Name: Name:tert-butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate
Brand: AABLOCKS
SKU: AA003PYE
Rating: 90 (10 reviews)

Catalog No.: AA003PYE

135716-08-4 | tert-butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate

Pack Size： 1g

Purity： 98%

in stock

$24.00 $17.00

Pack Size： 10g

Purity： 95%

in stock

$26.00 $18.00

Pack Size： 15g

Purity： 95%

in stock

$32.00 $23.00

Pack Size： 100g

Purity： 96%

in stock

$202.00 $142.00

Pack Size： 500g

Purity： 96%

in stock

$789.00 $553.00

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Technical Information

Catalog Number: AA003PYE

Chemical Name: tert-butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate

CAS Number: 135716-08-4

Molecular Formula: C14H23NO4

Molecular Weight: 269.3367

MDL Number: MFCD12912655

SMILES: CCOC(=O)C=C1CCN(CC1)C(=O)OC(C)(C)C

Properties

BP: 354°C at 760 mmHg

Form: Solid

MP: 85℃

Storage: Keep in dry area;2-8℃;

Complexity: 358

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 19

Hydrogen Bond Acceptor Count: 4

Hydrogen Bond Donor Count: 0

Isotope Atom Count: 0

Rotatable Bond Count: 5

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.7

Upstream Synthesis Route

135716-08-4

59184-90-6

[1]Patent:US2014/187581,2014,A1,

[2]Patent:WO2013/42135,2013,A1,

135716-08-4

89151-44-0

[1]Patent:CN102952072,2016,B,.Locationinpatent:Paragraph0110-0111

[2]BioorganicandMedicinalChemistryLetters,2003,vol.13,#13,p.2167-2172

[3]Patent:US2012/71461,2012,A1,

[4]Patent:CN107793408,2018,A,

[5]Patent:WO2018/68297,2018,A1,

[6]Patent:US6140333,2000,A,

135716-08-4

157688-46-5

[1]BioorganicandMedicinalChemistryLetters,2011,vol.21,#6,p.1880-1886

[2]ChineseChemicalLetters,2012,vol.23,#6,p.707-710

867-13-0

79099-07-3

135716-08-4

[1]Heterocycles,2001,vol.54,#2,p.747-755

[2]Patent:EP1498125,2005,A1,.Locationinpatent:Page/Pagecolumn84-85

[3]Patent:WO2018/152329,2018,A1,.Locationinpatent:Page/Pagecolumn48

[4]Patent:CN102952072,2016,B,.Locationinpatent:Paragraph0109

[5]ChineseChemicalLetters,2012,vol.23,#6,p.707-710

[6]Patent:CN107793408,2018,A,.Locationinpatent:Paragraph0168;0171

[7]Patent:WO2018/68297,2018,A1,.Locationinpatent:Page/Pagecolumn135

[8]JournalofOrganicChemistry,2016,vol.81,#3,p.1057-1074

[9]Patent:US2012/71461,2012,A1,.Locationinpatent:Page/Pagecolumn123;131

[10]RussianJournalofOrganicChemistry,2014,vol.50,#7,p.953-959

[11]Zh.Org.Khim.,2014,vol.50,#7,p.973-978,6

[12]Patent:CN105330698,2016,A,.Locationinpatent:Paragraph0220;0221;0222;0223

[13]Patent:WO2013/127269,2013,A1,.Locationinpatent:Page/Pagecolumn189

[14]BioorganicandMedicinalChemistryLetters,2003,vol.13,#13,p.2167-2172

[15]BioorganicandMedicinalChemistryLetters,2004,vol.14,#1,p.167-170

[16]Patent:WO2005/33108,2005,A1,.Locationinpatent:Page/Pagecolumn48

[17]Patent:US2003/191316,2003,A1,.Locationinpatent:Page/Pagecolumn32

[18]OrganicLetters,2011,vol.13,#7,p.1698-1701

[19]BioorganicandMedicinalChemistryLetters,2011,vol.21,#6,p.1880-1886

[20]Patent:EP2444402,2012,A1,.Locationinpatent:Page/Pagecolumn47

