatment is a predictor of radiotherapy outcome and survival prognosis in patients with head and neck squamous cell carcinoma.
Journal: Annals of nuclear medicine 20111101
Title: PET imaging of cardiac hypoxia: opportunities and challenges.
Journal: Journal of molecular and cellular cardiology 20111101
Title: Secondary gliosarcoma after the treatment of primary glioblastoma multiforme.
Journal: North American journal of medical sciences 20111101
Title: Anti-VEGF antibody treatment accelerates polycystic kidney disease.
Journal: American journal of physiology. Renal physiology 20111001
Title: Radiotherapy and temozolomide for newly diagnosed glioblastoma and anaplastic astrocytoma: validation of Radiation Therapy Oncology Group-Recursive Partitioning Analysis in the IMRT and temozolomide era.
Journal: Journal of neuro-oncology 20110801
Title: Characterization of positron emission tomography hypoxia tracer uptake and tissue oxygenation via electrochemical modeling.
Journal: Nuclear medicine and biology 20110801
Title: Complementary information from magnetic resonance imaging and (18)F-fluoromisonidazole positron emission tomography in the assessment of the response to an antiangiogenic treatment in a rat brain tumor model.
Journal: Nuclear medicine and biology 20110801
Title: Metastatic renal cell carcinoma: relationship between initial metastasis hypoxia, change after 1 month's sunitinib, and therapeutic response: an 18F-fluoromisonidazole PET/CT study.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110701
Title: In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis.
Journal: PLoS pathogens 20110701
Title: Evaluation of hypoxic tissue dynamics with 18F-FMISO PET in a rat model of permanent cerebral ischemia.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110601
Title: Outcome of stage IVA cervical cancer patients with disease limited to the pelvis in the era of chemoradiation: a Gynecologic Oncology Group study.
Journal: Gynecologic oncology 20110601
Title: Comparison of (immuno-)fluorescence data with serial [¹⁸F]Fmiso PET/CT imaging for assessment of chronic and acute hypoxia in head and neck cancers.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110601
Title: Modelling and simulation of [18F]fluoromisonidazole dynamics based on histology-derived microvessel maps.
Journal: Physics in medicine and biology 20110407
Title: Reduction of [(18)F]fluoromisonidazole uptake after neoadjuvant chemotherapy for head and neck squamous cell carcinoma.
Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110401
Title: Radiosynthesis of the tumor hypoxia marker [18F]TFMISO via O-[18F]trifluoroethylation reveals a striking difference between trifluoroethyl tosylate and iodide in regiochemical reactivity toward oxygen nucleophiles.
Journal: Bioorganic & medicinal chemistry 20110401
Title: Multiagent PET for risk characterization in sarcoma.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110401
Title: Hypofractionation results in reduced tumor cell kill compared to conventional fractionation for tumors with regions of hypoxia.
Journal: International journal of radiation oncology, biology, physics 20110315
Title: 'Salvaged' stroke ischaemic penumbra shows significant injury: studies with the hypoxia tracer FMISO.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110301
Title: Correlation of biological aggressiveness assessed by 11C-methionine PET and hypoxic burden assessed by 18F-fluoromisonidazole PET in newly diagnosed glioblastoma.
Journal: European journal of nuclear medicine and molecular imaging 20110301
Title: 18F-fluromisonidazole PET imaging as a biomarker for the response to 5,6-dimethylxanthenone-4-acetic acid in colorectal xenograft tumors.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110301
Title: Parametric mapping of [18F]fluoromisonidazole positron emission tomography using basis functions.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110201
Title: Molecular imaging of hypoxia.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20110201
Title: Simultaneous positron emission tomography (PET) assessment of metabolism with ¹⁸F-fluoro-2-deoxy-d-glucose (FDG), proliferation with ¹⁸F-fluoro-thymidine (FLT), and hypoxia with ¹⁸fluoro-misonidazole (F-miso) before and during radiotherapy in patients with non-small-cell lung cancer (NSCLC): a pilot study.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110101
Title: Two or four hour [¹⁸F]FMISO-PET in HNSCC. When is the contrast best?
Journal: Nuklearmedizin. Nuclear medicine 20110101
Title: Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells.
Journal: PloS one 20110101
Title: Hypoxia imaging using PET and SPECT: the effects of anesthetic and carrier gas on [Cu]-ATSM, [Tc]-HL91 and [F]-FMISO tumor hypoxia accumulation.
Journal: PloS one 20110101
Title: Theoretical analysis of the dose dependence of the oxygen enhancement ratio and its relevance for clinical applications.
Journal: Radiation oncology (London, England) 20110101
Title: Risk factors of distant brain failure for patients with newly diagnosed brain metastases treated with stereotactic radiotherapy alone.
Journal: Radiation oncology (London, England) 20110101
Title: Contribution of [64Cu]-ATSM PET in molecular imaging of tumour hypoxia compared to classical [18F]-MISO--a selected review.
Journal: Nuclear medicine review. Central & Eastern Europe 20110101
Title: Combined modality approaches in the management of adult glioblastoma.
Journal: Frontiers in oncology 20110101
Title: The possibility of a fully automated procedure for radiosynthesis of fluorine-18-labeled fluoromisonidazole using a simplified single, neutral alumina column purification procedure.
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20101001
Title: Identifying hypoxia in human tumors: A correlation study between 18F-FMISO PET and the Eppendorf oxygen-sensitive electrode.
Journal: Acta oncologica (Stockholm, Sweden) 20101001
Title: PET radiopharmaceuticals in radiation treatment planning - synthesis and biological characteristics.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20100901
Title: Noninvasive assessment of tumor microenvironment using dynamic contrast-enhanced magnetic resonance imaging and 18F-fluoromisonidazole positron emission tomography imaging in neck nodal metastases.
Journal: International journal of radiation oncology, biology, physics 20100801
Title: Pre-clinical evaluation of a 3-nitro-1,2,4-triazole analogue of [18F]FMISO as hypoxia-selective tracer for PET.
Journal: Nuclear medicine and biology 20100701
Title: Simulation of tissue activity curves of (64)Cu-ATSM for sub-target volume delineation in radiotherapy.
Journal: Physics in medicine and biology 20100207
Title: Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity.
Journal: Journal of neuro-oncology 20100201
Title: Influence of manipulating hypoxia in solid tumors on the radiation dose-rate effect in vivo, with reference to that in the quiescent cell population.
Journal: Japanese journal of radiology 20100201
Title: Imaging of hypoxic-ischemic penumbra with (18)F-fluoromisonidazole PET/CT and measurement of related cerebral metabolism in aneurysmal subarachnoid hemorrhage.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20100101
Title: The role of stereotactic radiosurgery in the management of patients with newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal: Journal of neuro-oncology 20100101
Title: The role of whole brain radiation therapy in the management of newly diagnosed brain metastases: a systematic review and evidence-based clinical practice guideline.
Journal: Journal of neuro-oncology 20100101
Title: Pharmacokinetic analysis of hypoxia (18)F-fluoromisonidazole dynamic PET in head and neck cancer.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20100101
Title: Partial pulmonary embolization disrupts alveolarization in fetal sheep.
Journal: Respiratory research 20100101
Title: Definitive radiotherapy and single-agent radiosensitizing ifosfamide in patients with localized, irresectable soft tissue sarcoma: a retrospective analysis.
Journal: Radiation oncology (London, England) 20100101
Title: HIF-1alpha and HIF-2alpha are differentially activated in distinct cell populations in retinal ischaemia.
Journal: PloS one 20100101
Title: A phase I study of the nitroimidazole hypoxia marker SR4554 using 19F magnetic resonance spectroscopy.
Journal: British journal of cancer 20091201
Title: Design of silicon-based misonidazole analogues and (18)F-radiolabelling.
Journal: Nuclear medicine and biology 20091101
Title: A robotic system for 18F-FMISO PET-guided intratumoral pO2 measurements.
Journal: Medical physics 20091101
Title: Modeling acute and chronic hypoxia using serial images of 18F-FMISO PET.
Journal: Medical physics 20091001
Title: Characterisation of the timing of binding of the hypoxia tracer FMISO after stroke.
Journal: Brain research 20090908
Title: Prospective trial incorporating pre-/mid-treatment [18F]-misonidazole positron emission tomography for head-and-neck cancer patients undergoing concurrent chemoradiotherapy.
Journal: International journal of radiation oncology, biology, physics 20090901
Title: Evaluation of a compartmental model for estimating tumor hypoxia via FMISO dynamic PET imaging.
Journal: Physics in medicine and biology 20090521
Title: Quantitative metrics of net proliferation and invasion link biological aggressiveness assessed by MRI with hypoxia assessed by FMISO-PET in newly diagnosed glioblastomas.