[21]ChemistryLetters,2012,vol.41,#12,p.1703-1705

[22]AngewandteChemie-InternationalEdition,2013,vol.52,#33,p.8597-8601

[23]Angew.Chem.,2013,vol.125,#33,p.8759-8763,5

[24]Patent:WO2014/15495,2014,A1,.Locationinpatent:Page/Pagecolumn37;38

[25]Patent:WO2014/18764,2014,A1,.Locationinpatent:Page/Pagecolumn40

[26]RussianJournalofOrganicChemistry,2014,vol.50,#1,p.54-58

[27]Zh.Org.Khim.,2014,vol.50,#1,p.61-65,5

[28]BioorganicandMedicinalChemistryLetters,2014,vol.24,#23,p.5502-5506

[29]Patent:WO2015/17305,2015,A1,.Locationinpatent:Page/Pagecolumn61;62

[30]Patent:WO2016/65582,2016,A1,.Locationinpatent:Page/Pagecolumn44-45

[31]Patent:WO2016/122994,2016,A1,.Locationinpatent:Page/Pagecolumn43

[32]Patent:WO2016/60941,2016,A1,.Locationinpatent:Page/Pagecolumn51

[33]AngewandteChemie-InternationalEdition,2017,vol.56,#33,p.9868-9871

[34]Angew.Chem.,2017,vol.129,p.10000-10003,4

[35]Patent:CN107540659,2018,A,.Locationinpatent:Paragraph0190

79099-07-3

1099-45-2

135716-08-4

[1]Patent:WO2015/949,2015,A1,.Locationinpatent:Page/Pagecolumn117

[2]Patent:US2014/187581,2014,A1,.Locationinpatent:Paragraph0155-0157

[3]EuropeanJournalofMedicinalChemistry,1999,vol.34,#5,p.363-380

Downstream Synthesis Route

135716-08-4

135716-09-5

[1]Heterocycles,2001,vol.54,p.747-755

[2]Patent:WO2018/68297,2018,A1.Locationinpatent:Page/Pagecolumn135;136

[3]Patent:WO2018/152329,2018,A1.Locationinpatent:Page/Pagecolumn48

[4]JournaloftheChemicalSociety.PerkintransactionsI,1995,p.641-644

[5]ChineseChemicalLetters,2012,vol.23,p.707-710

[6]Patent:WO2013/42135,2013,A1.Locationinpatent:Page/Pagecolumn18;19

[7]Patent:US2014/187581,2014,A1.Locationinpatent:Paragraph0158-0161

[8]Patent:US2012/71461,2012,A1.Locationinpatent:Page/Pagecolumn123-124;131-132

[9]BioorganicandMedicinalChemistryLetters,2003,vol.13,p.2167-2172

[10]Patent:US5073557,1991,A

[11]Patent:US2003/191316,2003,A1.Locationinpatent:Page/Pagecolumn32

[12]Patent:US2003/229074,2003,A1.Locationinpatent:Page20

[13]BioorganicandMedicinalChemistryLetters,2011,vol.21,p.1880-1886

[14]AngewandteChemie-InternationalEdition,2013,vol.52,p.8597-8601 Angew.Chem.,2013,vol.125,p.8759-8763,5

[15]Patent:WO2015/112441,2015,A1.Locationinpatent:Page/Pagecolumn62

[16]Patent:US2016/333021,2016,A1.Locationinpatent:Paragraph0370

[17]Patent:CN107793408,2018,A.Locationinpatent:Paragraph0168;0172

[18]Patent:US6140333,2000,A

[19]Patent:US5753664,1998,A

867-13-0

79099-07-3

135716-08-4

[1]Heterocycles,2001,vol.54,p.747-755

[2]Patent:EP1498125,2005,A1.Locationinpatent:Page/Pagecolumn84-85

[3]Patent:WO2018/152329,2018,A1.Locationinpatent:Page/Pagecolumn48

[4]Patent:CN102952072,2016,B.Locationinpatent:Paragraph0109

[5]ChineseChemicalLetters,2012,vol.23,p.707-710

[6]Patent:CN107793408,2018,A.Locationinpatent:Paragraph0168;0171

[7]Patent:WO2018/68297,2018,A1.Locationinpatent:Page/Pagecolumn135

[8]JournalofOrganicChemistry,2016,vol.81,p.1057-1074

[9]Patent:US2012/71461,2012,A1.Locationinpatent:Page/Pagecolumn123;131

[10]RussianJournalofOrganicChemistry,2014,vol.50,p.953-959 Zh.Org.Khim.,2014,vol.50,p.973-978,6