Journal: Cancer research 20090515
Title: Biodistribution, pharmacokinetics and PET imaging of [(18)F]FMISO, [(18)F]FDG and [(18)F]FAc in a sarcoma- and inflammation-bearing mouse model.
Journal: Nuclear medicine and biology 20090401
Title: Noninvasive multimodality imaging of the tumor microenvironment: registered dynamic magnetic resonance imaging and positron emission tomography studies of a preclinical tumor model of tumor hypoxia.
Journal: Neoplasia (New York, N.Y.) 20090301
Title: [Advances in research on hypoxic imaging in cancer radiotherapy].
Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090301
Title: Cytotoxic palladium complexes of bioreductive quinoxaline N1,N4-dioxide prodrugs.
Journal: Bioorganic & medicinal chemistry 20090215
Title: [18F]EF3 is not superior to [18F]FMISO for PET-based hypoxia evaluation as measured in a rat rhabdomyosarcoma tumour model.
Journal: European journal of nuclear medicine and molecular imaging 20090201
Title: Complementary but distinct roles for MRI and 18F-fluoromisonidazole PET in the assessment of human glioblastomas.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090101
Title: Whole brain radiotherapy with radiosensitizer for brain metastases.
Journal: Journal of experimental & clinical cancer research : CR 20090101
Title: Stereotactic radiosurgery for glioblastoma: retrospective analysis.
Journal: Radiation oncology (London, England) 20090101
Title: Expression and function of hypoxia inducible factor-1 alpha in human melanoma under non-hypoxic conditions.
Journal: Molecular cancer 20090101
Title: Comparative pharmacokinetics, biodistribution, metabolism and hypoxia-dependent uptake of [18F]-EF3 and [18F]-MISO in rodent tumor models.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20081201
Title: Noninvasive molecular imaging of hypoxia in human xenografts: comparing hypoxia-induced gene expression with endogenous and exogenous hypoxia markers.
Journal: Cancer research 20081015
Title: Correlation of [18F]FMISO autoradiography and pimonidazole [corrected] immunohistochemistry in human head and neck carcinoma xenografts.
Journal: European journal of nuclear medicine and molecular imaging 20081001
Title: Autoradiographic and small-animal PET comparisons between (18)F-FMISO, (18)F-FDG, (18)F-FLT and the hypoxic selective (64)Cu-ATSM in a rodent model of cancer.
Journal: Nuclear medicine and biology 20080801
Title: Enhanced local tumour control after single or fractionated radiation treatment using the hypoxic cell radiosensitizer doranidazole.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20080601
Title: Novel imaging approaches to head and neck cancer.
Journal: Seminars in oncology 20080601
Title: Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: correlation with time to progression and survival.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080501
Title: The influence of changes in tumor hypoxia on dose-painting treatment plans based on 18F-FMISO positron emission tomography.
Journal: International journal of radiation oncology, biology, physics 20080315
Title: Tumor hypoxia imaging in orthotopic liver tumors and peritoneal metastasis: a comparative study featuring dynamic 18F-MISO and 124I-IAZG PET in the same study cohort.
Journal: European journal of nuclear medicine and molecular imaging 20080101
Title: Fluorine-18-labeled fluoromisonidazole positron emission and computed tomography-guided intensity-modulated radiotherapy for head and neck cancer: a feasibility study.
Journal: International journal of radiation oncology, biology, physics 20080101
Title: Reproducibility of intratumor distribution of (18)F-fluoromisonidazole in head and neck cancer.
Journal: International journal of radiation oncology, biology, physics 20080101
Title: PET for sarcomas other than gastrointestinal stromal tumors.
Journal: The oncologist 20080101
Title: Biological image-guided radiotherapy in rectal cancer: is there a role for FMISO or FLT, next to FDG?
Journal: Acta oncologica (Stockholm, Sweden) 20080101
Title: Neuropsychological testing and biomarkers in the management of brain metastases.
Journal: Radiation oncology (London, England) 20080101
Title: Hypoxia positron emission tomography imaging with 18f-fluoromisonidazole.
Journal: Seminars in nuclear medicine 20071101
Title: Interventions for preventing oral mucositis for patients with cancer receiving treatment.
Journal: The Cochrane database of systematic reviews 20071017
Title: Altered calcium homeostasis in motor neurons following AMPA receptor but not voltage-dependent calcium channels' activation in a genetic model of amyotrophic lateral sclerosis.
Journal: Neurobiology of disease 20071001
Title: [Molecular design of hypoxic tumor cell-targeting drugs and imaging probes].
Journal: Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20071001
Title: Experimental hypoxia is a potent stimulus for radiotracer uptake in vitro: comparison of different tumor cells and primary endothelial cells.
Journal: Cancer letters 20070828
Title: In vivo 19F magnetic resonance spectroscopy and chemical shift imaging of tri-fluoro-nitroimidazole as a potential hypoxia reporter in solid tumors.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20070615
Title: A robotic synthesis of [18F]fluoromisonidazole ([18F]FMISO).
Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20070601
Title: A model of reoxygenation dynamics of head-and-neck tumors based on serial 18F-fluoromisonidazole positron emission tomography investigations.
Journal: International journal of radiation oncology, biology, physics 20070601
Title: In vivo molecular imaging biomarkers: clinical pharmacology's new 'PET'?
Journal: Clinical pharmacology and therapeutics 20070601
Title: Hypoxia-imaging with (18)F-Misonidazole and PET: changes of kinetics during radiotherapy of head-and-neck cancer.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070601
Title: Canadian recommendations for the treatment of glioblastoma multiforme.
Journal: Current oncology (Toronto, Ont.) 20070601
Title: Hypoxia dose painting by numbers: a planning study.
Journal: International journal of radiation oncology, biology, physics 20070501
Title: Imaging of brain hypoxia in permanent and temporary middle cerebral artery occlusion in the rat using 18F-fluoromisonidazole and positron emission tomography: a pilot study.
Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070401
Title: The influence of tumor oxygenation on hypoxia imaging in murine squamous cell carcinoma using [64Cu]Cu-ATSM or [18F]Fluoromisonidazole positron emission tomography.
Journal: International journal of oncology 20070401
Title: Imaging tumoral hypoxia: oxygen concentrations and beyond.
Journal: Oncology (Williston Park, N.Y.) 20070301
Title: Motexafin gadolinium injection for the treatment of brain metastases in patients with non-small cell lung cancer.
Journal: International journal of nanomedicine 20070301
Title: Whole brain radiotherapy for brain metastases from breast cancer: estimation of survival using two stratification systems.
Journal: BMC cancer 20070101
Title: pO polarography, contrast enhanced color duplex sonography (CDS), [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography: validated methods for the evaluation of therapy-relevant tumor oxygenation or only bricks in the puzzle of tumor hypoxia?
Journal: BMC cancer 20070101
Title: Hypertabastic survival model.
Journal: Theoretical biology & medical modelling 20070101
Title: FDG--a marker of tumour hypoxia? A comparison with [18F]fluoromisonidazole and pO2-polarography in metastatic head and neck cancer.
Journal: European journal of nuclear medicine and molecular imaging 20061201
Title: Lack of correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in non-small cell lung cancer assessed by 18F-Fluoromisonidazole and 18F-FDG PET.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20061201
Title: A model to simulate tumour oxygenation and dynamic [18F]-Fmiso PET data.
Journal: Physics in medicine and biology 20061121
Title: Tumor hypoxia imaging.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060915
Title: Tumor hypoxia imaging with [F-18] fluoromisonidazole positron emission tomography in head and neck cancer.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060915
Title: Imaging hypoxia after oxygenation-modification: comparing [18F]FMISO autoradiography with pimonidazole immunohistochemistry in human xenograft tumors.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060801
Title: Combined uptake of [18F]FDG and [18F]FMISO correlates with radiation therapy outcome in head-and-neck cancer patients.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060801
Title: Characterization of fluoromisonidazole binding in stroke.
Journal: Stroke 20060701
Title: Ionizing radiation antagonizes tumor hypoxia induced by antiangiogenic treatment.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060601
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Prognostic significance of [18F]-misonidazole positron emission tomography-detected tumor hypoxia in patients with advanced head and neck cancer randomly assigned to chemoradiation with or without tirapazamine: a substudy of Trans-Tasman Radiation Oncology Group Study 98.02.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060501
Title: Interventions for preventing oral mucositis for patients with cancer receiving treatment.
Journal: The Cochrane database of systematic reviews 20060419
Title: NanoPET imaging of [(18)F]fluoromisonidazole uptake in experimental mouse tumours.
Journal: European journal of nuclear medicine and molecular imaging 20060301
Title: Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20060301
Title: Potentiation of the cytotoxicity of the anticancer agent tirapazamine by benzotriazine N-oxides: the role of redox equilibria.