[11]Patent:US2019/382384,2019,A1.Locationinpatent:Paragraph0473;0474

[12]Patent:WO2019/239371,2019,A1.Locationinpatent:Page/Pagecolumn56;57

[13]Patent:CN105330698,2016,A.Locationinpatent:Paragraph0220;0221;0222;0223

[14]Patent:WO2013/127269,2013,A1.Locationinpatent:Page/Pagecolumn189

[15]BioorganicandMedicinalChemistryLetters,2003,vol.13,p.2167-2172

[16]BioorganicandMedicinalChemistryLetters,2004,vol.14,p.167-170

[17]Patent:WO2005/33108,2005,A1.Locationinpatent:Page/Pagecolumn48

[18]Patent:US2003/191316,2003,A1.Locationinpatent:Page/Pagecolumn32

[19]OrganicLetters,2011,vol.13,p.1698-1701

[20]BioorganicandMedicinalChemistryLetters,2011,vol.21,p.1880-1886

[21]Patent:EP2444402,2012,A1.Locationinpatent:Page/Pagecolumn47

[22]ChemistryLetters,2012,vol.41,p.1703-1705

[23]AngewandteChemie-InternationalEdition,2013,vol.52,p.8597-8601 Angew.Chem.,2013,vol.125,p.8759-8763,5

[24]Patent:WO2014/15495,2014,A1.Locationinpatent:Page/Pagecolumn37;38

[25]Patent:WO2014/18764,2014,A1.Locationinpatent:Page/Pagecolumn40

[26]RussianJournalofOrganicChemistry,2014,vol.50,p.54-58 Zh.Org.Khim.,2014,vol.50,p.61-65,5

[27]BioorganicandMedicinalChemistryLetters,2014,vol.24,p.5502-5506

[28]Patent:WO2015/17305,2015,A1.Locationinpatent:Page/Pagecolumn61;62

[29]Patent:WO2016/65582,2016,A1.Locationinpatent:Page/Pagecolumn44-45

[30]Patent:WO2016/122994,2016,A1.Locationinpatent:Page/Pagecolumn43

[31]Patent:WO2016/60941,2016,A1.Locationinpatent:Page/Pagecolumn51

[32]AngewandteChemie-InternationalEdition,2017,vol.56,p.9868-9871 Angew.Chem.,2017,vol.129,p.10000-10003,4

[33]Patent:CN107540659,2018,A.Locationinpatent:Paragraph0190

[34]Patent:EP3567030,2019,A1.Locationinpatent:Paragraph0173-0174

[35]Patent:WO2020/48830,2020,A1.Locationinpatent:Page/Pagecolumn235

[36]Patent:WO2020/48831,2020,A1.Locationinpatent:Page/Pagecolumn225

135716-08-4

193085-24-4

[1]ChineseChemicalLetters,2012,vol.23,p.707-710

[2]EuropeanJournalofMedicinalChemistry,1999,vol.34,p.363-380

[3]Patent:EP1489078,2004,A1.Locationinpatent:Page189

79099-07-3

1099-45-2

135716-08-4

[1]Patent:WO2015/949,2015,A1.Locationinpatent:Page/Pagecolumn117

[2]Patent:US2014/187581,2014,A1.Locationinpatent:Paragraph0155-0157

[3]EuropeanJournalofOrganicChemistry,2019,vol.2019,p.5219-5229

[4]EuropeanJournalofMedicinalChemistry,1999,vol.34,p.363-380

[5]Patent:WO2019/63748,2019,A1.Locationinpatent:Page/Pagecolumn248-249

135716-08-4

89151-44-0

[1]Patent:CN102952072,2016,B.Locationinpatent:Paragraph0110-0111

[2]BioorganicandMedicinalChemistryLetters,2003,vol.13,p.2167-2172

[3]Patent:US2012/71461,2012,A1

[4]Patent:CN107793408,2018,A

[5]Patent:WO2018/68297,2018,A1

[6]Patent:US6140333,2000,A

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