Journal: Journal of the American Chemical Society 20060111
Title: A meta-analysis of hyperfractionated and accelerated radiotherapy and combined chemotherapy and radiotherapy regimens in unresected locally advanced squamous cell carcinoma of the head and neck.
Journal: BMC cancer 20060101
Title: Animal-specific positioning molds for registration of repeat imaging studies: comparative microPET imaging of F18-labeled fluoro-deoxyglucose and fluoro-misonidazole in rodent tumors.
Journal: Nuclear medicine and biology 20060101
Title: Establishment and characterization of multicellular spheroids from a human glioma cell line; Implications for tumor therapy.
Journal: Journal of translational medicine 20060101
Title: [18F] fluoromisonidazole and [18F] fluorodeoxyglucose positron emission tomography in response evaluation after chemo-/radiotherapy of non-small-cell lung cancer: a feasibility study.
Journal: BMC cancer 20060101
Title: Evaluation of hypoxic cell radio-sensitizers in terms of radio-sensitizing and repair-inhibiting potential. Dependency on p53 status of tumor cells and the effects on intratumor quiescent cells.
Journal: Anticancer research 20060101
Title: Radiosensitizers in cervical cancer. Cisplatin and beyond.
Journal: Radiation oncology (London, England) 20060101
Title: From anatomical to biological target volumes: the role of PET in radiation treatment planning.
Journal: Cancer imaging : the official publication of the International Cancer Imaging Society 20060101
Title: PET imaging of tumour hypoxia.
Journal: Cancer imaging : the official publication of the International Cancer Imaging Society 20060101
Title: CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo.
Journal: Journal of biology 20060101
Title: Fully automated synthesis of [18F]fluoromisonidazole using a conventional [18F]FDG module.
Journal: Nuclear medicine and biology 20051101
Title: Assessing regional hypoxia in human renal tumours using 18F-fluoromisonidazole positron emission tomography.
Journal: BJU international 20050901
Title: Effect of intratumoral heterogeneity in oxygenation status on FMISO PET, autoradiography, and electrode Po2 measurements in murine tumors.
Journal: International journal of radiation oncology, biology, physics 20050701
Title: Fully automated one-pot synthesis of [18F]fluoromisonidazole.
Journal: Nuclear medicine and biology 20050701
Title: A kinetic model for dynamic [18F]-Fmiso PET data to analyse tumour hypoxia.
Journal: Physics in medicine and biology 20050521
Title: Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models.
Journal: International journal of radiation oncology, biology, physics 20050401
Title: Gemcitabine twice weekly as a radiosensitiser for the treatment of brain metastases in patients with carcinoma: a phase I study.
Journal: British journal of cancer 20050314
Title: Oxaliplatin combined with infusional 5-fluorouracil and concomitant radiotherapy in inoperable and metastatic rectal cancer: a phase I trial.
Journal: British journal of cancer 20050227
Title: Prognostic impact of hypoxia imaging with 18F-misonidazole PET in non-small cell lung cancer and head and neck cancer before radiotherapy.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050201
Title: Hypoxia-specific tumor imaging with 18F-fluoroazomycin arabinoside.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050101
Title: Clinical practice guideline on the optimal radiotherapeutic management of brain metastases.
Journal: BMC cancer 20050101
Title: Imaging of the ischemic penumbra in acute stroke.
Journal: Korean journal of radiology 20050101
Title: Iodinated nitroimidazoles as radiosensitizers.
Journal: Anticancer research 20050101
Title: Measurement of tumor hypoxia in spontaneous canine sarcomas.
Journal: Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association 20050101
Title: Kinetic analysis of dynamic 18F-fluoromisonidazole PET correlates with radiation treatment outcome in head-and-neck cancer.
Journal: BMC cancer 20050101
Title: Evaluation of hypoxia in an experimental rat tumour model by [(18)F]fluoromisonidazole PET and immunohistochemistry.
Journal: British journal of cancer 20041129
Title: A preclinical model for noninvasive imaging of hypoxia-induced gene expression; comparison with an exogenous marker of tumor hypoxia.
Journal: European journal of nuclear medicine and molecular imaging 20041101
Title: The resistance to ischemia of white and gray matter after stroke.
Journal: Annals of neurology 20041101
Title: Assessment of hypoxia and perfusion in human brain tumors using PET with 18F-fluoromisonidazole and 15O-H2O.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20041101
Title: pO(2) Polarography versus positron emission tomography ([(18)F] fluoromisonidazole, [(18)F]-2-fluoro-2'-deoxyglucose). An appraisal of radiotherapeutically relevant hypoxia.
Journal: Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20041001
Title: Hypoxic tissue in ischaemic stroke: persistence and clinical consequences of spontaneous survival.
Journal: Brain : a journal of neurology 20040601
Title: In vivo evaluation of [18F]fluoroetanidazole as a new marker for imaging tumour hypoxia with positron emission tomography.
Journal: British journal of cancer 20040601
Title: Comparison of the biodistribution of two hypoxia markers [18F]FETNIM and [18F]FMISO in an experimental mammary carcinoma.
Journal: European journal of nuclear medicine and molecular imaging 20040401
Title: Imaging the ischemic penumbra with 18F-fluoromisonidazole in a rat model of ischemic stroke.
Journal: Stroke 20040401
Title: Penumbral topography in human stroke: methodology and validation of the 'Penumbragram'.
Journal: NeuroImage 20040401
Title: A phase III randomized study of misonidazole plus radiation vs. radiation alone for cervix cancer.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20040301
Title: Evidence that involucrin, a marker for differentiation, is oxygen regulated in human squamous cell carcinomas.
Journal: British journal of cancer 20040209
Title: Selective potentiation of the hypoxic cytotoxicity of tirapazamine by its 1-N-oxide metabolite SR 4317.
Journal: Cancer research 20040115
Title: Iodine-124-labeled iodo-azomycin-galactoside imaging of tumor hypoxia in mice with serial microPET scanning.
Journal: European journal of nuclear medicine and molecular imaging 20040101
Title: Topography and temporal evolution of hypoxic viable tissue identified by 18F-fluoromisonidazole positron emission tomography in humans after ischemic stroke.
Journal: Stroke 20031101
Title: GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON.
Journal: British journal of cancer 20031006
Title: Retinoblastoma protein expression is an independent predictor of both radiation response and survival in muscle-invasive bladder cancer.
Journal: British journal of cancer 20030721
Title: Nitroheterocyclic drugs with broad spectrum activity.
Journal: Parasitology research 20030601
Title: Tumour oxygenation assessed by 18F-fluoromisonidazole PET and polarographic needle electrodes in human soft tissue tumours.
Journal: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20030601
Title: Pimonidazole binding in C6 rat brain glioma: relation with lipid droplet detection.
Journal: British journal of cancer 20030506
Title: [(18)F]FMISO and [(18)F]FDG PET imaging in soft tissue sarcomas: correlation of hypoxia, metabolism and VEGF expression.
Journal: European journal of nuclear medicine and molecular imaging 20030501
Title: Accumulation of technetium-99m glucarate: in vitro cell cultures and in vivo tumour models.
Journal: Nuclear medicine communications 20030501
Title: [18F]Fluoroazomycinarabinofuranoside (18FAZA) and [18F]Fluoromisonidazole (18FMISO): a comparative study of their selective uptake in hypoxic cells and PET imaging in experimental rat tumors.
Journal: Nuclear medicine and biology 20030401
Title: Developments in radiotherapy and adjuvant chemotherapy for head and neck cancer.
Journal: Clinical otolaryngology and allied sciences 20030201
Title: A novel hypoxia-dependent 2-nitroimidazole KIN-841 inhibits tumour-specific angiogenesis by blocking production of angiogenic factors.
Journal: British journal of cancer 20030127
Title: On biologically conformal boost dose optimization.
Journal: Physics in medicine and biology 20030121
Title: A systematic overview of radiation therapy effects in urinary bladder cancer.
Journal: Acta oncologica (Stockholm, Sweden) 20030101
Title: 18F-Fluoroerythronitroimidazole radiation dosimetry in cancer studies.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20021201
Title: DNA-targeted 2-nitroimidazoles: studies of the influence of the phenanthridine-linked nitroimidazoles, 2-NLP-3 and 2-NLP-4, on DNA damage induced by ionizing radiation.
Journal: Radiation research 20020901
Title: The range of oxygenation in SiHa tumor xenografts.
Journal: Radiation research 20020801
Title: Oxygen-sensitive enzyme-prodrug gene therapy for the eradication of radiation-resistant solid tumours.
Journal: Gene therapy 20020701
Title: Statistical parametric mapping of hypoxic tissue identified by [(18)F]fluoromisonidazole and positron emission tomography following acute ischemic stroke.
Journal: NeuroImage 20020601
Title: Synthesis and evaluation of 4-bromo-1-(3-[18F]fluoropropyl)-2-nitroimidazole with a low energy LUMO orbital designed as brain hypoxia-targeting imaging agent.
Journal: Biological & pharmaceutical bulletin 20020501
Title: External-beam radiotherapy in the management of liver metastases.
Journal: Seminars in oncology 20020401
Title: Variation in mitochondrial function in hypoxia-sensitive and hypoxia-tolerant human glioma cells.
Journal: British journal of cancer 20020212
Title: Imaging and quantitation of the hypoxic cell fraction of viable tumor in an animal model of intracerebral high grade glioma using [18F]fluoromisonidazole (FMISO).
Journal: Nuclear medicine and biology 20020201
Title: Assessment of hypoxia in experimental mice tumours by [18F]fluoromisonidazole PET and pO2 electrode measurements. Influence of tumour volume and carbogen breathing.
Journal: Acta oncologica (Stockholm, Sweden) 20020101
Title: Hypoxia regulates avian cardiac Arnt and HIF-1alpha mRNA expression.
Journal: Biochemical and biophysical research communications 20010330
Title: Phase I trial of concurrent tirapazamine, cisplatin, and radiotherapy in patients with advanced head and neck cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010115
Title: Design, synthesis, and biological activity of anti-angiogenic hypoxic cell radiosensitizer haloacetylcarbamoyl-2-nitroimidazoles.
Journal: Bioorganic & medicinal chemistry 19970301
Title: Radioimmunotherapy for pancreatic carcinoma using (131)I-labeled monoclonal antibody Nd2 in xenografted nude mice.
Journal: Japanese journal of cancer research : Gann 19960901
Title: Neurotoxicity of misonidazole in rats following intravenous administration.
Journal: Pharmacological research 19960601
Title: The same chemicals induce different neurotoxicity when administered in high doses for short term or low doses for long term to rats and dogs.
Journal: Molecular and chemical neuropathology 19920101
Title: Non-invasive MRS in new anticancer drug development.
Journal: NMR in biomedicine 19920101
Title: Effects on tumour microcirculation in mice of misonidazole and tumour necrosis factor plus hyperthermia.
Journal: British journal of cancer 19920101
Title: The effect of radiosensitizers on radio-immunotherapy, using 131I-labelled anti-CEA antibodies in a human colonic xenograft model.
Journal: International journal of cancer 19910220
Title: Evaluation of a new 2-nitroimidazole nucleoside analogue, RK-28 as a radiosensitizer for clinical use.
Journal: International journal of radiation biology 19910101
Title: Toxicity of [PtCl2(NH3)L] in hypoxia; L = misonidazole or metronidazole.
Journal: Anti-cancer drug design 19900201
Title: The role of hemoglobin concentration in the outcome of misonidazole-sensitized radiotherapy of head and neck cancers: based on RTOG trial #79-15.
Journal: International journal of radiation oncology, biology, physics 19891201
Title: Hypoxic toxicity of misonidazole in a glucose-6-phosphate dehydrogenase deficient mutant Chinese hamster ovary cell line.
Journal: International journal of radiation oncology, biology, physics 19881001
Title: The radiosensitizing effects of misonidazole (MISO) in combination with diethyl maleate (DEM) in mouse mammary tumors.
Journal: International journal of radiation oncology, biology, physics 19861001
Title: Radiosensitizing effect of misonidazole in combination with an inhibitor of glutathione synthesis in murine tumors.
Journal: International journal of radiation oncology, biology, physics 19860901
Title: Effect of misonidazole on neurotransmitter systems.
Journal: International journal of radiation oncology, biology, physics 19860701
Title: Enhancement in the aerobic toxicity of misonidazole and SR-2508 by buthionine sulfoximine and 4-hydroxypyrazole: the role of hydrogen peroxide.
Journal: International journal of radiation oncology, biology, physics 19860701
Title: Misonidazole-induced chemopotentiation of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea toxicity in O6-methylguanine-DNA methyltransferase proficient (Mer+) and deficient (Mer-) cell lines.
Journal: Cancer research 19860601
Title: Biochemistry of misonidazole reduction by NADPH-cytochrome c (P-450) reductase.
Journal: Molecular pharmacology 19860201
Title: Altered pharmacokinetics in the mechanism of chemosensitization: effects of nitroimidazoles and other chemical modifiers on the pharmacokinetics, antitumour activity and acute toxicity of selected nitrogen mustards.
Journal: Cancer chemotherapy and pharmacology 19860101
Title: Effect of hypoxic cell radiosensitizers on glutathione level and related enzyme activities in isolated rat hepatocytes.
Journal: Life sciences 19850819
Title: Radiosensitizing and cytotoxic properties of misonidazole on glutathione synthetase deficient human fibroblasts.
Journal: International journal of radiation biology and related studies in physics, chemistry, and medicine 19850801
Title: Neurotoxicity of Adriamycin and misonidazole in the mouse.
Journal: Experimental neurology 19850101
Title: The neurotoxicity of radiosensitizing drugs: a biochemical assessment of desmethylmisonidazole (DMM) in the rat.
Journal: Toxicology 19850101
Title: Oncogenic transformation systems involving mammalian cells in vitro to determine the relative risks of different treatment modalities.
Journal: Strahlentherapie 19841201
Title: Drug testing using a soft agar stem cell assay on patient and xenograft tumor material.
Journal: International journal of radiation oncology, biology, physics 19840901
Title: Association of the radiosensitizers metronidazole and misonidazole (RO-07-0582) with bovine serum albumin. Effect of urea and ionic strength.
Journal: International journal of radiation biology and related studies in physics, chemistry, and medicine 19840801
Title: The effect of phenytoin, phenobarbitone, dexamethasone and flurbiprofen on misonidazole neurotoxicity in mice.
Journal: British journal of cancer 19840201
Title: The role of microsomal enzyme inducers in the reduction of misonidazole neurotoxicity.
Journal: The British journal of radiology 19831101
Title: Pharmacokinetic rationale for the interaction of 5-fluorouracil and misonidazole in humans.
Journal: British journal of cancer 19831101
Title: The labelling of EMT-6 tumours in BALB/C mice with 14C-misonidazole.
Journal: The British journal of radiology 19831001
Title: The role of dexamethasone in the modification of misonidazole pharmacokinetics.
Journal: British journal of cancer 19831001
Title: Protection against misonidazole-induced neuropathy in rats: a biochemical assessment.
Journal: Toxicology letters 19830601
Title: Modification of CCNU pharmacokinetics by misonidazole--a major mechanism of chemosensitization in mice.
Journal: British journal of cancer 19830501
Title: Effect of pretreatment with phenobarbital or SKF 525A on the toxicity and antitumor activity of lomustine.
Journal: Cancer treatment reports 19830301
Title: Nitroimidazoles as anaerobic electron acceptors for xanthine oxidase.
Journal: Biochemical pharmacology 19821015
Title: Structure/activity relationships for the enhancement by electron-affinic drugs of the anti-tumour effect of CCNU.
Journal: British journal of cancer 19820801
Title: Quantitative cytochemical assessment of the neurotoxicity of misonidazole in the mouse.
Journal: British journal of cancer 19820401
Title: Activation of misonidazole by rat liver microsomes and purified NADPH-cytochrome c reductase.
Journal: Biochemical pharmacology 19820215
Title: Reductive activation of nitroaromatics and enzyme inhibition: misonidazole and xanthine oxidase.
Journal: International journal of radiation oncology, biology, physics 19820101
Title: Enhancement by electron-affinic agents of the therapeutic effects of cytotoxic agents against the KHT tumor: structure-activity relationships.
Journal: International journal of radiation oncology, biology, physics 19820101
Title: Neurotoxicity of radiation sensitizers in the mouse.
Journal: International journal of radiation oncology, biology, physics 19820101
Title: A biochemical assessment of the neurotoxicity of the radiosensitizing drug misonidazole in the rat.
Journal: Clinical toxicology 19811201
Title: A biochemical method for assessing the neurotoxic effects of misonidazole in the rat.
Journal: British journal of cancer 19801201
Title: Structure-function dependence and allopurinol inhibition of radiosensitizer/nitroreductase interaction: approaches to improving therapeutic ratios.
Journal: Cancer clinical trials 19800101
Title: Binding of nitroreduction products of misonidazole to nucleic acids and protein.
Journal: Cancer clinical trials 19800101
Title: Effects of pretreatment with phenobarbitone and phenytoin on the pharmacokinetics and toxicity of phenytoin on the pharmacokinetics and toxicity of misonidazole in mice.
Journal: British journal of cancer 19790901
